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Entry version 81 (10 Apr 2019)
Sequence version 3 (11 Nov 2015)
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Protein
Submitted name:

FiLamiN (Actin binding protein) homolog

Gene

fln-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FiLamiN (Actin binding protein) homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fln-2Imported
ORF Names:C23F12.1Imported, CELE_C23F12.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
C23F12.1a ; CE50487 ; WBGene00016006 ; fln-2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
D0VWL6

PeptideAtlas

More...
PeptideAtlasi
D0VWL6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00016006 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
D0VWL6 baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
D0VWL6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini14 – 118Calponin-homology (CH)InterPro annotationAdd BLAST105
Domaini125 – 228Calponin-homology (CH)InterPro annotationAdd BLAST104
Domaini229 – 332Calponin-homology (CH)InterPro annotationAdd BLAST104
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati635 – 716FilaminPROSITE-ProRule annotationAdd BLAST82
Repeati740 – 820FilaminPROSITE-ProRule annotationAdd BLAST81
Repeati818 – 912FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati912 – 1003FilaminPROSITE-ProRule annotationAdd BLAST92
Repeati1025 – 1107FilaminPROSITE-ProRule annotationAdd BLAST83
Repeati1125 – 1194FilaminPROSITE-ProRule annotationAdd BLAST70
Repeati1895 – 1979FilaminPROSITE-ProRule annotationAdd BLAST85
Repeati1977 – 2072FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati2151 – 2225FilaminPROSITE-ProRule annotationAdd BLAST75
Repeati2235 – 2312FilaminPROSITE-ProRule annotationAdd BLAST78
Repeati2310 – 2405FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati2419 – 2494FilaminPROSITE-ProRule annotationAdd BLAST76
Repeati2557 – 2639FilaminPROSITE-ProRule annotationAdd BLAST83
Repeati2650 – 2722FilaminPROSITE-ProRule annotationAdd BLAST73
Repeati2727 – 2813FilaminPROSITE-ProRule annotationAdd BLAST87
Repeati2823 – 2902FilaminPROSITE-ProRule annotationAdd BLAST80
Repeati2900 – 2994FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2992 – 3085FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati3083 – 3177FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati3175 – 3270FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati3311 – 3405FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati3407 – 3500FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati3501 – 3597FilaminPROSITE-ProRule annotationAdd BLAST97

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2097 – 2137Sequence analysisAdd BLAST41

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0518 Eukaryota
COG5069 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000175003

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
D0VWL6

KEGG Orthology (KO)

More...
KOi
K04437

Identification of Orthologs from Complete Genome Data

More...
OMAi
CHRPGTI

Database of Orthologous Groups

More...
OrthoDBi
35998at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014 CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 3 hits
2.60.40.10, 23 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307 CH, 3 hits
PF00630 Filamin, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033 CH, 3 hits
SM00557 IG_FLMN, 22 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576 SSF47576, 2 hits
SSF81296 SSF81296, 23 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50021 CH, 3 hits
PS50194 FILAMIN_REPEAT, 23 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All

