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Protein

Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Gene

apgM

Organism
Thermotoga naphthophila (strain ATCC BAA-489 / DSM 13996 / JCM 10882 / RKU-10)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.UniRule annotation

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 3 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM)
  4. Enolase (eno)
  5. Pyruvate kinase (Tnap_0838)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationImported
Biological processGlycolysisUniRule annotation
LigandPyruvateImported

Enzyme and pathway databases

BioCyciTNAP590168:G1GGX-1080-MONOMER
UniPathwayiUPA00109; UER00186

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutaseUniRule annotation (EC:5.4.2.12UniRule annotation)
Short name:
BPG-independent PGAMUniRule annotation
Short name:
PhosphoglyceromutaseUniRule annotation
Short name:
aPGAMUniRule annotation
Gene namesi
Name:apgMUniRule annotation
Ordered Locus Names:Tnap_1040Imported
OrganismiThermotoga naphthophila (strain ATCC BAA-489 / DSM 13996 / JCM 10882 / RKU-10)Imported
Taxonomic identifieri590168 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000000940 Componenti: Chromosome

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 390MetalloenzymeInterPro annotationAdd BLAST373

Sequence similaritiesi

Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000004785
KOiK15635
OMAiGDIAFRC

Family and domain databases

CDDicd16011 iPGM_like, 1 hit
Gene3Di3.40.720.10, 2 hits
HAMAPiMF_01402_B ApgM_B, 1 hit
InterProiView protein in InterPro
IPR017849 Alkaline_Pase-like_a/b/a
IPR017850 Alkaline_phosphatase_core_sf
IPR023665 ApgAM_prokaryotes
IPR006124 Metalloenzyme
IPR004456 Pglycerate_mutase_ApgM
PANTHERiPTHR31209 PTHR31209, 1 hit
PfamiView protein in Pfam
PF01676 Metalloenzyme, 1 hit
PF10143 PhosphMutase, 1 hit
PIRSFiPIRSF006392 IPGAM_arch, 1 hit
SUPFAMiSSF53649 SSF53649, 2 hits
TIGRFAMsiTIGR00306 apgM, 1 hit

Sequencei

Sequence statusi: Complete.

D2C841-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDKQEFVSK LVTEEKAKIV LLVMDGLGDI PVNGKTPLQA ANTPNLDNLA
60 70 80 90 100
KESDLGQTIP VLPGITPGSG PGHLSLFGYD PIRYQIGRGI LEALGIGVEV
110 120 130 140 150
GEKDVVARAN FATWDGKVVL DRRAGRPATE ESSKVVQLLS EKIKKIEDVE
160 170 180 190 200
ITFYPGKEHR FVVKFTGEGL GDNVTDADPQ KEGHPMVWAE GLDEPSKKTA
210 220 230 240 250
RITNELIKKI AEVLKDNPKI NFALIRGFSK YPDLPKFPQV YKMKAGAIAT
260 270 280 290 300
YPMYRGLAKL VGMEIIETGQ TVADEIKTLK ERWNDYDFFY VHVKKTDSYG
310 320 330 340 350
EDGKFEEKVK VIEEVDALIP EIVSLNPDVL VITGDHSTPV PLKAHSWHPV
360 370 380 390 400
PLLIWSKYTR RGLSQAFNEF ECARGTLGTI HASDVMTLAL AYAGKLEKFG

A
Length:401
Mass (Da):44,335
Last modified:February 9, 2010 - v1
Checksum:i566E258CD8BE2C22
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001839 Genomic DNA Translation: ADA67127.1
RefSeqiWP_012896315.1, NC_013642.1

Genome annotation databases

EnsemblBacteriaiADA67127; ADA67127; Tnap_1040
KEGGitnp:Tnap_1040

Similar proteinsi

Entry informationi

Entry nameiD2C841_THENR
AccessioniPrimary (citable) accession number: D2C841
Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: March 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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