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Entry version 29 (12 Aug 2020)
Sequence version 1 (09 Feb 2010)
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Protein
Submitted name:

Uncharacterized protein

Gene

PANDA_008193

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PANDA_008193Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAiluropoda melanoleuca (Giant panda)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9646 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500303213222 – 1134Sequence analysisAdd BLAST1113

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni71 – 312DisorderedSequence analysisAdd BLAST242
Regioni368 – 703DisorderedSequence analysisAdd BLAST336
Regioni775 – 812DisorderedSequence analysisAdd BLAST38
Regioni877 – 945DisorderedSequence analysisAdd BLAST69
Regioni1013 – 1042DisorderedSequence analysisAdd BLAST30
Regioni1058 – 1088DisorderedSequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi71 – 88Pro-richSequence analysisAdd BLAST18
Compositional biasi89 – 111PolarSequence analysisAdd BLAST23
Compositional biasi112 – 142Pro-richSequence analysisAdd BLAST31
Compositional biasi209 – 228PolyampholyteSequence analysisAdd BLAST20
Compositional biasi231 – 312PolarSequence analysisAdd BLAST82
Compositional biasi439 – 478PolarSequence analysisAdd BLAST40
Compositional biasi488 – 502PolarSequence analysisAdd BLAST15
Compositional biasi558 – 574PolyampholyteSequence analysisAdd BLAST17
Compositional biasi610 – 628PolarSequence analysisAdd BLAST19
Compositional biasi674 – 688PolarSequence analysisAdd BLAST15
Compositional biasi795 – 812PolarSequence analysisAdd BLAST18
Compositional biasi883 – 897PolarSequence analysisAdd BLAST15
Compositional biasi908 – 945PolarSequence analysisAdd BLAST38
Compositional biasi1025 – 1042PolarSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_280412_0_0_1

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015673, Enamelin

The PANTHER Classification System

More...
PANTHERi
PTHR16784, PTHR16784, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15362, Enamelin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

D2HC94-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
VPSGKMKILL VFLGLLGNSV AMPMQMPRMP GFSSKSEEMM RYGQFNFMNS
60 70 80 90 100
PHMAQLGPLY GNGMPPVFPQ YQMPMWPQPP PNMGHPQKPS TPSAPKRQKS
110 120 130 140 150
KTDQVPETQN PNQPQPKKPP PKQPLKQPPP TPAQPEEETQ PPQAFPPFGN
160 170 180 190 200
GLFPPFSNGL YQQPPWQVPH RVPPGYGRPP GSNEEGGNPY FGYFGYQGFG
210 220 230 240 250
GRPPYYSEEM FEQDFEKPKE EDPPKKESPA AEPSGNSTGP ETNSTQSNAP
260 270 280 290 300
NPGGSQGGND TSPTGPNMAQ NGVNSPPTIN VSGQGVPRTQ ITWGPSQPNI
310 320 330 340 350
HENYPNPNNR NFPVGRQWRP TGTIMGHRQN GPFYRNQQFQ RGPRWNSFAL
360 370 380 390 400
ERKQAVRPGN PIYRKAYAST ARGNSPNHAG NLGNFRRKPQ GPNKHPMGTN
410 420 430 440 450
VAPLGPKQGT VVHNEKIQNP AEKPVGPKER IVIPTRDPSG PWRNSQDYGV
460 470 480 490 500
NKSNYKLPHP ESNMLVPNFN SIDQHENSYY PRGDSRRAPN SDGQTQTQNL
510 520 530 540 550
PKGIILEPRR NPYESETNQP ELKHSTYQPV YPEEIPSPAR EHFPAGRNTW
560 570 580 590 600
NHQEISPSFK EDPGRQEEHL PHPSHGSRGG VYYPDSYYHN SYDPRENSPY
610 620 630 640 650
PRSNTWDERD DSPNTIGQPK NSLYPINTPE LKETVPYNEQ DPVDATGDES
660 670 680 690 700
FPGQSRWGME ETSFKEGPTV RHYEGEQYTS NQPKEYLPYS LDNPSKPRED
710 720 730 740 750
FPYGEFYPWN PDEIFPSYNT APTVPPPVES RGYYANNAVG QEESTLFPSW
760 770 780 790 800
NSWDHRIQTQ GQNERQPYFN RNFWNQPTTL HKAPPSPPHQ KENQPYPSNS
810 820 830 840 850
PAGLQKNPTW HEGENLNYGM QITRLNSPDG EHLAFPDLIP PNYPAGQKEA
860 870 880 890 900
HVFHLSQRGP CCAGGSTGHK DNALALQDYT PSFGPASGEN QDTSPLYTED
910 920 930 940 950
SHTKHARHTI SPTSNLPDQR NSSEQRLPGE SQNPSPFRDD VSTLRRNTPC
960 970 980 990 1000
SMKNQLSQRG IMPFPEATSL QSKNMPCLTS DLGGDGNNVL EQIFDDNQFN
1010 1020 1030 1040 1050
ERTVDLTPEQ LVIGTPDEGP QPEGIQSEVQ GNEGERQQQR PSSILQLPCF
1060 1070 1080 1090 1100
GSKIAKYHSS STGTPSSIGR QGPFDEDPIT PTESPNSMSR LATGAEFQSI
1110 1120 1130
NVDPLNADEH TPFDSLQLGT NPQDHVQDCL LLQA
Length:1,134
Mass (Da):126,604
Last modified:February 9, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i72FABE740682BCA0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei1134Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GL192678 Genomic DNA Translation: EFB23252.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL192678 Genomic DNA Translation: EFB23252.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Phylogenomic databases

HOGENOMiCLU_280412_0_0_1

Family and domain databases

InterProiView protein in InterPro
IPR015673, Enamelin
PANTHERiPTHR16784, PTHR16784, 1 hit
PfamiView protein in Pfam
PF15362, Enamelin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD2HC94_AILME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D2HC94
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: August 12, 2020
This is version 29 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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