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Entry version 81 (12 Aug 2020)
Sequence version 1 (02 Mar 2010)
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Protein
Submitted name:

Neurogenic locus notch homolog protein 2

Gene

NOTCH2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Neurogenic locus notch homolog protein 2Imported
Submitted name:
Neurogenic locus notch-like protein 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NOTCH2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000134250.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7882, NOTCH2

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000134250

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi14 ↔ 23PROSITE-ProRule annotation
Disulfide bondi34 ↔ 51PROSITE-ProRule annotation
Disulfide bondi53 ↔ 62PROSITE-ProRule annotation
Disulfide bondi94 ↔ 103PROSITE-ProRule annotation
Disulfide bondi131 ↔ 140PROSITE-ProRule annotation
Disulfide bondi170 ↔ 179PROSITE-ProRule annotation
Disulfide bondi209 ↔ 218PROSITE-ProRule annotation
Disulfide bondi247 ↔ 256PROSITE-ProRule annotation
Disulfide bondi287 ↔ 296PROSITE-ProRule annotation
Disulfide bondi325 ↔ 334PROSITE-ProRule annotation
Disulfide bondi345 ↔ 362PROSITE-ProRule annotation
Disulfide bondi364 ↔ 373PROSITE-ProRule annotation
Disulfide bondi405 ↔ 414PROSITE-ProRule annotation
Disulfide bondi443 ↔ 452PROSITE-ProRule annotation
Disulfide bondi481 ↔ 490PROSITE-ProRule annotation
Disulfide bondi519 ↔ 528PROSITE-ProRule annotation
Disulfide bondi535 ↔ 545PROSITE-ProRule annotation
Disulfide bondi556 ↔ 565PROSITE-ProRule annotation
Disulfide bondi594 ↔ 603PROSITE-ProRule annotation
Disulfide bondi610 ↔ 620PROSITE-ProRule annotation
Disulfide bondi631 ↔ 640PROSITE-ProRule annotation
Disulfide bondi669 ↔ 678PROSITE-ProRule annotation
Disulfide bondi685 ↔ 695PROSITE-ProRule annotation
Disulfide bondi706 ↔ 715PROSITE-ProRule annotation
Disulfide bondi744 ↔ 753PROSITE-ProRule annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

Proteomic databases

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
12736

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000134250, Expressed in testis and 248 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
D2WEZ3, baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 24EGF-likeInterPro annotationAdd BLAST24
Domaini25 – 63EGF-likeInterPro annotationAdd BLAST39
Domaini66 – 104EGF-likeInterPro annotationAdd BLAST39
Domaini105 – 141EGF-likeInterPro annotationAdd BLAST37
Domaini143 – 180EGF-likeInterPro annotationAdd BLAST38
Domaini182 – 219EGF-likeInterPro annotationAdd BLAST38
Domaini221 – 257EGF-likeInterPro annotationAdd BLAST37
Domaini259 – 297EGF-likeInterPro annotationAdd BLAST39
Domaini299 – 335EGF-likeInterPro annotationAdd BLAST37
Domaini336 – 374EGF-likeInterPro annotationAdd BLAST39
Domaini376 – 415EGF-likeInterPro annotationAdd BLAST40
Domaini417 – 453EGF-likeInterPro annotationAdd BLAST37
Domaini455 – 491EGF-likeInterPro annotationAdd BLAST37
Domaini493 – 529EGF-likeInterPro annotationAdd BLAST37
Domaini531 – 566EGF-likeInterPro annotationAdd BLAST36
Domaini568 – 604EGF-likeInterPro annotationAdd BLAST37
Domaini606 – 641EGF-likeInterPro annotationAdd BLAST36
Domaini643 – 679EGF-likeInterPro annotationAdd BLAST37
Domaini681 – 716EGF-likeInterPro annotationAdd BLAST36
Domaini718 – 754EGF-likeInterPro annotationAdd BLAST37
Domaini756 – 789EGF-likeInterPro annotationAdd BLAST34

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation, SignalARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155030

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004826_12_0_1

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001881, EGF-like_Ca-bd_dom
IPR013032, EGF-like_CS
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR009030, Growth_fac_rcpt_cys_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00008, EGF, 13 hits
PF07645, EGF_CA, 3 hits
PF12661, hEGF, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 20 hits
SM00179, EGF_CA, 20 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57184, SSF57184, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00010, ASX_HYDROXYL, 14 hits
PS00022, EGF_1, 19 hits
PS01186, EGF_2, 16 hits
PS50026, EGF_3, 21 hits
PS01187, EGF_CA, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

D2WEZ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCVTYHNGTG YCKCPEGFLG EYCQHRDPCE KNRCQNGGTC VAQAMLGKAT
60 70 80 90 100
CRCASGFTGE DCQYSTSHPC FVSRPCLNGG TCHMLSRDTY ECTCQVGFTG
110 120 130 140 150
KECQWTDACL SHPCANGSTC TTVANQFSCK CLTGFTGQKC ETDVNECDIP
160 170 180 190 200
GHCQHGGTCL NLPGSYQCQC PQGFTGQYCD SLYVPCAPSP CVNGGTCRQT
210 220 230 240 250
GDFTFECNCL PGFEGSTCER NIDDCPNHRC QNGGVCVDGV NTYNCRCPPQ
260 270 280 290 300
WTGQFCTEDV DECLLQPNAC QNGGTCANRN GGYGCVCVNG WSGDDCSENI
310 320 330 340 350
DDCAFASCTP GSTCIDRVAS FSCMCPEGKA GLLCHLDDAC ISNPCHKGAL
360 370 380 390 400
CDTNPLNGQY ICTCPQGYKG ADCTEDVDEC AMANSNPCEH AGKCVNTDGA
410 420 430 440 450
FHCECLKGYA GPRCEMDINE CHSDPCQNDA TCLDKIGGFT CLCMPGFKGV
460 470 480 490 500
HCELEINECQ SNPCVNNGQC VDKVNRFQCL CPPGFTGPVC QIDIDDCSST
510 520 530 540 550
PCLNGAKCID HPNGYECQCA TGFTGVLCEE NIDNCDPDPC HHGQCQDGID
560 570 580 590 600
SYTCICNPGY MGAICSDQID ECYSSPCLND GRCIDLVNGY QCNCQPGTSG
610 620 630 640 650
VNCEINFDDC ASNPCIHGIC MDGINRYSCV CSPGFTGQRC NIDIDECASN
660 670 680 690 700
PCRKGATCIN GVNGFRCICP EGPHHPSCYS QVNECLSNPC IHGNCTGGLS
710 720 730 740 750
GYKCLCDAGW VGINCEVDKN ECLSNPCQNG GTCDNLVNGY RCTCKKGFKG
760 770 780 790 800
YNCQVNIDEC ASNPCLNQGT CFDDISGYTC HCVLPYTGGS WRYQQGPEGI
810 820 830 840 850
LDLALSVPES QCPGLWGCNA PPRAHSSVVL PAFTDWILSF EETLWPPKMQ
860
VVDSHLPTLY FSI
Length:863
Mass (Da):92,575
Last modified:March 2, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE06411F81F03E6C8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q04721NOTC2_HUMAN
Neurogenic locus notch homolog prot...
NOTCH2
2,471Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C1U9A0A494C1U9_HUMAN
Neurogenic locus notch homolog prot...
NOTCH2
274Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C1F1A0A494C1F1_HUMAN
Neurogenic locus notch homolog prot...
NOTCH2
114Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
R4GN02R4GN02_HUMAN
Neurogenic locus notch homolog prot...
NOTCH2
236Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2PQQ5A0A1W2PQQ5_HUMAN
Neurogenic locus notch homolog prot...
NOTCH2
31Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C1H8A0A494C1H8_HUMAN
Neurogenic locus notch homolog prot...
NOTCH2
12Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C049A0A494C049_HUMAN
Neurogenic locus notch homolog prot...
NOTCH2
25Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC245008 Genomic DNA No translation available.
AL359752 Genomic DNA No translation available.
AL512503 Genomic DNA No translation available.
GQ231534 mRNA Translation: ADB12482.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000579475; ENSP00000477065; ENSG00000134250

UCSC genome browser

More...
UCSCi
uc057jwc.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC245008 Genomic DNA No translation available.
AL359752 Genomic DNA No translation available.
AL512503 Genomic DNA No translation available.
GQ231534 mRNA Translation: ADB12482.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

ProteomicsDBi12736

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
20208, 617 antibodies

Genome annotation databases

EnsembliENST00000579475; ENSP00000477065; ENSG00000134250
UCSCiuc057jwc.1, human

Organism-specific databases

EuPathDBiHostDB:ENSG00000134250.17
HGNCiHGNC:7882, NOTCH2
OpenTargetsiENSG00000134250

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000155030
HOGENOMiCLU_004826_12_0_1

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
NOTCH2, human

Gene expression databases

BgeeiENSG00000134250, Expressed in testis and 248 other tissues
ExpressionAtlasiD2WEZ3, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001881, EGF-like_Ca-bd_dom
IPR013032, EGF-like_CS
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR009030, Growth_fac_rcpt_cys_sf
PfamiView protein in Pfam
PF00008, EGF, 13 hits
PF07645, EGF_CA, 3 hits
PF12661, hEGF, 4 hits
SMARTiView protein in SMART
SM00181, EGF, 20 hits
SM00179, EGF_CA, 20 hits
SUPFAMiSSF57184, SSF57184, 3 hits
PROSITEiView protein in PROSITE
PS00010, ASX_HYDROXYL, 14 hits
PS00022, EGF_1, 19 hits
PS01186, EGF_2, 16 hits
PS50026, EGF_3, 21 hits
PS01187, EGF_CA, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD2WEZ3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D2WEZ3
Secondary accession number(s): A0A075B7G9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: August 12, 2020
This is version 81 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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