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Entry version 47 (07 Apr 2021)
Sequence version 1 (02 Mar 2010)
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Protein
Submitted name:

ATP-binding cassette transporter 1

Gene

ABC1

Organism
Rhizophagus irregularis (Arbuscular mycorrhizal fungus) (Glomus intraradices)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi646 – 653ATPPROSITE-ProRule annotation8
Nucleotide bindingi1293 – 1300ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.1.208.32, the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ATP-binding cassette transporter 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABC1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRhizophagus irregularis (Arbuscular mycorrhizal fungus) (Glomus intraradices)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4876 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiFungi incertae sedisMucoromycotaGlomeromycotinaGlomeromycetesGlomeralesGlomeraceaeRhizophagus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei31 – 49HelicalSequence analysisAdd BLAST19
Transmembranei70 – 92HelicalSequence analysisAdd BLAST23
Transmembranei98 – 119HelicalSequence analysisAdd BLAST22
Transmembranei131 – 149HelicalSequence analysisAdd BLAST19
Transmembranei161 – 182HelicalSequence analysisAdd BLAST22
Transmembranei264 – 282HelicalSequence analysisAdd BLAST19
Transmembranei317 – 341HelicalSequence analysisAdd BLAST25
Transmembranei393 – 414HelicalSequence analysisAdd BLAST22
Transmembranei420 – 439HelicalSequence analysisAdd BLAST20
Transmembranei518 – 538HelicalSequence analysisAdd BLAST21
Transmembranei558 – 579HelicalSequence analysisAdd BLAST22
Transmembranei931 – 954HelicalSequence analysisAdd BLAST24
Transmembranei974 – 1005HelicalSequence analysisAdd BLAST32
Transmembranei1049 – 1071HelicalSequence analysisAdd BLAST23
Transmembranei1077 – 1097HelicalSequence analysisAdd BLAST21
Transmembranei1168 – 1187HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini277 – 574ABC transmembrane type-1InterPro annotationAdd BLAST298
Domaini612 – 836ABC transporterInterPro annotationAdd BLAST225
Domaini945 – 1222ABC transmembrane type-1InterPro annotationAdd BLAST278
Domaini1259 – 1493ABC transporterInterPro annotationAdd BLAST235

