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Protein
Submitted name:

Myosin-binding protein C, slow-type

Gene

Mybpc1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • actin filament binding Source: GO_Central
  • muscle alpha-actinin binding Source: GO_Central
  • structural constituent of cytoskeleton Source: MGI
  • structural constituent of muscle Source: GO_Central

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-390522 Striated Muscle Contraction

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin-binding protein C, slow-typeImported
Submitted name:
RIKEN cDNA 8030451F13, isoform CRA_cImported
Gene namesi
Name:Mybpc1Imported
Synonyms:8030451F13RikImported
ORF Names:mCG_16786Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1336213 Mybpc1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000020061 Expressed in 163 organ(s), highest expression level in diaphragm

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112699

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini327 – 414Ig-likeInterPro annotationAdd BLAST88
Domaini509 – 602Ig-likeInterPro annotationAdd BLAST94
Domaini609 – 708Fibronectin type-IIIInterPro annotationAdd BLAST100
Domaini709 – 802Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini806 – 894Ig-likeInterPro annotationAdd BLAST89
Domaini903 – 998Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini1016 – 1104Ig-likeInterPro annotationAdd BLAST89

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IFCI Eukaryota
ENOG4110AYI LUCA
GeneTreeiENSGT00860000133685
HOGENOMiHOG000220906
KOiK12557
OrthoDBiEOG091G00ND

Family and domain databases

CDDicd00063 FN3, 3 hits
Gene3Di2.60.40.10, 11 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF00041 fn3, 3 hits
PF07679 I-set, 7 hits
SMARTiView protein in SMART
SM00060 FN3, 3 hits
SM00409 IG, 7 hits
SM00408 IGc2, 3 hits
SUPFAMiSSF48726 SSF48726, 7 hits
SSF49265 SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 3 hits
PS50835 IG_LIKE, 4 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

D3YU50-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPEPTKKEEN EVSAPAPPPE EWSLGESPAG GEEQDKQNAN SQLSTLFVEK
60 70 80 90 100
PQTGSVKVGA NITFVAKVRA EDLLRKPTVK WFKGKWMDLA SKAGKHLQLK
110 120 130 140 150
ETFERQTRVY TFEMQIIKAK ENYAGNYRCE VTYKDKFDSC SFDLEVHEST
160 170 180 190 200
GTTPNIDIRS AFKRSGEGQE DAGELDFSGL LKRREVKQQE EEPEIDVWEL
210 220 230 240 250
LKNANPNEYE KIAFQYGITD LRGMLKRLKR MRRVEKKSAA FAKILDPAYQ
260 270 280 290 300
VDKGGKVRFV VELADPKLEV KWFKNGQEIR PSTKYIFEHK GNERIMFINN
310 320 330 340 350
CSLTDDSEYY VTAGDEKCST ELFVREPPIM VTKQLEDMNA YCGERVEMEV
360 370 380 390 400
EVSEDDANVK WFKNGEEIFP GPKSRYKIKV EGKKHTLIIE GATKADSAEY
410 420 430 440 450
SAMTTGGQSS AKLSVDLRPL KITTPLTDQT VKLGKEVCLK CEISENVPGK
460 470 480 490 500
WTKNGLPVQE GERLKVVHKG RIHKLVIANA LIEDEGEYVF TPDAYNVPLS
510 520 530 540 550
AKVHVIDPPK IILDGLDADN TVTVIAGSKL RLEIPVTGEP PPKAIWSRAD
560 570 580 590 600
KAIMEGSGRI RAESYPDSST LVIDVAERDD SGVYNINLKN EAGEAHASIK
610 620 630 640 650
IKVVDIPDPP VAPNVTEVGD DWCIMNWEPP AYDGGSPILG YFIERKKKQS
660 670 680 690 700
SRWMRLNFDL CKETTFEPKK MIEGVAYEVR IFAVNAIGIS KPSMPSKPFV
710 720 730 740 750
PLAVTSPPTL LAVDSVTDSS VTMKWRPPDQ IGAAGLDGYV LEYCFEGTED
760 770 780 790 800
WIVANTDLID KTKFTINGLP TDAKIFVRVK AINAAGASEP KYYSQPILVK
810 820 830 840 850
EIIEPPKIRI PRHLKQTYIR RVGEAVNLVI PFQGKPRPEL TWKKDGEEID
860 870 880 890 900
KNQINIRNSE TDTIIFIRKA ERSHSGKYDL QVKVDKYVEN ASIDIQIVDR
910 920 930 940 950
PGPPQTVTIE DVWGENVALT WTPPKDDGNA AITGYTIQKA DKKSMEWFTV
960 970 980 990 1000
IEHYHRTNAT ITELVIGNEY YFRVFAENMC GLSEDATMTK ESAVIAKDGK
1010 1020 1030 1040 1050
IYKNPVYEDF NFTEAPMFTQ PLVNTYAIAG YNATLNCSVR GNPKPKITWM
1060 1070 1080 1090 1100
KNKVAIVDDP RYRMFSNQGV CTLEIRKPSP YDGGTYCCKA VNDLGTVEIE
1110 1120
CKLEVKVIYQ GVNTPGQPVS LEGQQQS
Length:1,127
Mass (Da):126,559
Last modified:April 20, 2010 - v1
Checksum:iD7CBB1F09D59E441
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6P6L5Q6P6L5_MOUSE
Myosin-binding protein C, slow-type
Mybpc1 8030451F13Rik, mCG_16786
1,124Annotation score:
F6RQD1F6RQD1_MOUSE
Myosin-binding protein C, slow-type
Mybpc1
626Annotation score:
F7D574F7D574_MOUSE
Myosin-binding protein C, slow-type
Mybpc1
362Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164567 Genomic DNA No translation available.
AC165357 Genomic DNA No translation available.
CH466539 Genomic DNA Translation: EDL21488.1
RefSeqiNP_001239301.1, NM_001252372.1
UniGeneiMm.147208

Genome annotation databases

EnsembliENSMUST00000119185; ENSMUSP00000112699; ENSMUSG00000020061
GeneIDi109272
KEGGimmu:109272
UCSCiuc007gru.3 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164567 Genomic DNA No translation available.
AC165357 Genomic DNA No translation available.
CH466539 Genomic DNA Translation: EDL21488.1
RefSeqiNP_001239301.1, NM_001252372.1
UniGeneiMm.147208

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112699

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000119185; ENSMUSP00000112699; ENSMUSG00000020061
GeneIDi109272
KEGGimmu:109272
UCSCiuc007gru.3 mouse

Organism-specific databases

CTDi4604
MGIiMGI:1336213 Mybpc1

Phylogenomic databases

eggNOGiENOG410IFCI Eukaryota
ENOG4110AYI LUCA
GeneTreeiENSGT00860000133685
HOGENOMiHOG000220906
KOiK12557
OrthoDBiEOG091G00ND

Enzyme and pathway databases

ReactomeiR-MMU-390522 Striated Muscle Contraction

Miscellaneous databases

ChiTaRSiMybpc1 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020061 Expressed in 163 organ(s), highest expression level in diaphragm

Family and domain databases

CDDicd00063 FN3, 3 hits
Gene3Di2.60.40.10, 11 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF00041 fn3, 3 hits
PF07679 I-set, 7 hits
SMARTiView protein in SMART
SM00060 FN3, 3 hits
SM00409 IG, 7 hits
SM00408 IGc2, 3 hits
SUPFAMiSSF48726 SSF48726, 7 hits
SSF49265 SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 3 hits
PS50835 IG_LIKE, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiD3YU50_MOUSE
AccessioniPrimary (citable) accession number: D3YU50
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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