D0VWL6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKQGEEARQ KWIDIQLHTF TNWINEQLQG NVIRDLTQDL SDGVNLIKLV
60 70 80 90 100
EILQGRRYYG KVYDQDPTEI QKLMNVQMAL DALREDGVKT VNIGSHDIVD
110 120 130 140 150
GNEKLILGLI WCLVQRYQIA CKTKIPPKKL VMAWIQSALP ELKLTNFRTN
160 170 180 190 200
WNDGIALSAL LEYCQPGLCP EWRNLDPSEA RENCHRALLL AERYLEVPPI
210 220 230 240 250
ISSDHLSSPH LDELSCLTYL SYFITKGAPG YRATLKKVSM LLPDCNVDDL
260 270 280 290 300
EHSWSDGFLL AHLVEICGGR VPELERMRFD NLNDFVENVA IVLDAAADIG
310 320 330 340 350
VGSLIGADDI AEPQGEHLGT MALVAALCSV SLEQQVKYTD CYVNQQVNLD
360 370 380 390 400
LAFTEGNEVR IEELDVQVVG GNGQLYSNEA IKLRKSRTVQ GANLSLMPVE
410 420 430 440 450
PGFLQNRTSF TLDFKLLFPK TKALPMSILS SRIENSGYES IREKMQSRFY
460 470 480 490 500
HTVRIYCQGS ELPASPISLQ VHTQEETRSS SRAASRAHPE NRNPPASTSK
510 520 530 540 550
YIERTIVSPV SDSRESGKIA QFSTETEVDI SHKSFAQRRL HIIKQLEAQH
560 570 580 590 600
VNHIAQTKSH HQQHTQQQQH HQTVPTQSSS IVQVVQPIPP PPPTLAQSSS
610 620 630 640 650
NIPPPPPIPA VLEASAYREM PLTRSPDVGL VSFSGLTEPC SVGSIVEVVI
660 670 680 690 700
NAHGDAVSGS VYVEAVSPSG NVHRCTVRHQ DNSYMATFTP QEVGLWRIGI
710 720 730 740 750
LYDGEHIRGS PFACQVYHLD RRSLITRRQV FDSGLVNVYG LDVGLVGQEL
760 770 780 790 800
NFSVNASQAG HGNLSVTVFR HGREIPLSIE EQGSSKVHQV SFTPDGAGQY
810 820 830 840 850
KIHVLFNRME IKGSPFILDI ADASSVSVYG ENLRSASVGK TASFMVHAIG
860 870 880 890 900
AEAKDISAHV TVPSGGKFPA KVVTLDDVTF QIEWTPKEPG EHSVDVMLAD
910 920 930 940 950
QRVPDAPFAC NVGAPDLVHV RNMPRRIQPS KLHTDHSFEI DASAAGSGNL
960 970 980 990 1000
EIMINGGRVP CRVRELGSRQ YMAIFTPTQS MTHTIEMRFN GEHVSGSPWK
1010 1020 1030 1040 1050
LPVEDRGERR QEMERTMSYY SELSGPGLVR APVNRTAQFD ITGEGLELSD
1060 1070 1080 1090 1100
IQAKISGPDN REYPIRIIPR SSGKYTAEYE IEQVGEHHLT VWIAGRKVDG
1110 1120 1130 1140 1150
SPLSVAGYAT EKVRLEPLGG GVPKQPVQFY VDAVEAGKGQ LEISVNQGKV
1160 1170 1180 1190 1200
PNNVQMQGAG RCLVTFIPQH AGTYVIDVTF NGEQVHGCPI KVEILPKQVG
1210 1220 1230 1240 1250
QQIHANLTPT AVSTAISAGG TSLISGAFRE TARSPLSARS PTSPTLLQHA
1260 1270 1280 1290 1300
RQRSEETMLR SPQLLRESRK ADKPWQSSYA PSSSRNAFSQ SPHRDWSAST
1310 1320 1330 1340 1350
VYDRVYNSNS DVERTLSPSD PSRNRNIRET TTVIHRTPSP TGLRSTQITE
1360 1370 1380 1390 1400
TITRTTHRSP SPPRGVSNTS FGSVRTQEFA ERIARSPSPT GYEREFVEKR
1410 1420 1430 1440 1450
TTYRSPSPAR TSSVAHSHIS EVPLSPIQGM DTPFDHHERV KKVERMDPLA
1460 1470 1480 1490 1500
DEEEREQRRN QLERDSKNTL GYTVAQYGDG EKRYFGDTLE KKDRPPSAGY
1510 1520 1530 1540 1550
YSSVQQRSTS PEYSTVYERY DRKSEKPDLP PRVEGHVSAS YKGYEPVYSE
1560 1570 1580 1590 1600
VTTTRTTTTT EYENIDKKPN VPKKRATTPE GHVEPVNDNE EKDRQAFLRT
1610 1620 1630 1640 1650
QSEKVFEPVD APLRRSDEKE SIYDLPPQER LHKYPEEPTI ALGEKANTSA
1660 1670 1680 1690 1700
IAAYTKGRQD DIDEVSRNAS FPSAPTINYN ERSDEVSNYN RTKEDHYGVV
1710 1720 1730 1740 1750
GEYPTAPKIA YSDSKEAVIR EHYAQAKEDP YATVGECPPA PEISLRSDKL
1760 1770 1780 1790 1800
NETKNEYRRT TDSDQQDGKA GPPPPVIEIS KAEQARRTEE YLRVKSEDDK
1810 1820 1830 1840 1850
ILAKHGFTRK PEPSIEIQEP VTEQIRDDVV ETAIAPEVPL RPVEELPHSP
1860 1870 1880 1890 1900
APSSRSTPAT TPKLSAKFRK DGKEGKPFDF GKSKFVCKHD VIKRGKEVEV
1910 1920 1930 1940 1950
KLEGIKLGKE DQLRVVVLPP ANKAIPGANG GPPTEVDTKV KKSSSKYEIS
1960 1970 1980 1990 2000
FKPTEVGTHK VFAYVNDMQH PLSPFAVRVY DASEIIVGEI PNQSNLNDTV
2010 2020 2030 2040 2050
EFTVDAGRAG FGNLEMAIKD ADGVIIPSHV AQLESGSAKF LVTFTPATKG
2060 2070 2080 2090 2100
PHTVNITFNK EVLKNSPFEV NIVDAPLPAP VVLEPASGAS AVASPSLSKK
2110 2120 2130 2140 2150
ELKEQEKEKK REEKERAKRE KEERATLKKE KKSKSHRFPA KTTVSKIPSL
2160 2170 2180 2190 2200
SRVGQPSSLV VEVSGHDQLE IRVLDSKKSE IGTDIVEIEP GHMQINFTPA
2210 2220 2230 2240 2250
QVGDHEIDVR YGGVPVTGSP FTCRAYDPAK IKVGAIPKGL LDKPVYFTVD
2260 2270 2280 2290 2300
ASEAGVGNLE VAVCEGRVPS MAHALGHHKY DISFVPKEDV DHTITVRFNN
2310 2320 2330 2340 2350
EPVPGSPFLC QLVATAQATA TGAGLERIPV DEETEIQILT DEIDSAPEAR
2360 2370 2380 2390 2400
VRDPQGNDLP VNVTRSRENE TLHIATYVPK CVGNHLIDIF LQGEPIAGSP
2410 2420 2430 2440 2450
FTAKAYDARK TVLVPPANAV VGKPATFVID AARSGAGNME IIVSVDNRNV
2460 2470 2480 2490 2500
PNFVQAEGQA RFKVSFTPQD AKDHTISVKF NGISVPGSPL ICSVSSAGSV
2510 2520 2530 2540 2550
PAAVVLPAAA VIGAETAVAA RERIKHTPQH SSEQIKQTTT TVLQKTPEIR
2560 2570 2580 2590 2600
ETVEKTGLAR ELNSAQIGQK KGFTIDNINK SSDCNVIITA PDGSMVPVSI
2610 2620 2630 2640 2650
QKSSTSAYAE FTPTITGEHL VEIYLDHEII DEFVIKIKDE RHILPPVCLA
2660 2670 2680 2690 2700
GQKYSFDVNS DDKNKVRVTI REPSGRMLPV QMEDLPDGGV RVSCRFKEVG
2710 2720 2730 2740 2750
IHSIDVFVDD QPIGERKMQT VIDPLNGAQL VSEPKREIVG EQTELKILID
2760 2770 2780 2790 2800
SGVESQVEVI IEGPDREDNE VFVKKVSETL WSAVWTPKVE GEHELSILVA
2810 2820 2830 2840 2850
GEQIPGSPFP IHVLDPSAVR VIGLKNAPVG VEQQFSVDYT NSGASIASVE
2860 2870 2880 2890 2900
VRHGDQTIPI TVKKMKPGQL LCTFTPFVDG PHQVEVIIDG VPLSDGPYEV
2910 2920 2930 2940 2950
FISHLGTVRA SGDALRKAQR ARTARFEVIN VEQNRGELDV MVSDPKGGPL
2960 2970 2980 2990 3000
PVRCYKQQDD SYWVEFTPEH LGTHTIEVTF GDVPVPGSPF KTEVIDPKNV
3010 3020 3030 3040 3050
EIRGLSDQVL LRHATTINVD RRNAGNGELQ VEITDPTGSP LRTEMLKSPG
3060 3070 3080 3090 3100
GEDRITFLPN QTGPHKINVK VAGFQIPGYP QTILVSEQEK PAVYGAAVDQ
3110 3120 3130 3140 3150
SIKIGEPASL IFDPKKTNGG LKIHATGPDG QKVHHNVMRR PNGTSEVVFY
3160 3170 3180 3190 3200
PEETGTYNVS IDFNNRPITG SPFTVNVVDP TKVIVNDLDM DRDGTLLLRL
3210 3220 3230 3240 3250
GHSNSFDVDA TAAGPGKLRA EVRDADSSLI GNGPVVEDMG QGKYRVRFNP
3260 3270 3280 3290 3300
DQPGKYSIYL YWNELPVESA FPVRARSSAE DLPTTSRAVR EPIPPPVTTT
3310 3320 3330 3340 3350
YHTREKSSGS NADDEISRIM VRGDGLHRAV LKEHNEFIID GSDINKEGRI
3360 3370 3380 3390 3400
TATLLGSKAD IPVRIQQLGH NVYKATYTPL TGGTYELHIL WNGKHVKGSP
3410 3420 3430 3440 3450
FAVSADTSAH LADLIDVDAS TLKIGIINEN IKTLIDTRRA GSGQLSALCM
3460 3470 3480 3490 3500
GPNKPAYCEL YDHRDGTYAL CVRPAEIGKH TLVIKYDDEH VKGSPFVVHV
3510 3520 3530 3540 3550
SLPPDPSKVR VYGPGVEHGI LSLFKSNFVV ETRGAGAGQL TVRVRGPKGA
3560 3570 3580 3590 3600
FNVEMQREKK NERTIHCKYE PKEPGDYQVE VKWHGEHVPG SPFLVMIVDT
3610 3620 3630 3640 3650
EKELSRYLRG EAPSPTPATP FIPPGWVAPP QMYPMQPGQQ RFLPPPGHFG
3660 3670
PMGVPSPYGS VPPPTKHKGR NH
Length:3,672
Mass (Da):404,283
Last modified:November 11, 2015 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3A04F8C517C4C1D4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D0VWL7D0VWL7_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,776Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0VWL8D0VWL8_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,391Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT74A0A0K3AT74_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,287Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AYI1A0A0K3AYI1_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,656Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT86A0A0K3AT86_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,271Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AVH5A0A0K3AVH5_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,243Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASN4A0A0K3ASN4_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,720Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AVH8A0A0K3AVH8_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,479Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASM8A0A0K3ASM8_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
1,889Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT80A0A0K3AT80_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,864Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
BX284606 Genomic DNA Translation: CCD65284.3

NCBI Reference Sequences

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RefSeqi
NP_509580.6, NM_077179.6

Genome annotation databases

Ensembl metazoan genome annotation project

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EnsemblMetazoai
C23F12.1a; C23F12.1a; WBGene00016006

Database of genes from NCBI RefSeq genomes

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GeneIDi
181168

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C23F12.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CCD65284.3
RefSeqiNP_509580.6, NM_077179.6

3D structure databases

SMRiD0VWL6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiD0VWL6
PeptideAtlasiD0VWL6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC23F12.1a; C23F12.1a; WBGene00016006
GeneIDi181168
KEGGicel:CELE_C23F12.1

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181168
WormBaseiC23F12.1a ; CE50487 ; WBGene00016006 ; fln-2

Phylogenomic databases

eggNOGiKOG0518 Eukaryota
COG5069 LUCA
HOGENOMiHOG000175003
InParanoidiD0VWL6
KOiK04437
OMAiCHRPGTI
OrthoDBi35998at2759

Gene expression databases

BgeeiWBGene00016006 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)
ExpressionAtlasiD0VWL6 baseline and differential

Family and domain databases

CDDicd00014 CH, 2 hits
Gene3Di1.10.418.10, 3 hits
2.60.40.10, 23 hits
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PfamiView protein in Pfam
PF00307 CH, 3 hits
PF00630 Filamin, 10 hits
SMARTiView protein in SMART
SM00033 CH, 3 hits
SM00557 IG_FLMN, 22 hits
SUPFAMiSSF47576 SSF47576, 2 hits
SSF81296 SSF81296, 23 hits
PROSITEiView protein in PROSITE
PS50021 CH, 3 hits
PS50194 FILAMIN_REPEAT, 23 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD0VWL6_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D0VWL6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: November 11, 2015
Last modified: April 10, 2019
This is version 81 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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