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Protein
Submitted name:

Uncharacterized protein

Gene

PANDA_006730

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin cappingSAAS annotation, Actin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:PANDA_006730Imported
OrganismiAiluropoda melanoleuca (Giant panda)Imported
Taxonomic identifieri9646 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta subunit.SAAS annotation

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the F-actin-capping protein alpha subunit family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0836 Eukaryota
ENOG410ZAWX LUCA
HOGENOMiHOG000036539
OrthoDBiEOG091G0KST

Family and domain databases

InterProiView protein in InterPro
IPR002189 CapZ_alpha
IPR037282 CapZ_alpha/beta
IPR017865 F-actin_cap_asu_CS
PANTHERiPTHR10653 PTHR10653, 1 hit
PfamiView protein in Pfam
PF01267 F-actin_cap_A, 1 hit
PRINTSiPR00191 FACTINCAPA
SUPFAMiSSF90096 SSF90096, 1 hit
PROSITEiView protein in PROSITE
PS00748 F_ACTIN_CAPPING_A_1, 1 hit
PS00749 F_ACTIN_CAPPING_A_2, 1 hit

Sequencei

Sequence statusi: Fragment.

D2H8X1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
AFAQYNMDQF TPVKIEGYED QVLITEHGDL GNSRFLDPRN KISFKFDHLR
60 70 80 90 100
KEACDPQPED VDGGLKSWRE SCDSALRAYV KDHYSNGFCT VYAKTIDGQQ
110 120 130 140 150
TIIACIESHQ FQPKNFWNGR WRSEWKFTIT PPTAQVVGVL KIQVHYYEDG
160 170 180 190 200
NVQLVSHKDV QDSVTVSNEV QTAKEFIKII EHAENEYQTA ISENYQTMSD
210 220 230
TTFKALRRQL PVTRTKIDWN KILSYKIGKE MQNA
Length:234
Mass (Da):27,096
Last modified:February 9, 2010 - v1
Checksum:i91756D8308EF0399
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei234Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL192586 Genomic DNA Translation: EFB15074.1

Similar proteinsi

Entry informationi

Entry nameiD2H8X1_AILME
AccessioniPrimary (citable) accession number: D2H8X1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: November 22, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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