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Protein

Superoxide dismutase [Cu-Zn]

Gene

Gbro_0664

Organism
Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciGBRO526226:G1GGH-665-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Gbro_0664Imported
OrganismiGordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis)Imported
Taxonomic identifieri526226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesGordoniaceaeGordonia
Proteomesi
  • UP000001219 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500301016429 – 218Superoxide dismutase [Cu-Zn]Sequence analysisAdd BLAST190

Interactioni

Protein-protein interaction databases

STRINGi526226.Gbro_0664

Structurei

3D structure databases

ProteinModelPortaliD0L2A2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 214Sod_CuInterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105H08 Bacteria
COG2032 LUCA
HOGENOMiHOG000263448
KOiK04565
OMAiHKGDIGN
OrthoDBiPOG091H05EB

Family and domain databases

Gene3Di2.60.40.200, 1 hit
InterProiView protein in InterPro
IPR036423 SOD-like_Cu/Zn_dom_sf
IPR024134 SOD_Cu/Zn_/chaperone
IPR018152 SOD_Cu/Zn_BS
IPR001424 SOD_Cu_Zn_dom
PANTHERiPTHR10003 PTHR10003, 1 hit
PfamiView protein in Pfam
PF00080 Sod_Cu, 1 hit
SUPFAMiSSF49329 SSF49329, 1 hit
PROSITEiView protein in PROSITE
PS00332 SOD_CU_ZN_2, 1 hit

Sequencei

Sequence statusi: Complete.

D0L2A2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTATTHRPTT LRVIAALASA GAIGAVLAGC TPDEPPTDAK GTTPSVISGP
60 70 80 90 100
PLPPGSVQNE DDVPTGQQAK AEIKNPDGEV VGEATFTARN PDGPVTVNVR
110 120 130 140 150
VTGGDIAPGF HGMHIHANGQ CAPKDGEDFG AAGGHLQVGA ANAHPSSGDL
160 170 180 190 200
VSINILNDHT GETVTTTDRV KLSQIVDKSI IIHEKPDNFG NVPNPSEKTL
210
MTGDAGARVA CGVISLEQ
Length:218
Mass (Da):22,141
Last modified:December 15, 2009 - v1
Checksum:i860FF7E7D213070C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001802 Genomic DNA Translation: ACY19989.1
RefSeqiWP_012832576.1, NC_013441.1

Genome annotation databases

EnsemblBacteriaiACY19989; ACY19989; Gbro_0664
KEGGigbr:Gbro_0664

Similar proteinsi

Entry informationi

Entry nameiD0L2A2_GORB4
AccessioniPrimary (citable) accession number: D0L2A2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: February 28, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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