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UniProtKB - D3GV03 (D3GV03_ECO44)

Entry version 42 (02 Dec 2020)
Sequence version 1 (23 Mar 2010)
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Protein
Submitted name:

Putative type VI secretion protein

Gene

EC042_4576

Organism
Escherichia coli O44:H18 (strain 042 / EAEC)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative type VI secretion proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:EC042_4576Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli O44:H18 (strain 042 / EAEC)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri216592 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001407 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 34HelicalSequence analysisAdd BLAST23
Transmembranei40 – 64HelicalSequence analysisAdd BLAST25

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini177 – 344IcmF-related_NInterPro annotationAdd BLAST168

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili936 – 956Sequence analysisAdd BLAST21
Coiled coili1082 – 1112Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_008769_0_0_6

Identification of Orthologs from Complete Genome Data

More...OMAi		APTEDCD

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR025743, IcmF-related_N_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14331, IcmF-related_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D3GV03-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIFMLKKTFS LFLWFFVSVF VLSVCYVIGV FRNWTDTTTA LYWISVILVT 
        60         70         80         90        100
LSFKFIMDCI HNYFSAGKYR NFLKSFSRKK RALTLDSYFK KGLNIISKRG 
       110        120        130        140        150
RGEVPWFLLT GDSEKNNSLL EDINLPVFHR NCVNSTPQQF RTIRWWFFRD 
       160        170        180        190        200
LSVLELSGKI YDNPGVINSV ISSLSARKCK KQPPRGVVLV ISADKLINHD 
       210        220        230        240        250
YTYIRTLSQK TRSFVEQLSL HLHHNIPVFI VISGCEHISG YSVLAQKIYQ 
       260        270        280        290        300
KHEKWHPVFW ATNKSGTNAS EYDSSYILSS LRSNIMASIC HALDDSLSDK 
       310        320        330        340        350
EKNDILQFPD RLKGLKYSLD IFISTFCIEN VFFSQTEIAG ICLSGELMGE 
       360        370        380        390        400
KDKNCIFADI LISEILPQIH DSDVIHVNKQ RVNVSFKSVI AMTALCFVGY 
       410        420        430        440        450
SGYCSYNVYN IRHGSVDTSH AFLTEQISKY EDKVRSNMRY FPFKPALDDK 
       460        470        480        490        500
YLFFRESLHK TTRFDISPVS WRVTEYKKNF MQASPSGKRE LILSLSSSLI 
       510        520        530        540        550
SWDKMMKDES LSDLAKSPGI HELLKITRPH DKISSIASLA VERDEIQKNN 
       560        570        580        590        600
GIENIYVFRN LLTELVQSDP SYSWFVSEDV NIPAVRITDF WEDENSSVYL 
       610        620        630        640        650
SGIWTQPGQN KLHQWYETIK EAYGRDTVPE AFSSFVLYLD ESRQEHFRQF 
       660        670        680        690        700
IMSVARARKD SHSGLMNPLQ LTNIIHNRSS EHRFFQFVDD ELHNIPTSSA 
       710        720        730        740        750
QDWLSEFRLL NHLFSLKVDN GMKRQIEQFD LMLRIYLISV LNNSQMNRTL 
       760        770        780        790        800
THVTTWRSWQ NALRNAVNSV LHTASSVELI RNAMRSDPEN KLVILFDEFE 
       810        820        830        840        850
KVRSVINSNN REPVIDSVWD IYERQIYQLL DHAVTYTGCW VGEQWRNSVL 
       860        870        880        890        900
GRFNSGKHNL SYSEMQGKVY KDIIGFLKGP SNGVLALDPD GVRLLSFRER 
       910        920        930        940        950
SIPFSPSFIT FINDIVSPDD LLDVWLRERT QNKDELINVQ GQLDLLNQTL 
       960        970        980        990       1000
QNAESQPYRV TIDSAPATIP DNPRVKPTGT TLTLECKTGN SSIRSMNFAD 
      1010       1020       1030       1040       1050
SGIFTWYPGS CHSVRIDILF PNFSATYKFT GETAWIDFIN KFSDGESELM 
      1060       1070       1080       1090       1100
TKDFSPESRN FLESMGIKGI LVRYKLSDTG NLSQAYIEWE QLKQEKDKLK 
      1110       1120       1130 
DLQVNLSNKL LTTHSWEKSA WISRLPGNIT ICPVVQE
Length:1,137
Mass (Da):131,133
Last modified:March 23, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i18F1914CF31556EB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
FN554766 Genomic DNA Translation: CBG37397.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		elo:EC042_4576

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|216592.3.peg.4749

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN554766 Genomic DNA Translation: CBG37397.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

KEGGielo:EC042_4576
PATRICifig|216592.3.peg.4749

Phylogenomic databases

HOGENOMiCLU_008769_0_0_6
OMAiAPTEDCD

Family and domain databases

InterProiView protein in InterPro
IPR025743, IcmF-related_N_dom
PfamiView protein in Pfam
PF14331, IcmF-related_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD3GV03_ECO44
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3GV03
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: December 2, 2020
This is version 42 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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