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Protein
Submitted name:

Mixed lineage kinase domain-like protein

Gene

Mlkl

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Mixed lineage kinase domain-like proteinImported
Gene namesi
Name:MlklImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1921818 Mlkl

PTM / Processingi

Proteomic databases

MaxQBiD3YV42
PeptideAtlasiD3YV42
PRIDEiD3YV42

Expressioni

Gene expression databases

BgeeiENSMUSG00000012519 Expressed in 95 organ(s), highest expression level in intestine
ExpressionAtlasiD3YV42 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiD3YV42
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili69 – 89Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0192 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00390000016453
HOGENOMiHOG000171496

Family and domain databases

Gene3Di1.20.930.20, 1 hit
InterProiView protein in InterPro
IPR036537 Adaptor_Cbl_N_dom_sf

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

D3YV42-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAFEERQKMD KLGQIIKLGQ LIYEQCEKMK YCRKQCQRLG NRVHGLLQPL
60 70 80 90 100
QRLQAQGKKN LPDDITAALG RFDEVLKEAN QQIEKFSKKS HIWKFVSVGN
110 120 130 140 150
DKILFHEVNE KLRDVWEELL LLLQVYHWNT VSDVSQPASW QQEDRQDAEE
160 170
DGNENMKVIL MQLQISVEEI NKTLKQ
Length:176
Mass (Da):20,751
Last modified:April 20, 2010 - v1
Checksum:i95A717585F1DCBED
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9D2Y4MLKL_MOUSE
Mixed lineage kinase domain-like pr...
Mlkl
472Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei176Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC163625 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000145862; ENSMUSP00000114701; ENSMUSG00000012519

Similar proteinsi

Entry informationi

Entry nameiD3YV42_MOUSE
AccessioniPrimary (citable) accession number: D3YV42
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 12, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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