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Protein
Submitted name:

Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b

Gene

FGFR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, ReceptorImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_bImported
Gene namesi
Name:FGFR1Imported
ORF Names:hCG_23105Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiD3DSX2
PRIDEiD3DSX2

Structurei

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 331Protein kinaseInterPro annotationAdd BLAST290

Sequence similaritiesi

Belongs to the protein kinase superfamily. Tyr protein kinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0200 Eukaryota
COG0515 LUCA
HOGENOMiHOG000263410

Family and domain databases

CDDicd05098 PTKc_FGFR1, 1 hit
InterProiView protein in InterPro
IPR028174 FGF_rcpt_1
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008266 Tyr_kinase_AS
IPR020635 Tyr_kinase_cat_dom
PfamiView protein in Pfam
PF07714 Pkinase_Tyr, 1 hit
PRINTSiPR00109 TYRKINASE
SMARTiView protein in SMART
SM00219 TyrKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit

Sequencei

Sequence statusi: Complete.

D3DSX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSGVLLVRP SRLSSSGTPM LAGVSEYELP EDPRWELPRD RLVLGKPLGE
60 70 80 90 100
GCFGQVVLAE AIGLDKDKPN RVTKVAVKML KSDATEKDLS DLISEMEMMK
110 120 130 140 150
MIGKHKNIIN LLGACTQDGP LYVIVEYASK GNLREYLQAR RPPGLEYCYN
160 170 180 190 200
PSHNPEEQLS SKDLVSCAYQ VARGMEYLAS KKCIHRDLAA RNVLVTEDNV
210 220 230 240 250
MKIADFGLAR DIHHIDYYKK TTNGRLPVKW MAPEALFDRI YTHQSDVWSF
260 270 280 290 300
GVLLWEIFTL GGSPYPGVPV EELFKLLKEG HRMDKPSNCT NELYMMMRDC
310 320 330 340 350
WHAVPSQRPT FKQLVEDLDR IVALTSNQEY LDLSMPLDQY SPSFPDTRSS
360 370 380
TCSSGEDSVF SHEPLPEEPC LPRHPAQLAN GGLKRR
Length:386
Mass (Da):43,564
Last modified:March 23, 2010 - v1
Checksum:i3500FCCA3C4FD207
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471080 Genomic DNA Translation: EAW63304.1
CH471080 Genomic DNA Translation: EAW63313.1
CH471080 Genomic DNA Translation: EAW63316.1
UniGeneiHs.264887

Similar proteinsi

Entry informationi

Entry nameiD3DSX2_HUMAN
AccessioniPrimary (citable) accession number: D3DSX2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 23, 2010
Last sequence update: March 23, 2010
Last modified: July 18, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

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