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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei53NucleophileUniRule annotation1
Binding sitei111SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processtRNA processingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciKFLA479435:G1GG1-6084-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:Kfla_6098Imported
OrganismiKribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)Imported
Taxonomic identifieri479435 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPropionibacterialesNocardioidaceaeKribbella
Proteomesi
  • UP000007967 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi479435.Kfla_6098

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini145 – 247PseudoU_synth_1InterPro annotationAdd BLAST103

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DI7 Bacteria
COG0101 LUCA
HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 1 hit
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

D2PU50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRWRIDLRYD GTEFHGWARQ DGLRTVQGAL EEALGTVLRL PDRPAVTCAG
60 70 80 90 100
RTDTGVHARG QVTHVDLDVP VTGRDLLRRL NGVLPDDVAV TAVAEAADGF
110 120 130 140 150
DARFSALARR YVYRLCDDAV GWDPLRRREV LRVVRPLDVD RMNAAAAQLL
160 170 180 190 200
GEHDFAAFCK KREGASTVRA LLEYSWVRVG PGLLDGTVIA DAFCHSMVRA
210 220 230 240 250
LVGALIPVGD GRRDVDWPAA VLAGKMRDSA VAVLPAHGLT LEEVRYPADE
260 270
DLAARALLAR QVRGEVHRRG
Length:270
Mass (Da):29,614
Last modified:March 2, 2010 - v1
Checksum:i8DB8E378C754909B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001736 Genomic DNA Translation: ADB35101.1
RefSeqiWP_012923655.1, NC_013729.1

Genome annotation databases

EnsemblBacteriaiADB35101; ADB35101; Kfla_6098
KEGGikfl:Kfla_6098

Similar proteinsi

Entry informationi

Entry nameiD2PU50_KRIFD
AccessioniPrimary (citable) accession number: D2PU50
Entry historyiIntegrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: July 18, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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