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Entry version 63 (02 Jun 2021)
Sequence version 1 (09 Feb 2010)
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Protein
Submitted name:

Uncharacterized protein

Gene

PANDA_011012

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase, PeroxidaseARBA annotation

Protein family/group databases

PeroxiBase, a peroxidase database

More...
PeroxiBasei
7610, AImePxd01

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PANDA_011012Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAiluropoda melanoleuca (Giant panda)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9646 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

SecretedARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini59 – 145Ig-likeInterPro annotationAdd BLAST87
Domaini155 – 241Ig-likeInterPro annotationAdd BLAST87
Domaini246 – 333Ig-likeInterPro annotationAdd BLAST88
Domaini334 – 425Ig-likeInterPro annotationAdd BLAST92
Domaini1226 – 1284VWFCInterPro annotationAdd BLAST59

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1158 – 1195DisorderedSequence analysisAdd BLAST38

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1202 – 1222Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Leucine-rich repeatARBA annotation, SignalARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006087_0_1_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
GTNDFKE

Family and domain databases

Conserved Domains Database

More...
CDDi
cd09826, peroxidasin_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.640.10, 1 hit
2.60.40.10, 4 hits
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000483, Cys-rich_flank_reg_C
IPR019791, Haem_peroxidase_animal
IPR010255, Haem_peroxidase_sf
IPR037120, Haem_peroxidase_sf_animal
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR032675, LRR_dom_sf
IPR034824, Peroxidasin_peroxidase
IPR034828, Peroxidasin_vert
IPR001007, VWF_dom

The PANTHER Classification System

More...
PANTHERi
PTHR11475:SF75, PTHR11475:SF75, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03098, An_peroxidase, 1 hit
PF07679, I-set, 4 hits
PF00093, VWC, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00457, ANPEROXIDASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00409, IG, 4 hits
SM00408, IGc2, 4 hits
SM00082, LRRCT, 1 hit
SM00214, VWC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48113, SSF48113, 1 hit
SSF48726, SSF48726, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835, IG_LIKE, 4 hits
PS50292, PEROXIDASE_3, 1 hit
PS01208, VWFC_1, 1 hit
PS50184, VWFC_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

D2HIH9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
RLDSNALHCD CEILWLADLL KTYAQSGNAQ AAATCEYPRH IQGRSVATIS
60 70 80 90 100
PEELDCERPR ITSEPQDADV TLGNTVFFTC RAEGNPKPEI IWLRNNNELS
110 120 130 140 150
MKTDSRLNLL DDGTLMIQNT QETDQGIYQC MAKNVAGQVK TQEVTLRYFG
160 170 180 190 200
SPARPAFVIQ PQNTEVLVGE SVTLECSATG HPPPRITWTR GDRTPLPEDP
210 220 230 240 250
RVSITPSGGL YIQNVLQGDS GEYTCFASNS VESIHATALI IVQALPQFTV
260 270 280 290 300
TPADRAVIEG QTVDFQCEAK GYPQPVIAWT KGGSQLSVDR RHLVLSSGTL
310 320 330 340 350
RISAVALHDQ GQYECQAVNI IGSQRAVAHL TVQPRVTPVF ASIPSDMTVE
360 370 380 390 400
VGTNVQLPCS SQGEPEPVIT WNKDGVQVTE SGKFHISPEG FLTIHDVGTA
410 420 430 440 450
DAGRYECVAR NTIGQASVSM VLSVSVPDVS RNGDPFVATS IVEAIATVDR
460 470 480 490 500
AINSTRTHLF DSRPRSPNDL LALFRYPRDP YTVEQARAGE IFERTLQLIQ
510 520 530 540 550
EHVQHGLMVD LNGTSYHYND LVSPQYLSVI ANLSGCTAHR RVNNCSDMCF
560 570 580 590 600
HQKYRTHDGT CNNLQHPMWG ASLTAFERLL KAVYENGFNT PRGIDAGRLY
610 620 630 640 650
HGHALPMPRL VSTSLIGTET ITPDAQFTHM LMQWGQFLDH DLDSTVVALS
660 670 680 690 700
QARFSDGQHC SSVCSSDPPC FSVAVPPNDP RVRSGARCMF FVRSSPVCGS
710 720 730 740 750
GMTSLLMNSV YPREQINQLT SYIDASNVYG STEHEARAIR DLASHRGLLR
760 770 780 790 800
QGIVQRSGKP LLPFAAGPPT ECMRDENESP IPCFLAGDHR ANEQLGLTSM
810 820 830 840 850
HTLWFREHNR VATELLALNP HWDGDTIYHE ARKLVGAQMQ HITYQHWLPK
860 870 880 890 900
VLGEVGMKAL GEYRGYDPGV NAGIVNAFAT AAFRFGHTLI NPVLYRLDEN
910 920 930 940 950
FEPIAQGHVP LHKAFFSPFR IVNEGGIDPL LRGLFGVAGK MRVPSQLLNT
960 970 980 990 1000
ELTERLFSMA HTVALDLAAI NIQRGRDHGI PPYHEYRVYC NLSSAHTFED
1010 1020 1030 1040 1050
LKNEIKNPEI REKLRRLYGS PLNIDLFPAL MVEDLVPGSR LGPTLMCLLS
1060 1070 1080 1090 1100
TQFKRLRDGD RLWYENPGVF SPAQLTQIKQ TSLARILCDN ADNITRVQRD
1110 1120 1130 1140 1150
VFRVVEFPHG YGSCDEVPRV DLRVWQDCCE DCRTRGQFNM FSHHFRGRRS
1160 1170 1180 1190 1200
LGFSYQEDEH AGEVGSGGTP SIGKHRKHPG NATAPSRERP QVPGTSDFKD
1210 1220 1230 1240 1250
FVLEMQKTIT DLREQIKRLE SRLSTGDCTD ADGEPHANGA KWKRDACSVC
1260 1270 1280 1290
ECRDGQVTCF VEACQPANCP APVRARGACC PVCPKDGTGK KP
Length:1,292
Mass (Da):143,045
Last modified:February 9, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i938F2F5D33996706
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei1292Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GL192884 Genomic DNA Translation: EFB14072.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL192884 Genomic DNA Translation: EFB14072.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

PeroxiBasei7610, AImePxd01

Phylogenomic databases

HOGENOMiCLU_006087_0_1_1
OMAiGTNDFKE

Family and domain databases

CDDicd09826, peroxidasin_like, 1 hit
Gene3Di1.10.640.10, 1 hit
2.60.40.10, 4 hits
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR000483, Cys-rich_flank_reg_C
IPR019791, Haem_peroxidase_animal
IPR010255, Haem_peroxidase_sf
IPR037120, Haem_peroxidase_sf_animal
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR032675, LRR_dom_sf
IPR034824, Peroxidasin_peroxidase
IPR034828, Peroxidasin_vert
IPR001007, VWF_dom
PANTHERiPTHR11475:SF75, PTHR11475:SF75, 1 hit
PfamiView protein in Pfam
PF03098, An_peroxidase, 1 hit
PF07679, I-set, 4 hits
PF00093, VWC, 1 hit
PRINTSiPR00457, ANPEROXIDASE
SMARTiView protein in SMART
SM00409, IG, 4 hits
SM00408, IGc2, 4 hits
SM00082, LRRCT, 1 hit
SM00214, VWC, 1 hit
SUPFAMiSSF48113, SSF48113, 1 hit
SSF48726, SSF48726, 4 hits
PROSITEiView protein in PROSITE
PS50835, IG_LIKE, 4 hits
PS50292, PEROXIDASE_3, 1 hit
PS01208, VWFC_1, 1 hit
PS50184, VWFC_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD2HIH9_AILME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D2HIH9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: June 2, 2021
This is version 63 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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