UniProtKB - D3DUX0 (D3DUX0_HUMAN)
Protein
Submitted name:
Nik related kinase, isoform CRA_a
Gene
NRK
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protein kinase activity Source: InterPro
Keywordsi
Molecular function | KinaseImported, Transferase |
Ligand | ATP-bindingARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Nik related kinase, isoform CRA_aImported |
Gene namesi | Name:NRKImported ORF Names:hCG_1810772Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 25 – 307 | Protein kinaseInterPro annotationAdd BLAST | 283 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 486 – 573 | DisorderedSequence analysisAdd BLAST | 88 | |
Regioni | 777 – 797 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 812 – 841 | DisorderedSequence analysisAdd BLAST | 30 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 729 – 749 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 486 – 508 | PolarSequence analysisAdd BLAST | 23 | |
Compositional biasi | 516 – 554 | PolarSequence analysisAdd BLAST | 39 | |
Compositional biasi | 777 – 792 | PolarSequence analysisAdd BLAST | 16 | |
Compositional biasi | 816 – 832 | PolarSequence analysisAdd BLAST | 17 |
Keywords - Domaini
Coiled coilSequence analysisFamily and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
D3DUX0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGPGGWRDR EVTDLGHLPD PTGIFSLDKT IGLGTYGRIY LGLHEKTGAF
60 70 80 90 100
TAVKVMNARK TPLPEIGRRV RVNKYQKSDE EEDLRTELNL LRKYSFHKNI
110 120 130 140 150
VSFYGAFFKL SPPGQRHQLW MVMELCAAGS VTDVVRMTSN QSLKEDWIAY
160 170 180 190 200
ICREILQGLA HLHAHRVIHR DIKGQNVLLT HNAEVKLVDF GVSAQVSRTN
210 220 230 240 250
GRRNSFIGTP YWMAPEVIDC DEDPRRSYDY RSDVWSVGIT AIEMAEGAPP
260 270 280 290 300
LCNLQPLEAL FVILRESAPT VKSSGWSRKF HNFMEKCTIK NFLFRPTSAN
310 320 330 340 350
MLQHPFVRDI KNERHVVESL TRHLTGIIKK RQKKGIPLIF EREEAIKEQY
360 370 380 390 400
TVRRFRGPSC THELLRLPTS SRCRPLRVLH GEPSQPRWLP DREEPQVQAL
410 420 430 440 450
QQLQGAARVF MPLQALDSAP KPLKGQAQAP QRLQGAARVF MPLQAQVKAK
460 470 480 490 500
ASKPLQMQIK APPRLRRAAR VLMPLQAQVR APRLLQVQSQ VSKKQQAQTQ
510 520 530 540 550
TSEPQDLDQV PEEFQGQDQV PEQQRQGQAP EQQQRHNQVP EQELEQNQAP
560 570 580 590 600
EQPEVQEQAA EPAQAETEAE EPESLRVNAQ VFLPLLSQDH HVLLPLHLDT
610 620 630 640 650
QVLIPVEGQT EGSPQAQAWT LEPPQAIGSV QALIEGLSRD LLRAPNSNNS
660 670 680 690 700
KPLGPLQTLM ENLSSNRFYS QPEQAREKKS KVSTLRQALA KRLSPKRFRA
710 720 730 740 750
KSSWRPEKLE LSDLEARRQR RQRRWEDIFN QHEEELRQVD KDKEDESSDN
760 770 780 790 800
DEVFHSIQAE VQIEPLKPYI SNPKKIEVQE RSPSVPNNQD HAHHVKFSSR
810 820 830 840
YVVPQRSLLE QAQKPIDIRQ RSSQNRQNWL AASGDSKKKV L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471120 Genomic DNA Translation: EAX02749.1 CH471120 Genomic DNA Translation: EAX02750.1 |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471120 Genomic DNA Translation: EAX02749.1 CH471120 Genomic DNA Translation: EAX02750.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | D3DUX0 |
Miscellaneous databases
ChiTaRSi | NRK, human |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D3DUX0_HUMAN | |
Accessioni | D3DUX0Primary (citable) accession number: D3DUX0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 23, 2010 |
Last sequence update: | March 23, 2010 | |
Last modified: | October 7, 2020 | |
This is version 58 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |