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Protein

Serine/threonine-protein kinase receptor

Gene

PANDA_013074

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, ReceptorUniRule annotationSAAS annotation, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotation, ManganeseUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase receptorUniRule annotation (EC:2.7.11.30UniRule annotation)
Gene namesi
ORF Names:PANDA_013074Imported
OrganismiAiluropoda melanoleuca (Giant panda)Imported
Taxonomic identifieri9646 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei115 – 137HelicalUniRule annotationAdd BLAST23

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini169 – 198GSInterPro annotationAdd BLAST30
Domaini199 – 493Protein kinaseInterPro annotationAdd BLAST295

Sequence similaritiesi

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2052 Eukaryota
ENOG410XQT0 LUCA
HOGENOMiHOG000230587

Family and domain databases

InterProiView protein in InterPro
IPR000472 Activin_recp
IPR003605 GS_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
IPR000333 TGFB_receptor
PANTHERiPTHR23255 PTHR23255, 1 hit
PfamiView protein in Pfam
PF01064 Activin_recp, 1 hit
PF00069 Pkinase, 1 hit
PF08515 TGF_beta_GS, 1 hit
PRINTSiPR00653 ACTIVIN2R
SMARTiView protein in SMART
SM00467 GS, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51256 GS, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Fragment.

D2HN36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VVIFFPPSSC SFADEKPKVN PKLYMCVCEG LSCGNEDHCE GQQCFSSLSI
60 70 80 90 100
NDGFHVYQKG CFQVYEQGKM TCKTPPSPGQ AVECCQGDWC NRNITAQLPT
110 120 130 140 150
KGKSFPGTQN FHLEVGLIIL SVVFAVCLLA CLLGVALRKF KRRNQERLNP
160 170 180 190 200
RDVEYGTIEG LITTNVGDST LADLLDHSCT SGSGSGLPFL VQRTVARQIT
210 220 230 240 250
LLECVGKGRY GEVWRGSWQG ENVAVKIFSS RDEKSWFRET ELYNTVMLRH
260 270 280 290 300
ENILGFIASD MTSRHSSTQL WLITHYHEMG SLYDYLQLTT LDTVSCLRIV
310 320 330 340 350
LSIASGLAHL HIEIFGTQGK PAIAHRDLKS KNILVKKNGQ CCIADLGLAV
360 370 380 390 400
MHSQSTNQLD VGNNPRVGTK RYMAPEVLDE TIQVDCFDSY KRVDIWAFGL
410 420 430 440 450
VLWEVARRMV SNGIVEDYKP PFYDVVPNDP SFEDMRKVVC VDQQRPNIPN
460 470 480 490 500
RWFSDPTLTS LAKLMKECWY QNPSARLTAL RIKKTLTKID NSLDKLKTDC
Length:500
Mass (Da):56,197
Last modified:February 9, 2010 - v1
Checksum:i03864C0358919D53
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei500Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL193071 Genomic DNA Translation: EFB17501.1

Similar proteinsi

Entry informationi

Entry nameiD2HN36_AILME
AccessioniPrimary (citable) accession number: D2HN36
Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: June 20, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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