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Protein
Submitted name:

Cleavage and polyadenylation specific factor 1, 160kDa, isoform CRA_a

Gene

CPSF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Cleavage and polyadenylation specific factor 1, 160kDa, isoform CRA_aImported
Gene namesi
Name:CPSF1Imported
ORF Names:hCG_2039719Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PeptideAtlasiD3DWL9
PRIDEiD3DWL9

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini996 – 1330CPSF_AInterPro annotationAdd BLAST335

Phylogenomic databases

eggNOGiKOG1896 Eukaryota
COG5161 LUCA

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR004871 Cleavage/polyA-sp_fac_asu_C
IPR015943 WD40/YVTN_repeat-like_dom_sf
PfamiView protein in Pfam
PF03178 CPSF_A, 1 hit

Sequencei

Sequence statusi: Complete.

D3DWL9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSMASVQLAG AKRDALLLSF KDAKLSVVEY DPGTHDLKTL SLHYFEEPEL
60 70 80 90 100
RDGFVQNVHT PRVRVDPDGR CAAMLVYGTR LVVLPFRRES LAEEHEGLVG
110 120 130 140 150
EGQRSSFLPS YIIDVRALDE KLLNIIDLQF LHGYYEPTLL ILFEPNQTWP
160 170 180 190 200
GRVAVRQDTC SIVAISLNIT QKVHPVIWSL TSLPFDCTQA LAVPKPIGGV
210 220 230 240 250
VVFAVNSLLY LNQSVPPYGV ALNSLTTGTT AFPLRTQEGV RITLDCAQAT
260 270 280 290 300
FISYDKMVIS LKGGEIYVLT LITDGMRSVR AFHFDKAAAS VLTTSMVTME
310 320 330 340 350
PGYLFLGSRL GNSLLLKYTE KLQEPPASAV REAADKEEPP SKKKRVDATA
360 370 380 390 400
GWSAAGKSVP QDEVDEIEVY GSEAQSGTQL ATYSFEVCDS ILNIGPCANA
410 420 430 440 450
AVGEPAFLSE EFQNSPEPDL EIVVCSGHGK NGALSVLQKS IRPQVVTTFE
460 470 480 490 500
LPGCYDMWTV IAPVRKEEED NPKGEGTEQE PSTTPEADDD GRRHGFLILS
510 520 530 540 550
REDSTMILQT GQEIMELDTS GFATQGPTVF AGNIGDNRYI VQVSPLGIRL
560 570 580 590 600
LEGVNQLHFI PVDLGAPIVQ CAVADPYVVI MSAEGHVTMF LLKSDSYGGR
610 620 630 640 650
HHRLALHKPP LHHQSKVITL CLYRDLSGMF TTESRLGGAR DELGGRSGPE
660 670 680 690 700
AEGLGSETSP TVDDEEEMLY GDSGSLFSPS KEEARRSSQP PADRDPAPFR
710 720 730 740 750
AEPTHWCLLV RENGTMEIYQ LPDWRLVFLV KNFPVGQRVL VDSSFGQPTT
760 770 780 790 800
QGEARREEAT RQGELPLVKE VLLVALGSRQ SRPYLLVHVD QELLIYEAFP
810 820 830 840 850
HDSQLGQGNL KVRFKKVPHN INFREKKPKP SKKKAEGGGA EEGAGARGRV
860 870 880 890 900
ARFRYFEDIY GYSGVFICGP SPHWLLVTGR GALRLHPMAI DGPVDSFAPF
910 920 930 940 950
HNVNCPRGFL YFNRQGELRI SVLPAYLSYD APWPVRKIPL RCTAHYVAYH
960 970 980 990 1000
VESKVYAVAT STNTPCARIP RMTGEEKEFE TIERDERYIH PQQEAFSIQL
1010 1020 1030 1040 1050
ISPVSWEAIP NARIELQEWE HVTCMKTVSL RSEETVSGLK GYVAAGTCLM
1060 1070 1080 1090 1100
QGEEVTCRGR ILIMDVIEVV PEPGQPLTKN KFKVLYEKEQ KGPVTALCHC
1110 1120 1130 1140 1150
NGHLVSAIGQ KIFLWSLRAS ELTGMAFIDT QLYIHQMISV KNFILAADVM
1160 1170 1180 1190 1200
KSISLLRYQE ESKTLSLVSR DAKPLEVYSV DFMVDNAQLG FLVSDRDRNL
1210 1220 1230 1240 1250
MVYMYLPEAK ESFGGMRLLR RADFHVGAHV NTFWRTPCRG ATEGLSKKSV
1260 1270 1280 1290 1300
VWENKHITWF ATLDGGIGLL LPMQEKTYRR LLMLQNALTT MLPHHAGLNP
1310 1320 1330 1340 1350
RAFRMLHVDR RTLQNAVRNV LDGELLNRYL YLSTMERSEL AKKIGTTPDI
1360
ILDDLLETDR VTAHF
Length:1,365
Mass (Da):151,986
Last modified:March 23, 2010 - v1
Checksum:i6B2687215CDB51BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471162 Genomic DNA Translation: EAW82106.1
CH471162 Genomic DNA Translation: EAW82107.1
CH471162 Genomic DNA Translation: EAW82108.1
RefSeqiXP_006716612.1, XM_006716549.2
XP_011515299.1, XM_011516997.1
XP_011515300.1, XM_011516998.1
XP_011515301.1, XM_011516999.1
UniGeneiHs.493202

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471162 Genomic DNA Translation: EAW82106.1
CH471162 Genomic DNA Translation: EAW82107.1
CH471162 Genomic DNA Translation: EAW82108.1
RefSeqiXP_006716612.1, XM_006716549.2
XP_011515299.1, XM_011516997.1
XP_011515300.1, XM_011516998.1
XP_011515301.1, XM_011516999.1
UniGeneiHs.493202

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiD3DWL9
PRIDEiD3DWL9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1896 Eukaryota
COG5161 LUCA

Miscellaneous databases

ChiTaRSiCPSF1 human
GenomeRNAii29894

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR004871 Cleavage/polyA-sp_fac_asu_C
IPR015943 WD40/YVTN_repeat-like_dom_sf
PfamiView protein in Pfam
PF03178 CPSF_A, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3DWL9_HUMAN
AccessioniPrimary (citable) accession number: D3DWL9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: September 12, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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