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR011527, ABC1_TM_dom
IPR036640, ABC1_TM_sf
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664, ABC_membrane, 2 hits
PF00005, ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits
SSF90123, SSF90123, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929, ABC_TM1F, 2 hits
PS00211, ABC_TRANSPORTER_1, 2 hits
PS50893, ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D2WF19-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLCRDKDGWG PWRPDLPNQQ FPDFTDCFEE GVILTSVNLL LIVLGFYEIR
60 70 80 90 100
RYSKKHAVLP LHALNNWHNI AITITLYLLI ALSIINFVST LWSDWQLLNI
110 120 130 140 150
MVISSFINLF TMFVAYSVYK KSYTHSHVSS PVLLLYWLFY LIAHILKLRT
160 170 180 190 200
LVLMGYASKP FYFFTTLFST ILVLVVFVLE LLPKPQSDYE LINGDDNLNC
210 220 230 240 250
PEESANIFSR STFYWMTPLM KLGHQKFLTM DDLWNLDPQY RSKKISEDFD
260 270 280 290 300
VAWNKELKKK NPSLLRAITL TFGGQFAFAA AFKAVQDILN FVQPQLLGEL
310 320 330 340 350
MEFVNSQRDR ETSQPAYRGY CIAILMFVTA VIQTMFLHQY FQLCFISGMR
360 370 380 390 400
VKAALVTAIY QKAFKLSNTS RQKSTVGEIV NHMSVDAQEL MDLFTYLHIA
410 420 430 440 450
WSGPLQIILA LYFLHQTMGV STYAGVGIMI MMVPVNAYLA NKMKILQKKQ
460 470 480 490 500
MKNKDERIKL MVSLYNEILN GIKVIKLYAW EQAFLKKVRN DLELKTLKRL
510 520 530 540 550
GYLYAVQSFT WTSTVSHLFP IFTPFLVSFA TFAVYVLISN SPLTVQVVFV
560 570 580 590 600
AIPLFNLLQF PLAVFPSVIT SIIEASVALR RVEEYLTSEE LDPKAVIRQG
610 620 630 640 650
YYDTEDERSE LVPVKNGTFG WGNSGEAVLE DINLSVKKGE LVAIVGKVGA
660 670 680 690 700
GKSSLLSSLL GEMEKIGGEV IVKGHVAYVH QTPWIMNATL RDNITFGYEY
710 720 730 740 750
KPELYDEIIE ACALKPDIAI LPGGDLTEIG EKGINLSGGQ KARVALARAV
760 770 780 790 800
YARADVYLFD DTLSAVDAHV GKHIFDKVVG SNGILRTKAR IFVTHGIHYL
810 820 830 840 850
SKTDSVVMMR DGKIIEQGHF DSLMKLKSEL FNLIDEFGQQ EESNNLLDDE
860 870 880 890 900
PPDDPEELMP LAYETDEVAT DQRSEETVSQ LRERRVSVPS IHRRASTATV
910 920 930 940 950
KNESKREQQK NELITKEEMA KGSVSWQVYS SYLKSCGVVT ITFWIITLVI
960 970 980 990 1000
SQGIQVATNV FLKYWSSEES NERILLYFVI YGLLGLLFSL MVIFQTIVLW
1010 1020 1030 1040 1050
VFCFFRAARK LHHQMLDGVI RSPMSFFDTT PLGRILNRFS KDIYTIDELL
1060 1070 1080 1090 1100
PRIFAGYFRT FFVVLSTIFV ISFSTPLFII LIIPMTFMYI YIQTYYLSTS
1110 1120 1130 1140 1150
RELKRLDSVT RSPIYAHFQE TLGGLTTIRA FQQMNRFIRD NETKLDVNQK
1160 1170 1180 1190 1200
AYFPSFSSNR WLAVRLEFLG SIIIFGAAIF SVISVLTTGN IDAGLVGLSV
1210 1220 1230 1240 1250
SYALSVTQAL NWAVRQFCEI ETNIVSVERV KEYIDLPSEA PVVIQDNRPD
1260 1270 1280 1290 1300
PTWPQNGLIE YQNYSTRYRQ GLELVLKGVS FVINPREKVG IVGRTGAGKS
1310 1320 1330 1340 1350
SLTLSLFRLI EAVDGAILMD GVDISKIGLY DLRSRLTIIP QDPILFEGTV
1360 1370 1380 1390 1400
EFNLDPFETH DEVEIWQALQ SAHLKDYISK LEGKLHAKIL EGGDNFSQGQ
1410 1420 1430 1440 1450
RQLLCLARAL LRRSNIIVLD EATACVDVET DFQIQNTIRN EFNWATLLCI
1460 1470 1480 1490 1500
AHRLRTIIDY DRVLVLDEGN VVEFDTPYNL LQNPNSLFYK LCEQSNEFDY
1510
LKDLATKNHS PKR
Length:1,513
Mass (Da):172,430
Last modified:March 2, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB6CB534F90294013
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GQ249346 mRNA Translation: ADB03433.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ249346 mRNA Translation: ADB03433.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

TCDBi3.A.1.208.32, the atp-binding cassette (abc) superfamily

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR011527, ABC1_TM_dom
IPR036640, ABC1_TM_sf
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00664, ABC_membrane, 2 hits
PF00005, ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SUPFAMiSSF52540, SSF52540, 2 hits
SSF90123, SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929, ABC_TM1F, 2 hits
PS00211, ABC_TRANSPORTER_1, 2 hits
PS50893, ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD2WF19_RHIIR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D2WF19
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: April 7, 2021
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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