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Protein

Peptidyl-prolyl cis-trans isomerase

Gene

NAEGRDRAFT_38007

Organism
Naegleria gruberi (Amoeba)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.UniRule annotation

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, RotamaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)
Short name:
PPIaseUniRule annotation
Gene namesi
ORF Names:NAEGRDRAFT_38007Imported
OrganismiNaegleria gruberi (Amoeba)Imported
Taxonomic identifieri5762 [NCBI]
Taxonomic lineageiEukaryotaHeteroloboseaSchizopyrenidaVahlkampfiidaeNaegleria
Proteomesi
  • UP000006671 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi5762.XP_002681260.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 174PPIase cyclophilin-typeInterPro annotationAdd BLAST157

Sequence similaritiesi

Belongs to the cyclophilin-type PPIase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0880 Eukaryota
ENOG410Z0G4 LUCA
InParanoidiD2V4H1
OMAiTGRIVMG

Family and domain databases

Gene3Di2.40.100.10, 1 hit
InterProiView protein in InterPro
IPR029000 Cyclophilin-like_dom_sf
IPR024936 Cyclophilin-type_PPIase
IPR020892 Cyclophilin-type_PPIase_CS
IPR002130 Cyclophilin-type_PPIase_dom
PANTHERiPTHR11071 PTHR11071, 1 hit
PfamiView protein in Pfam
PF00160 Pro_isomerase, 1 hit
PIRSFiPIRSF001467 Peptidylpro_ismrse, 1 hit
PRINTSiPR00153 CSAPPISMRASE
SUPFAMiSSF50891 SSF50891, 1 hit
PROSITEiView protein in PROSITE
PS00170 CSA_PPIASE_1, 1 hit
PS50072 CSA_PPIASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

D2V4H1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMVALVKADD KEITDKVYFD ITIGGIPAGR IVFGLYGKTV PKTAENFKQL
60 70 80 90 100
TAGTPGFGYK GSTFHRVITN FVIQGGDFTM GNGMGGKSIY GDRFVDENFK
110 120 130 140 150
VKHFIGCLSM ANAGPDTNGS QFFVTLGPTP WLDGKHVVFG QVVSGLDVVR
160 170
KIENVRTGYG DKPAEEVKVI DSGIVVEEQ
Length:179
Mass (Da):19,333
Last modified:March 2, 2010 - v1
Checksum:i762435249F4893F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG738851 Genomic DNA Translation: EFC48516.1

Genome annotation databases

EnsemblProtistsiEFC48516; EFC48516; NAEGRDRAFT_38007

Similar proteinsi

Entry informationi

Entry nameiD2V4H1_NAEGR
AccessioniPrimary (citable) accession number: D2V4H1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: July 18, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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