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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Edwardsiella tarda (strain EIB202)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotationImported
Ordered Locus Names:ETAE_1426Imported
OrganismiEdwardsiella tarda (strain EIB202)Imported
Taxonomic identifieri498217 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesHafniaceaeEdwardsiella
Proteomesi
  • UP000002634 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi498217.ETAE_1426

Structurei

3D structure databases

ProteinModelPortaliD0ZGZ1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 87Arg_tRNA_synt_NInterPro annotationAdd BLAST87
Domaini461 – 577DALR_1InterPro annotationAdd BLAST117

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

D0ZGZ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNIQAIISDK VTQALVAAGA PADSEALVRP SAKVQFGDYQ ANGIMAAAKK
60 70 80 90 100
MGLPPRQLAE QVVANLALDG IASKVEIAGP GFINIFLDAA WLAAQADAAL
110 120 130 140 150
ADPRLGVARV EPQTIVVDYS APNVAKEMHV GHLRSTIIGD AAVRTLEFLG
160 170 180 190 200
HNVIRANHVG DWGTQFGMLI AYLEKVQGSS KTGDMALADL EAFYREAKKH
210 220 230 240 250
YDEDAAFAER ARGYVVKLQG GDEYCREMWR KLVDITMRQN QRNYDRLNVT
260 270 280 290 300
LTDDDVMGES LYNPMLPGIV ADLKAKGLAT ESEGATVVFL DEFKNKEGEP
310 320 330 340 350
MGVIVQKKDG GYLYTTTDIA CAKYRYETLG ANRILYYIDS RQHQHLMQAW
360 370 380 390 400
AIVRKAGYVP DSVSLEHHMF GMMLGKDGKP FKTRAGGTIK LADLLDEAIE
410 420 430 440 450
RAAKLIAAKN PELSGDELKA LVEVVGIGAV KYADLSKNRT TDYIFDWDNM
460 470 480 490 500
LAFEGNTAPY MQYAYTRVAS IFKRAGIDEN ALQGAITLTE DREKALATRL
510 520 530 540 550
MQFEETILSV AREGTPHVMC AYLYEVAGLF SSFYEACPIL NADEESVCAS
560 570
RLKLAALTAR TLKTGLDTLG IKTVERM
Length:577
Mass (Da):63,297
Last modified:January 19, 2010 - v1
Checksum:iED745E2AFB8AEF70
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001135 Genomic DNA Translation: ACY84267.1
RefSeqiWP_012848279.1, NC_013508.1

Genome annotation databases

EnsemblBacteriaiACY84267; ACY84267; ETAE_1426
KEGGietr:ETAE_1426

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001135 Genomic DNA Translation: ACY84267.1
RefSeqiWP_012848279.1, NC_013508.1

3D structure databases

ProteinModelPortaliD0ZGZ1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi498217.ETAE_1426

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACY84267; ACY84267; ETAE_1426
KEGGietr:ETAE_1426

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD0ZGZ1_EDWTE
AccessioniPrimary (citable) accession number: D0ZGZ1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: March 28, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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