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Entry version 56 (12 Aug 2020)
Sequence version 1 (19 Jan 2010)
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Protein

Dipeptide and tripeptide permease A

Gene

dtpA

Organism
Edwardsiella tarda (strain EIB202)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Proton-dependent permease that transports di- and tripeptides.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processPeptide transport, Protein transport, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ETAR498217:G1GCM-1657-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dipeptide and tripeptide permease AUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dtpAUniRule annotation
Ordered Locus Names:ETAE_1692
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEdwardsiella tarda (strain EIB202)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri498217 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesHafniaceaeEdwardsiella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002634 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 34CytoplasmicUniRule annotationAdd BLAST34
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei35 – 55HelicalUniRule annotationAdd BLAST21
Topological domaini56 – 59PeriplasmicUniRule annotation4
Transmembranei60 – 80HelicalUniRule annotationAdd BLAST21
Topological domaini81 – 89CytoplasmicUniRule annotation9
Transmembranei90 – 110HelicalUniRule annotationAdd BLAST21
Topological domaini111PeriplasmicUniRule annotation1
Transmembranei112 – 132HelicalUniRule annotationAdd BLAST21
Topological domaini133 – 153CytoplasmicUniRule annotationAdd BLAST21
Transmembranei154 – 174HelicalUniRule annotationAdd BLAST21
Topological domaini175 – 176PeriplasmicUniRule annotation2
Transmembranei177 – 197HelicalUniRule annotationAdd BLAST21
Topological domaini198 – 217CytoplasmicUniRule annotationAdd BLAST20
Transmembranei218 – 238HelicalUniRule annotationAdd BLAST21
Topological domaini239 – 246PeriplasmicUniRule annotation8
Transmembranei247 – 267HelicalUniRule annotationAdd BLAST21
Topological domaini268 – 274CytoplasmicUniRule annotation7
Transmembranei275 – 295HelicalUniRule annotationAdd BLAST21
Topological domaini296 – 320PeriplasmicUniRule annotationAdd BLAST25
Transmembranei321 – 341HelicalUniRule annotationAdd BLAST21
Topological domaini342 – 352CytoplasmicUniRule annotationAdd BLAST11
Transmembranei353 – 373HelicalUniRule annotationAdd BLAST21
Topological domaini374 – 383PeriplasmicUniRule annotation10
Transmembranei384 – 404HelicalUniRule annotationAdd BLAST21
Topological domaini405 – 414CytoplasmicUniRule annotation10
Transmembranei415 – 435HelicalUniRule annotationAdd BLAST21
Topological domaini436 – 460PeriplasmicUniRule annotationAdd BLAST25
Transmembranei461 – 481HelicalUniRule annotationAdd BLAST21
Topological domaini482 – 490CytoplasmicUniRule annotation9

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003951751 – 490Dipeptide and tripeptide permease AAdd BLAST490

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
D0Z7W2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004790_0_0_6

KEGG Orthology (KO)

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KOi
K03305

Identification of Orthologs from Complete Genome Data

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OMAi
QMMGVWF

Database of Orthologous Groups

More...
OrthoDBi
470322at2

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_01878, PTR2_DtpA_subfam, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023517, AA/pep_transptr_DtpA
IPR005279, Dipep/tripep_permease
IPR020846, MFS_dom
IPR036259, MFS_trans_sf
IPR000109, POT_fam
IPR018456, PTR2_symporter_CS

The PANTHER Classification System

More...
PANTHERi
PTHR11654, PTHR11654, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00854, PTR2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473, SSF103473, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00924, yjdL_sub1_fam, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850, MFS, 1 hit
PS01022, PTR2_1, 1 hit
PS01023, PTR2_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D0Z7W2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNANNNQPE NVSLNAFKQP RAFYLIFSIE LWERFGYYGL QGIMAVYLVK
60 70 80 90 100
MLGMTEADSI TLFSSFSALV YGFVAIGGWL GDKVLGAKRV IMLGALVLAI
110 120 130 140 150
GYAFVAYSGH DLSLVYVGMA TIAVGNGLFK ANPSSLLSTC YEKNDPRLDG
160 170 180 190 200
AFTMYYMSVN IGSFFSMLAT PWLAARFGWS VAFSLSVVGM LITLVNFMMC
210 220 230 240 250
RRWVKDQGSK PDFAPLQVGK LMMTLVGVVI LVAISTWLLH NQTIARWALA
260 270 280 290 300
IISAGIILIF AKETFALQGG ARRKMIVAFL LMLEAVVFFV LYSQMPTSLN
310 320 330 340 350
FFAIHNVEHS IFGIAFEPEQ YQALNPFWIM VASPILAAIY NKMGDRLPMP
360 370 380 390 400
HKFAIGMVLC SGAFLVLPWG ASFANEAGIV SVNWLILSYA LQSIGELMIS
410 420 430 440 450
GLGLAMVAQL VPQRLMGFIM GSWFLTTAAA ALIAGKVAAL TAVPGGEVAD
460 470 480 490
PHASLAIYSH VFMQIGLATA VIAVLMLLTA PKLNRMTLGD
Length:490
Mass (Da):53,247
Last modified:January 19, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7887A6B47DDEFFF3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP001135 Genomic DNA Translation: ACY84531.1

NCBI Reference Sequences

More...
RefSeqi
WP_012848534.1, NC_013508.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACY84531; ACY84531; ETAE_1692

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51931359

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
etr:ETAE_1692

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001135 Genomic DNA Translation: ACY84531.1
RefSeqiWP_012848534.1, NC_013508.1

3D structure databases

SMRiD0Z7W2
ModBaseiSearch...

Genome annotation databases

EnsemblBacteriaiACY84531; ACY84531; ETAE_1692
GeneIDi51931359
KEGGietr:ETAE_1692

Phylogenomic databases

HOGENOMiCLU_004790_0_0_6
KOiK03305
OMAiQMMGVWF
OrthoDBi470322at2

Enzyme and pathway databases

BioCyciETAR498217:G1GCM-1657-MONOMER

Family and domain databases

HAMAPiMF_01878, PTR2_DtpA_subfam, 1 hit
InterProiView protein in InterPro
IPR023517, AA/pep_transptr_DtpA
IPR005279, Dipep/tripep_permease
IPR020846, MFS_dom
IPR036259, MFS_trans_sf
IPR000109, POT_fam
IPR018456, PTR2_symporter_CS
PANTHERiPTHR11654, PTHR11654, 1 hit
PfamiView protein in Pfam
PF00854, PTR2, 1 hit
SUPFAMiSSF103473, SSF103473, 1 hit
TIGRFAMsiTIGR00924, yjdL_sub1_fam, 1 hit
PROSITEiView protein in PROSITE
PS50850, MFS, 1 hit
PS01022, PTR2_1, 1 hit
PS01023, PTR2_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDTPA_EDWTE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D0Z7W2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: January 19, 2010
Last modified: August 12, 2020
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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