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Protein

Ribonuclease R

Gene

rnr

Organism
Shigella flexneri serotype X (strain 2002017)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionExonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease RUniRule annotation (EC:3.1.13.1UniRule annotation)
Short name:
RNase RUniRule annotation
Gene namesi
Name:rnrUniRule annotationImported
Ordered Locus Names:SFxv_4723Imported
OrganismiShigella flexneri serotype X (strain 2002017)Imported
Taxonomic identifieri591020 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000001884 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD2AF57
SMRiD2AF57
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini644 – 725S1 motifInterPro annotationAdd BLAST82

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili45 – 65Sequence analysisAdd BLAST21
Coiled coili403 – 423Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the RNR ribonuclease family. RNase R subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000071120
KOiK12573
OMAiDWYEYRS

Family and domain databases

HAMAPiMF_01895 RNase_R, 1 hit
InterProiView protein in InterPro
IPR011129 CSD
IPR012340 NA-bd_OB-fold
IPR013223 RNase_B_OB_dom
IPR022966 RNase_II/R_CS
IPR004476 RNase_II/RNase_R
IPR011805 RNase_R
IPR013668 RNase_R_HTH_12
IPR022967 S1_dom
IPR003029 S1_domain
PfamiView protein in Pfam
PF08461 HTH_12, 1 hit
PF08206 OB_RNB, 2 hits
PF00575 S1, 1 hit
SMARTiView protein in SMART
SM00357 CSP, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 4 hits
TIGRFAMsiTIGR00358 3_prime_RNase, 1 hit
TIGR02063 RNase_R, 1 hit
PROSITEiView protein in PROSITE
PS01175 RIBONUCLEASE_II, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

D2AF57-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQDPFQERE AEKYANPIPS REFILEHLTK REKPASRDEL AVELHIEGEE
60 70 80 90 100
QLEGLRRRLR AMERDGQLVF TRRQCYALPE RLDLVKGTVI GHRDGYGFLR
110 120 130 140 150
VEGRKDDLYL SSEQMKTCIH GDQVLAQPLG ADRKGRREAR IVRVLVPKTS
160 170 180 190 200
QIVGRYFTEA GVGFVVPDDS RLSFDILIPP DQIMGARMGF VVVVELTQRP
210 220 230 240 250
TRRTKAVGKI VEVLGDNMGT GMAVDIALRT HEIPYIWPQA VEQQVAGLKE
260 270 280 290 300
EVPEEAKAGR VDLRDLPLVT IDGEDARDFD DAVYCEKKRG GGWRLWVAIA
310 320 330 340 350
DVSYYVRPPT PLDREARNRG TSVYFPSQVI PMLPEVLSNG LCSLNPQVDR
360 370 380 390 400
LCMVCEMTVS SKGRLTGYKF YEAVMSSHAR LTYTKVWHIL QGDQDLREQY
410 420 430 440 450
APLVKHLEEL HNLYKVLDKA REERGGISFE SEEAKFIFNA ERRIERIEQT
460 470 480 490 500
QRNDAHKLIE ECMILANISA ARFVEKAKEP ALFRIHDKPS TEAITSFRSV
510 520 530 540 550
LAELGLELPG GNKPEPRDYA ELLESVADRP DAEMLQTMLL RSMKQAIYDP
560 570 580 590 600
ENRGHFGLAL QSYAHFTSPI RRYPDLTLHR AIKYLLAKEQ GHQGNTTETG
610 620 630 640 650
GYHYSMEEML QLGQHCSMAE RRADEATRDV ADWLKCDFML DQVGNVFKGV
660 670 680 690 700
ISSVTGFGFF VRLDDLFIDG LVHVSSLDND YYRFDQVGQR LMGESSGQTY
710 720 730 740 750
RLGDRVEVRV EAVNMDERKI DFSLISSERA PRNVGKTARE KAKKGDAGKK
760 770 780 790 800
GGKRCQVGKK VNFEPDSAFR GEKKTKPKAA KKDARKAKKP SAKTQKIAAA
810
TKAKRAAKKK VAE
Length:813
Mass (Da):92,066
Last modified:February 9, 2010 - v1
Checksum:i759B6D1B40C24494
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001383 Genomic DNA Translation: ADA76625.1

Genome annotation databases

EnsemblBacteriaiADA76625; ADA76625; SFxv_4723
KEGGisfe:SFxv_4723
PATRICifig|591020.3.peg.5077

Similar proteinsi

Entry informationi

Entry nameiD2AF57_SHIF2
AccessioniPrimary (citable) accession number: D2AF57
Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: March 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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