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Entry version 77 (08 May 2019)
Sequence version 2 (11 Nov 2015)
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Protein
Submitted name:

FiLamiN (Actin binding protein) homolog

Gene

fln-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FiLamiN (Actin binding protein) homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fln-2Imported
ORF Names:C23F12.1Imported, CELE_C23F12.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
C23F12.1c ; CE50512 ; WBGene00016006 ; fln-2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
D0VWL7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00016006 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
D0VWL7 baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
D0VWL7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati16 – 107FilaminPROSITE-ProRule annotationAdd BLAST92
Repeati129 – 211FilaminPROSITE-ProRule annotationAdd BLAST83
Repeati229 – 298FilaminPROSITE-ProRule annotationAdd BLAST70
Repeati999 – 1083FilaminPROSITE-ProRule annotationAdd BLAST85
Repeati1081 – 1176FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1255 – 1329FilaminPROSITE-ProRule annotationAdd BLAST75
Repeati1339 – 1416FilaminPROSITE-ProRule annotationAdd BLAST78
Repeati1414 – 1509FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1523 – 1598FilaminPROSITE-ProRule annotationAdd BLAST76
Repeati1661 – 1743FilaminPROSITE-ProRule annotationAdd BLAST83
Repeati1754 – 1826FilaminPROSITE-ProRule annotationAdd BLAST73
Repeati1831 – 1917FilaminPROSITE-ProRule annotationAdd BLAST87
Repeati1927 – 2006FilaminPROSITE-ProRule annotationAdd BLAST80
Repeati2004 – 2098FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2096 – 2189FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati2187 – 2281FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2279 – 2374FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati2415 – 2509FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2511 – 2604FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati2605 – 2701FilaminPROSITE-ProRule annotationAdd BLAST97

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1201 – 1241Sequence analysisAdd BLAST41

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0518 Eukaryota
COG5069 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000175003

Database of Orthologous Groups

More...
OrthoDBi
35998at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 20 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00630 Filamin, 9 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00557 IG_FLMN, 19 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81296 SSF81296, 20 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50194 FILAMIN_REPEAT, 20 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All

