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Protein
Submitted name:

Cingulin

Gene

Cgn

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-MMU-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)

Names & Taxonomyi

Protein namesi
Submitted name:
CingulinImported
Gene namesi
Name:CgnImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1927237 Cgn

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiD3YUW7
PeptideAtlasiD3YUW7
PRIDEiD3YUW7

Expressioni

Gene expression databases

BgeeiENSMUSG00000068876 Expressed in 183 organ(s), highest expression level in blastocyst
ExpressionAtlasiD3YUW7 baseline and differential

Structurei

3D structure databases

SMRiD3YUW7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini799 – 1134Myosin_tail_1InterPro annotationAdd BLAST336

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili342 – 362Sequence analysisAdd BLAST21
Coiled coili370 – 397Sequence analysisAdd BLAST28
Coiled coili447 – 484Sequence analysisAdd BLAST38
Coiled coili500 – 548Sequence analysisAdd BLAST49
Coiled coili556 – 601Sequence analysisAdd BLAST46
Coiled coili608 – 635Sequence analysisAdd BLAST28
Coiled coili640 – 691Sequence analysisAdd BLAST52
Coiled coili699 – 733Sequence analysisAdd BLAST35
Coiled coili741 – 881Sequence analysisAdd BLAST141
Coiled coili889 – 1014Sequence analysisAdd BLAST126
Coiled coili1028 – 1143Sequence analysisAdd BLAST116

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IGSJ Eukaryota
ENOG410YEC7 LUCA
GeneTreeiENSGT00730000110843
HOGENOMiHOG000168265
OMAiTMAEPRG

Family and domain databases

InterProiView protein in InterPro
IPR002928 Myosin_tail
PfamiView protein in Pfam
PF01576 Myosin_tail_1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

D3YUW7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMADPRGPVD HGVQIRFITE PEGATEMGTL RRSGRRPARD ARASTYGVAV
60 70 80 90 100
RVQGIAGQPF VVLNSGEKGT DSFGVQIKGG NNRGSPGALS SDSELPENPY
110 120 130 140 150
SQVKGRPATS RSSTSDEEPK DHLNGKLIRS QSQASLTGLA FMSPSNRSTS
160 170 180 190 200
LLELAPKPTS SINTIDTAPL SSVDSLINKF DSQKGGQVRG RTGRRTRTLP
210 220 230 240 250
HEQRKRSQSL DSRLPRDTRE EREHQSANHW TRGTKYDNHV DSSKNPSQKQ
260 270 280 290 300
SPFSSFSRSR QTQDWVLQSF EETRDPAMVQ FKSTPDLLRD QRETAPPGSA
310 320 330 340 350
DHVKATIYGI LREGSSESEA SVRRKVSLVL EQMQPLGALA GQAELTRKME
360 370 380 390 400
ELQKKLDEEV KKRQKLEPSR VGLERQLEEK AEECHRLQEL LERRKGEVQQ
410 420 430 440 450
SSKELQNMKL LLGQEEGLRH GLEAQVKELQ LKLKHSQSPD SGKESLLKDL
460 470 480 490 500
LDTRELLEEL LEGKQRVEEQ LRLRERELTA LKGALKEEVA SHDQEVEHVR
510 520 530 540 550
LQYQRDTEQL RRSMQDATQD HAALEAERQK MSSLVRELQR ELEETSEETG
560 570 580 590 600
HWQSMFQKNK EELRATKQEL LQLRMEKEEM EEELGEKMEV LQRDLEQARA
610 620 630 640 650
STRDTHQVEE LKKELRRTQG ELKELQAEQQ NQEVTGRHQN QVLEKQLAAL
660 670 680 690 700
REEADRGREL EQQNLQLQKT LQQLRQDCEE ASKAKVASET EAMVLGQRRA
710 720 730 740 750
TVETTLRETQ EENDEFRRRI LGLEQQLKEA RGLAEGGEAV EARLRDKVHR
760 770 780 790 800
LEVEKQQLEE ALNAAREEEG NLAAAKRALE VRLDEAQRGL ARLGQEQQAL
810 820 830 840 850
NRALEEEGKQ REALRRSKAE LEEQKRLLNR TVDRLNKELE QIGDDSKLAL
860 870 880 890 900
QQLQAQMEDY KEKARKEVAD AQRQAKDWAS EAEKNSGGLS RLQDELQRLR
910 920 930 940 950
QALQTSQAER DTARLDKELL AQRLQGLEQE AENKKRFQDD KARQLKSLEE
960 970 980 990 1000
KVSRLEAELD EEKNTVELLT DRVNRGRDQV DQLRTELMQE RSARQDLECD
1010 1020 1030 1040 1050
KISLERQNKD LKTRLASSEG FQKPSASLSQ LESQNQLLQE RLQAEEREKT
1060 1070 1080 1090 1100
VLQSTNRKLE RRVKELSIQI DDERQHVNDQ KDQLTLRVKA LKRQVDEAEE
1110 1120 1130 1140 1150
EIERLDSLRK KAQRELEEQH EVNEQLQARI KSLEKDAWRK ASRSAAESAL
1160 1170 1180
KQEGLSSDEE FDNVYDPSSI ASLLTESNLQ TSSC
Length:1,184
Mass (Da):135,744
Last modified:April 20, 2010 - v1
Checksum:i0CB348020FAA6642
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P59242CING_MOUSE
Cingulin
Cgn Kiaa1319
1,191Annotation score:
E9QMC1E9QMC1_MOUSE
Cingulin
Cgn
1,192Annotation score:
A0A0G2JFG0A0A0G2JFG0_MOUSE
Cingulin
Cgn mCG_13712
404Annotation score:
A0A0G2JEK8A0A0G2JEK8_MOUSE
Cingulin
Cgn
449Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC150033 Genomic DNA No translation available.
AC158989 Genomic DNA No translation available.
RefSeqiNP_001280656.1, NM_001293727.1
UniGeneiMm.87634

Genome annotation databases

EnsembliENSMUST00000107272; ENSMUSP00000102893; ENSMUSG00000068876
GeneIDi70737
UCSCiuc008qgz.3 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC150033 Genomic DNA No translation available.
AC158989 Genomic DNA No translation available.
RefSeqiNP_001280656.1, NM_001293727.1
UniGeneiMm.87634

3D structure databases

SMRiD3YUW7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiD3YUW7
PeptideAtlasiD3YUW7
PRIDEiD3YUW7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000107272; ENSMUSP00000102893; ENSMUSG00000068876
GeneIDi70737
UCSCiuc008qgz.3 mouse

Organism-specific databases

CTDi57530
MGIiMGI:1927237 Cgn

Phylogenomic databases

eggNOGiENOG410IGSJ Eukaryota
ENOG410YEC7 LUCA
GeneTreeiENSGT00730000110843
HOGENOMiHOG000168265
OMAiTMAEPRG

Enzyme and pathway databases

ReactomeiR-MMU-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000068876 Expressed in 183 organ(s), highest expression level in blastocyst
ExpressionAtlasiD3YUW7 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002928 Myosin_tail
PfamiView protein in Pfam
PF01576 Myosin_tail_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3YUW7_MOUSE
AccessioniPrimary (citable) accession number: D3YUW7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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