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Entry version 28 (31 Jul 2019)
Sequence version 1 (09 Feb 2010)
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Protein
Submitted name:

AnkA

Gene

ankA

Organism
Anaplasma phagocytophilum (Ehrlichia phagocytophila)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferaseImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AnkAImported
Submitted name:
Phosphocholine transferase AnkXImported (EC:2.7.1.-Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ankAImported
Synonyms:ankXImported
ORF Names:ANAPH2_00140Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnaplasma phagocytophilum (Ehrlichia phagocytophila)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri948 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeAnaplasmaphagocytophilum group

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini44 – 868ANK_REP_REGIONInterPro annotationAdd BLAST825
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati44 – 76ANKPROSITE-ProRule annotationAdd BLAST33
Repeati216 – 248ANKPROSITE-ProRule annotationAdd BLAST33
Repeati672 – 712ANKPROSITE-ProRule annotationAdd BLAST41
Repeati713 – 745ANKPROSITE-ProRule annotationAdd BLAST33
Repeati827 – 859ANKPROSITE-ProRule annotationAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni969 – 1128DisorderedSequence analysisAdd BLAST160
Regioni1141 – 1189DisorderedSequence analysisAdd BLAST49

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi983 – 1000PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1029 – 1044PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1065 – 1097PolarSequence analysisAdd BLAST33

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D2KNN0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLTEEEKKKS ACALQAIITG DYDSFQASIQ GISSEGLNTP VDKEGRTLLH
60 70 80 90 100
YAASSRNGNF YGILVERGCV TNLKDAYGFT PEQARKKAGH ARTQWYGADV
110 120 130 140 150
NDPGVSRQLM TQAVQQSAKG NMYGALAILD LVRNDDANIQ INEKGHGVLH
160 170 180 190 200
LACIKGSDPS FTSSLMLKGC SLNIKDVDGN TPLHTAVTSV GRNALGNLDV
210 220 230 240 250
LCDKALIADV NAKGPGGNTP LHIATERMDH QKVDHLLSRL GDISIANDAG
260 270 280 290 300
ETVCHIVAKQ WPRRDVLPYI DKMQEAVSSN IEGNRECAEA LIFPDKKGMS
310 320 330 340 350
AVQYAIRRHI PEAEKIFENA INTADKVYGS ASPEVKSLFT CPNPEDASTL
360 370 380 390 400
VHFVSSNGTP NFDPLAKRVL EEAYHRYGGE PFTNLDIAGN APIHAAAQRS
410 420 430 440 450
TVAVFEQLAR YTPESVVNQL APNGKAPIHM IVEDEPSHKG VSVKLQMLIE
460 470 480 490 500
NVRNIPSINV PSPVTGETPV VAAYKGGNTE DVKTMLRCNS MDVDAQSHDG
510 520 530 540 550
KTIIHHAAKD GNLEILQQAL GRKSSYSKFP VKDGVPTPGV YAIREASDGK
560 570 580 590 600
KVSLPALDML MSYEPHPQHV AVEAVRKGAA DVLRHFITTE VIRVNEEITT
610 620 630 640 650
PEGKKTTLTA EALTNGQYAA VKTLIKNRAD VNTSPEPAIS AGIQGGCFQG
660 670 680 690 700
GKAIKHLKRV VEAGAHINTP PGSMSPLAAA VQSANEASNP KAANRIVNFL
710 720 730 740 750
LQRGADLSST DHIGTPALHL ATAAGNHKTA KLLLDKGAPA TQRDAYGKTA
760 770 780 790 800
LHIAAANGDG KLYKLIAKKC PDSCRPLSSH MGDTALHEAL YSDKVTEKCF
810 820 830 840 850
LKMLKESRKH LSDSSFKDLL NTPQEANGDT LLHLAASRGF GKACKVLLKA
860 870 880 890 900
GASVSVVNVE GKTPVDVADP SLKARPWLFG KSVVTMMAER VQVPEGGFPP
910 920 930 940 950
YLPPESPTPS LGSISSFDSV TVLSSLGSGL DTAGPEESIY EEIKDTAKGA
960 970 980 990 1000
TGVESIYATV GAAITSEAQA SDAASSKGER PESIYADPFD IVKPRQERPE
1010 1020 1030 1040 1050
SIYADPFAAE RTSSSGLTTF GPKEEPIYAT VKKGPKKSDT SQKEGTASEK
1060 1070 1080 1090 1100
VSPTITVMKK KVKPQVPTRT SSLPTKEGIG SDKDLSSGTS SSFAAELQAQ
1110 1120 1130 1140 1150
RGKLRPVKGG APDSTKDKTA TSVFSSEEFK KELTKAAEGL QGAVEAQKGD
1160 1170 1180
GGAAKAKQDL GMESGAPGSQ PEAPQSEGPK SVKGGGRGR
Length:1,189
Mass (Da):126,277
Last modified:February 9, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i19B97F1B51F22B69
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GU236826 Genomic DNA Translation: ADA72264.1
FLMC02000007 Genomic DNA Translation: SCV61963.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
SCV61963; SCV61963; ANAPH2_00140

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU236826 Genomic DNA Translation: ADA72264.1
FLMC02000007 Genomic DNA Translation: SCV61963.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiSCV61963; SCV61963; ANAPH2_00140

Family and domain databases

Gene3Di1.25.40.20, 4 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 15 hits
SUPFAMiSSF48403 SSF48403, 2 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD2KNN0_ANAPH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D2KNN0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: July 31, 2019
This is version 28 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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