D0VWL7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLADQRVPDA PFACNVGAPD LVHVRNMPRR IQPSKLHTDH SFEIDASAAG
60 70 80 90 100
SGNLEIMING GRVPCRVREL GSRQYMAIFT PTQSMTHTIE MRFNGEHVSG
110 120 130 140 150
SPWKLPVEDR GERRQEMERT MSYYSELSGP GLVRAPVNRT AQFDITGEGL
160 170 180 190 200
ELSDIQAKIS GPDNREYPIR IIPRSSGKYT AEYEIEQVGE HHLTVWIAGR
210 220 230 240 250
KVDGSPLSVA GYATEKVRLE PLGGGVPKQP VQFYVDAVEA GKGQLEISVN
260 270 280 290 300
QGKVPNNVQM QGAGRCLVTF IPQHAGTYVI DVTFNGEQVH GCPIKVEILP
310 320 330 340 350
KQVGQQIHAN LTPTAVSTAI SAGGTSLISG AFRETARSPL SARSPTSPTL
360 370 380 390 400
LQHARQRSEE TMLRSPQLLR ESRKADKPWQ SSYAPSSSRN AFSQSPHRDW
410 420 430 440 450
SASTVYDRVY NSNSDVERTL SPSDPSRNRN IRETTTVIHR TPSPTGLRST
460 470 480 490 500
QITETITRTT HRSPSPPRGV SNTSFGSVRT QEFAERIARS PSPTGYEREF
510 520 530 540 550
VEKRTTYRSP SPARTSSVAH SHISEVPLSP IQGMDTPFDH HERVKKVERM
560 570 580 590 600
DPLADEEERE QRRNQLERDS KNTLGYTVAQ YGDGEKRYFG DTLEKKDRPP
610 620 630 640 650
SAGYYSSVQQ RSTSPEYSTV YERYDRKSEK PDLPPRVEGH VSASYKGYEP
660 670 680 690 700
VYSEVTTTRT TTTTEYENID KKPNVPKKRA TTPEGHVEPV NDNEEKDRQA
710 720 730 740 750
FLRTQSEKVF EPVDAPLRRS DEKESIYDLP PQERLHKYPE EPTIALGEKA
760 770 780 790 800
NTSAIAAYTK GRQDDIDEVS RNASFPSAPT INYNERSDEV SNYNRTKEDH
810 820 830 840 850
YGVVGEYPTA PKIAYSDSKE AVIREHYAQA KEDPYATVGE CPPAPEISLR
860 870 880 890 900
SDKLNETKNE YRRTTDSDQQ DGKAGPPPPV IEISKAEQAR RTEEYLRVKS
910 920 930 940 950
EDDKILAKHG FTRKPEPSIE IQEPVTEQIR DDVVETAIAP EVPLRPVEEL
960 970 980 990 1000
PHSPAPSSRS TPATTPKLSA KFRKDGKEGK PFDFGKSKFV CKHDVIKRGK
1010 1020 1030 1040 1050
EVEVKLEGIK LGKEDQLRVV VLPPANKAIP GANGGPPTEV DTKVKKSSSK
1060 1070 1080 1090 1100
YEISFKPTEV GTHKVFAYVN DMQHPLSPFA VRVYDASEII VGEIPNQSNL
1110 1120 1130 1140 1150
NDTVEFTVDA GRAGFGNLEM AIKDADGVII PSHVAQLESG SAKFLVTFTP
1160 1170 1180 1190 1200
ATKGPHTVNI TFNKEVLKNS PFEVNIVDAP LPAPVVLEPA SGASAVASPS
1210 1220 1230 1240 1250
LSKKELKEQE KEKKREEKER AKREKEERAT LKKEKKSKSH RFPAKTTVSK
1260 1270 1280 1290 1300
IPSLSRVGQP SSLVVEVSGH DQLEIRVLDS KKSEIGTDIV EIEPGHMQIN
1310 1320 1330 1340 1350
FTPAQVGDHE IDVRYGGVPV TGSPFTCRAY DPAKIKVGAI PKGLLDKPVY
1360 1370 1380 1390 1400
FTVDASEAGV GNLEVAVCEG RVPSMAHALG HHKYDISFVP KEDVDHTITV
1410 1420 1430 1440 1450
RFNNEPVPGS PFLCQLVATA QATATGAGLE RIPVDEETEI QILTDEIDSA
1460 1470 1480 1490 1500
PEARVRDPQG NDLPVNVTRS RENETLHIAT YVPKCVGNHL IDIFLQGEPI
1510 1520 1530 1540 1550
AGSPFTAKAY DARKTVLVPP ANAVVGKPAT FVIDAARSGA GNMEIIVSVD
1560 1570 1580 1590 1600
NRNVPNFVQA EGQARFKVSF TPQDAKDHTI SVKFNGISVP GSPLICSVSS
1610 1620 1630 1640 1650
AGSVPAAVVL PAAAVIGAET AVAARERIKH TPQHSSEQIK QTTTTVLQKT
1660 1670 1680 1690 1700
PEIRETVEKT GLARELNSAQ IGQKKGFTID NINKSSDCNV IITAPDGSMV
1710 1720 1730 1740 1750
PVSIQKSSTS AYAEFTPTIT GEHLVEIYLD HEIIDEFVIK IKDERHILPP
1760 1770 1780 1790 1800
VCLAGQKYSF DVNSDDKNKV RVTIREPSGR MLPVQMEDLP DGGVRVSCRF
1810 1820 1830 1840 1850
KEVGIHSIDV FVDDQPIGER KMQTVIDPLN GAQLVSEPKR EIVGEQTELK
1860 1870 1880 1890 1900
ILIDSGVESQ VEVIIEGPDR EDNEVFVKKV SETLWSAVWT PKVEGEHELS
1910 1920 1930 1940 1950
ILVAGEQIPG SPFPIHVLDP SAVRVIGLKN APVGVEQQFS VDYTNSGASI
1960 1970 1980 1990 2000
ASVEVRHGDQ TIPITVKKMK PGQLLCTFTP FVDGPHQVEV IIDGVPLSDG
2010 2020 2030 2040 2050
PYEVFISHLG TVRASGDALR KAQRARTARF EVINVEQNRG ELDVMVSDPK
2060 2070 2080 2090 2100
GGPLPVRCYK QQDDSYWVEF TPEHLGTHTI EVTFGDVPVP GSPFKTEVID
2110 2120 2130 2140 2150
PKNVEIRGLS DQVLLRHATT INVDRRNAGN GELQVEITDP TGSPLRTEML
2160 2170 2180 2190 2200
KSPGGEDRIT FLPNQTGPHK INVKVAGFQI PGYPQTILVS EQEKPAVYGA
2210 2220 2230 2240 2250
AVDQSIKIGE PASLIFDPKK TNGGLKIHAT GPDGQKVHHN VMRRPNGTSE
2260 2270 2280 2290 2300
VVFYPEETGT YNVSIDFNNR PITGSPFTVN VVDPTKVIVN DLDMDRDGTL
2310 2320 2330 2340 2350
LLRLGHSNSF DVDATAAGPG KLRAEVRDAD SSLIGNGPVV EDMGQGKYRV
2360 2370 2380 2390 2400
RFNPDQPGKY SIYLYWNELP VESAFPVRAR SSAEDLPTTS RAVREPIPPP
2410 2420 2430 2440 2450
VTTTYHTREK SSGSNADDEI SRIMVRGDGL HRAVLKEHNE FIIDGSDINK
2460 2470 2480 2490 2500
EGRITATLLG SKADIPVRIQ QLGHNVYKAT YTPLTGGTYE LHILWNGKHV
2510 2520 2530 2540 2550
KGSPFAVSAD TSAHLADLID VDASTLKIGI INENIKTLID TRRAGSGQLS
2560 2570 2580 2590 2600
ALCMGPNKPA YCELYDHRDG TYALCVRPAE IGKHTLVIKY DDEHVKGSPF
2610 2620 2630 2640 2650
VVHVSLPPDP SKVRVYGPGV EHGILSLFKS NFVVETRGAG AGQLTVRVRG
2660 2670 2680 2690 2700
PKGAFNVEMQ REKKNERTIH CKYEPKEPGD YQVEVKWHGE HVPGSPFLVM
2710 2720 2730 2740 2750
IVDTEKELSR YLRGEAPSPT PATPFIPPGW VAPPQMYPMQ PGQQRFLPPP
2760 2770
GHFGPMGVPS PYGSVPPPTK HKGRNH
Length:2,776
Mass (Da):305,136
Last modified:November 11, 2015 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDD0E1E58A43A6BDC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D0VWL6D0VWL6_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,672Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0VWL8D0VWL8_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,391Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT74A0A0K3AT74_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,287Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AYI1A0A0K3AYI1_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,656Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AVI4A0A0K3AVI4_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,415Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AWA2A0A0K3AWA2_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,335Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AYH6A0A0K3AYH6_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,654Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASN4A0A0K3ASN4_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,720Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AVH8A0A0K3AVH8_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,479Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASN9A0A0K3ASN9_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,030Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CCD65283.2

NCBI Reference Sequences

More...
RefSeqi
NP_001257074.2, NM_001270145.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C23F12.1c.1; C23F12.1c.1; WBGene00016006
C23F12.1c.2; C23F12.1c.2; WBGene00016006

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181168

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CCD65283.2
RefSeqiNP_001257074.2, NM_001270145.2

3D structure databases

SMRiD0VWL7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiD0VWL7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC23F12.1c.1; C23F12.1c.1; WBGene00016006
C23F12.1c.2; C23F12.1c.2; WBGene00016006
GeneIDi181168

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181168
WormBaseiC23F12.1c ; CE50512 ; WBGene00016006 ; fln-2

Phylogenomic databases

eggNOGiKOG0518 Eukaryota
COG5069 LUCA
HOGENOMiHOG000175003
OrthoDBi35998at2759

Gene expression databases

BgeeiWBGene00016006 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)
ExpressionAtlasiD0VWL7 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 20 hits
InterProiView protein in InterPro
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PfamiView protein in Pfam
PF00630 Filamin, 9 hits
SMARTiView protein in SMART
SM00557 IG_FLMN, 19 hits
SUPFAMiSSF81296 SSF81296, 20 hits
PROSITEiView protein in PROSITE
PS50194 FILAMIN_REPEAT, 20 hits

ProtoNet; Automatic hierarchical classification of proteins

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD0VWL7_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D0VWL7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: November 11, 2015
Last modified: May 8, 2019
This is version 77 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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