UniProtKB - D3YTX5 (D3YTX5_MOUSE)
Protein
Taste receptor type 2
Gene
Vmn1r259
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- pheromone receptor activity Source: InterPro
GO - Biological processi
- response to pheromone Source: UniProtKB-KW
- sensory perception of taste Source: UniProtKB-KW
Keywordsi
Molecular function | G-protein coupled receptorUniRule annotationARBA annotation, Receptor, Transducer |
Biological process | Pheromone responseARBA annotation, Sensory transduction, TasteUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Taste receptor type 2UniRule annotation |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:3782353, Vmn1r248 MGI:3782392, Vmn1r259 |
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- Membrane UniRule annotationARBA annotation; Multi-pass membrane protein UniRule annotationARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 14 – 36 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 57 – 78 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 98 – 121 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 196 – 212 | HelicalSequence analysisAdd BLAST | 17 | |
Transmembranei | 239 – 263 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 269 – 292 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 27 – 290 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 264 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | ENOG502R0MZ, Eukaryota |
GeneTreei | ENSGT00960000186612 |
HOGENOMi | CLU_058641_1_0_1 |
OrthoDBi | 934923at2759 |
Family and domain databases
CDDi | cd13949, 7tm_V1R_pheromone, 1 hit |
InterProi | View protein in InterPro IPR017452, GPCR_Rhodpsn_7TM IPR007960, TAS2R IPR004072, Vmron_rcpt_1 |
PANTHERi | PTHR24062, PTHR24062, 1 hit |
Pfami | View protein in Pfam PF05296, TAS2R, 1 hit |
PROSITEi | View protein in PROSITE PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
i Sequence
Sequence statusi: Complete.
D3YTX5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDHGKSVKT TEEVALQLLL LCQFGVGTLA NVFLFVHNFS PVLTGSKQRP
60 70 80 90 100
RQVILSHMAM ANALTLFLTI FPNNMIAFAP KTPPTELKCK LEFFSHMVAR
110 120 130 140 150
STNLCSTCVL SIHQFVTLVL VNRGKLILRA SVPNFVSYSC YSCWFFSVLS
160 170 180 190 200
NIHIPIKVTG PQITDNNTDS KSNLFCSTSG FIVGIVFLQF AYDATFMSIM
210 220 230 240 250
VWTSVSMILL LHRHRQRMQH ILTPNQNPRG QAETRATRTI LMLVVTFVSF
260 270 280 290 300
YLLNFICIIF HTLLMHSHLF IRLVSEVLAA VFPSICPLLL IFRDPKDPCS
VLFNC
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC122819 Genomic DNA No translation available. AC147564 Genomic DNA No translation available. |
RefSeqi | NP_001160638.1, NM_001167166.1 NP_001160639.1, NM_001167167.1 |
Genome annotation databases
Ensembli | ENSMUST00000105196; ENSMUSP00000100831; ENSMUSG00000096760 ENSMUST00000168926; ENSMUSP00000131872; ENSMUSG00000094532 |
GeneIDi | 100043025 100043083 |
KEGGi | mmu:100043025 mmu:100043083 |
UCSCi | uc012fdj.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC122819 Genomic DNA No translation available. AC147564 Genomic DNA No translation available. |
RefSeqi | NP_001160638.1, NM_001167166.1 NP_001160639.1, NM_001167167.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
GPCRDBi | Search... |
Genome annotation databases
Ensembli | ENSMUST00000105196; ENSMUSP00000100831; ENSMUSG00000096760 ENSMUST00000168926; ENSMUSP00000131872; ENSMUSG00000094532 |
GeneIDi | 100043025 100043083 |
KEGGi | mmu:100043025 mmu:100043083 |
UCSCi | uc012fdj.1, mouse |
Organism-specific databases
CTDi | 100043025 100043083 |
MGIi | MGI:3782353, Vmn1r248 MGI:3782392, Vmn1r259 |
Phylogenomic databases
eggNOGi | ENOG502R0MZ, Eukaryota |
GeneTreei | ENSGT00960000186612 |
HOGENOMi | CLU_058641_1_0_1 |
OrthoDBi | 934923at2759 |
Miscellaneous databases
BioGRID-ORCSi | 100043025, 0 hits in 7 CRISPR screens 100043083, 2 hits in 5 CRISPR screens |
SOURCEi | Search... |
Family and domain databases
CDDi | cd13949, 7tm_V1R_pheromone, 1 hit |
InterProi | View protein in InterPro IPR017452, GPCR_Rhodpsn_7TM IPR007960, TAS2R IPR004072, Vmron_rcpt_1 |
PANTHERi | PTHR24062, PTHR24062, 1 hit |
Pfami | View protein in Pfam PF05296, TAS2R, 1 hit |
PROSITEi | View protein in PROSITE PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D3YTX5_MOUSE | |
Accessioni | D3YTX5Primary (citable) accession number: D3YTX5 Secondary accession number(s): D3YTX3 E9Q8U4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | January 9, 2013 | |
Last modified: | December 2, 2020 | |
This is version 85 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |