UniProtKB - D3GA35 (D3GA35_RABIT)
Protein
Submitted name:
Myogenin
Gene
myog
Organism
Oryctolagus cuniculus (Rabbit)
Status
Functioni
GO - Molecular functioni
- chromatin DNA binding Source: Ensembl
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- E-box binding Source: Ensembl
- protein dimerization activity Source: InterPro
GO - Biological processi
- cellular response to estradiol stimulus Source: Ensembl
- cellular response to growth factor stimulus Source: Ensembl
- cellular response to lithium ion Source: Ensembl
- cellular response to tumor necrosis factor Source: Ensembl
- negative regulation of cell population proliferation Source: Ensembl
- ossification Source: Ensembl
- positive regulation of cell cycle arrest Source: Ensembl
- positive regulation of muscle atrophy Source: Ensembl
- positive regulation of myoblast differentiation Source: Ensembl
- positive regulation of skeletal muscle fiber development Source: Ensembl
- regulation of myoblast fusion Source: Ensembl
- regulation of skeletal muscle satellite cell proliferation Source: Ensembl
- response to denervation involved in regulation of muscle adaptation Source: Ensembl
- skeletal muscle fiber development Source: Ensembl
- striated muscle atrophy Source: Ensembl
Keywordsi
Molecular function | Developmental proteinARBA annotation, DNA-bindingARBA annotation |
Biological process | DifferentiationARBA annotation, MyogenesisARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: MyogeninImported |
Gene namesi | Name:myogImported Synonyms:MYOGImported |
Organismi | Oryctolagus cuniculus (Rabbit)Imported |
Taxonomic identifieri | 9986 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Lagomorpha › Leporidae › Oryctolagus |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleoplasm Source: Ensembl
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSOCUG00000011548, Expressed in embryo and 5 other tissues |
Interactioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
STRINGi | 9986.ENSOCUP00000009928 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 81 – 132 | BHLHInterPro annotationAdd BLAST | 52 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 122 – 149 | Sequence analysisAdd BLAST | 28 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG3960, Eukaryota |
GeneTreei | ENSGT00950000182959 |
HOGENOMi | CLU_100258_0_0_1 |
OrthoDBi | 1471470at2759 |
TreeFami | TF316344 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR002546, MyoD_N IPR039704, Myogenic_factor |
PANTHERi | PTHR11534, PTHR11534, 1 hit |
Pfami | View protein in Pfam PF01586, Basic, 1 hit PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00520, BASIC, 1 hit SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
D3GA35-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MELYETSPYF YQEPRFYDGE NYLPVHLQGF EPPGYERTEL SLSPEARGPL
60 70 80 90 100
EDKGLGTPEH CPGQCLPWAC KVCKRKSVSV DRRRAATLRE KRRLKKVNEA
110 120 130 140 150
FEALKRSTLL NPNQRLPKVE ILRSAIQYIE RLQALLSSLN QEERDLRYRG
160 170 180 190 200
GAGPQPGQVP SECSSHSASC SPEWGNALEF GPNPGDHMLA ADPTDAHNLH
210 220
SLTSIVDSIA VEDVSVAFPD ETMPN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAGW02025297 Genomic DNA No translation available. FJ605115 Genomic DNA Translation: ACN53836.1 |
Genome annotation databases
Ensembli | ENSOCUT00000011544; ENSOCUP00000009928; ENSOCUG00000011548 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAGW02025297 Genomic DNA No translation available. FJ605115 Genomic DNA Translation: ACN53836.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9986.ENSOCUP00000009928 |
Genome annotation databases
Ensembli | ENSOCUT00000011544; ENSOCUP00000009928; ENSOCUG00000011548 |
Phylogenomic databases
eggNOGi | KOG3960, Eukaryota |
GeneTreei | ENSGT00950000182959 |
HOGENOMi | CLU_100258_0_0_1 |
OrthoDBi | 1471470at2759 |
TreeFami | TF316344 |
Gene expression databases
Bgeei | ENSOCUG00000011548, Expressed in embryo and 5 other tissues |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR002546, MyoD_N IPR039704, Myogenic_factor |
PANTHERi | PTHR11534, PTHR11534, 1 hit |
Pfami | View protein in Pfam PF01586, Basic, 1 hit PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00520, BASIC, 1 hit SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D3GA35_RABIT | |
Accessioni | D3GA35Primary (citable) accession number: D3GA35 Secondary accession number(s): G1T1H8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 23, 2010 |
Last sequence update: | March 23, 2010 | |
Last modified: | December 2, 2020 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |