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Protein

Solute carrier family 35 member G2

Gene

Slc35g2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 35 member G2
Alternative name(s):
Transmembrane protein 22
Gene namesi
Name:Slc35g2
Synonyms:Tmem22
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2685365 Slc35g2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei105 – 125HelicalSequence analysisAdd BLAST21
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21
Transmembranei169 – 189HelicalSequence analysisAdd BLAST21
Transmembranei194 – 214HelicalSequence analysisAdd BLAST21
Transmembranei218 – 238HelicalSequence analysisAdd BLAST21
Transmembranei255 – 275HelicalSequence analysisAdd BLAST21
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Transmembranei319 – 339HelicalSequence analysisAdd BLAST21
Transmembranei346 – 366HelicalSequence analysisAdd BLAST21
Transmembranei368 – 388HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004161191 – 412Solute carrier family 35 member G2Add BLAST412

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei409PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiD3YVE8
PaxDbiD3YVE8
PRIDEiD3YVE8

PTM databases

iPTMnetiD3YVE8
PhosphoSitePlusiD3YVE8

Expressioni

Gene expression databases

BgeeiENSMUSG00000070287 Expressed in 38 organ(s), highest expression level in cerebellum

Structurei

3D structure databases

ProteinModelPortaliD3YVE8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini121 – 237EamA 1Add BLAST117
Domaini268 – 388EamA 2Add BLAST121

Sequence similaritiesi

Belongs to the SLC35G solute transporter family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IJVP Eukaryota
ENOG410YGWG LUCA
GeneTreeiENSGT00730000110996
HOGENOMiHOG000059600
InParanoidiD3YVE8
OMAiIFPSVYD
OrthoDBiEOG091G070D
PhylomeDBiD3YVE8
TreeFamiTF331838

Family and domain databases

InterProiView protein in InterPro
IPR000620 EamA_dom
PfamiView protein in Pfam
PF00892 EamA, 2 hits

Sequencei

Sequence statusi: Complete.

D3YVE8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDTSPSKKYP IKKRVKIHPN TVMVKYTSHY PQPGDDGYEE INEDYGRFME
60 70 80 90 100
ENPKKSLLSE MRRKGRTLFG TMDTQPSSSE DPRASGMGQF QSFAEKNIFQ
110 120 130 140 150
SRKMWLVLFG SALAHGCVAL ITRLISDRSK VPSLELIFIR SVLQVLSVIV
160 170 180 190 200
VCYYQEAPFG PSGYRLRLFF YGVCNVISIT CAYTSFSIVP PSNGTTMWRA
210 220 230 240 250
TTTVFSAILA FLLVDEKMAY VDMATVVCSI LGVCLVMIPN IADEDNSLLN
260 270 280 290 300
AWKEAFGYTM TVMAGLTTAL SMIVYRSIRE KISMWTALFT FGWTGTIWGL
310 320 330 340 350
STMFVLQEPI IPLDGATWSY LIAICLCSTA AFLGVYYALD KFHPALVSTV
360 370 380 390 400
QHLEIVVAMV LQLLVLHIFP SVYDVFGGVI IMISVFVLAG YKLYWRNVRR
410
EDYQEILDSP IK
Length:412
Mass (Da):46,395
Last modified:April 20, 2010 - v1
Checksum:i975066E4E68A7E4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129223 Genomic DNA No translation available.
CH466560 Genomic DNA Translation: EDL21032.1
CCDSiCCDS52898.1
RefSeqiNP_001094953.1, NM_001101483.1
UniGeneiMm.236289

Genome annotation databases

EnsembliENSMUST00000093792; ENSMUSP00000091308; ENSMUSG00000070287
GeneIDi245020
KEGGimmu:245020
UCSCiuc012gze.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129223 Genomic DNA No translation available.
CH466560 Genomic DNA Translation: EDL21032.1
CCDSiCCDS52898.1
RefSeqiNP_001094953.1, NM_001101483.1
UniGeneiMm.236289

3D structure databases

ProteinModelPortaliD3YVE8
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiD3YVE8
PhosphoSitePlusiD3YVE8

Proteomic databases

MaxQBiD3YVE8
PaxDbiD3YVE8
PRIDEiD3YVE8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000093792; ENSMUSP00000091308; ENSMUSG00000070287
GeneIDi245020
KEGGimmu:245020
UCSCiuc012gze.1 mouse

Organism-specific databases

CTDi80723
MGIiMGI:2685365 Slc35g2

Phylogenomic databases

eggNOGiENOG410IJVP Eukaryota
ENOG410YGWG LUCA
GeneTreeiENSGT00730000110996
HOGENOMiHOG000059600
InParanoidiD3YVE8
OMAiIFPSVYD
OrthoDBiEOG091G070D
PhylomeDBiD3YVE8
TreeFamiTF331838

Miscellaneous databases

PROiPR:D3YVE8
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000070287 Expressed in 38 organ(s), highest expression level in cerebellum

Family and domain databases

InterProiView protein in InterPro
IPR000620 EamA_dom
PfamiView protein in Pfam
PF00892 EamA, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiS35G2_MOUSE
AccessioniPrimary (citable) accession number: D3YVE8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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