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Entry version 74 (08 May 2019)
Sequence version 1 (15 Dec 2009)
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Protein
Submitted name:

FiLamiN (Actin binding protein) homolog

Gene

fln-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • actin filament organization Source: WormBase
  • uterus morphogenesis Source: WormBase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FiLamiN (Actin binding protein) homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fln-1Imported
ORF Names:CELE_Y66H1B.2Imported, Y66H1B.2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...
WormBasei
Y66H1B.2f ; CE44255 ; WBGene00022048 ; fln-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
D0IMZ7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00022048 Expressed in 5 organ(s), highest expression level in multi-cellular organism

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
D0IMZ7 baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
D0IMZ7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini26 – 132Calponin-homology (CH)InterPro annotationAdd BLAST107
Domaini150 – 253Calponin-homology (CH)InterPro annotationAdd BLAST104
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati252 – 354FilaminPROSITE-ProRule annotationAdd BLAST103
Repeati367 – 442FilaminPROSITE-ProRule annotationAdd BLAST76
Repeati541 – 632FilaminPROSITE-ProRule annotationAdd BLAST92
Repeati636 – 732FilaminPROSITE-ProRule annotationAdd BLAST97
Repeati733 – 828FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati921 – 1017FilaminPROSITE-ProRule annotationAdd BLAST97
Repeati1325 – 1420FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1420 – 1512FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati1509 – 1598FilaminPROSITE-ProRule annotationAdd BLAST90
Repeati1601 – 1693FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati1718 – 1791FilaminPROSITE-ProRule annotationAdd BLAST74
Repeati1794 – 1886FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati1908 – 1982FilaminPROSITE-ProRule annotationAdd BLAST75
Repeati1985 – 2076FilaminPROSITE-ProRule annotationAdd BLAST92
Repeati2110 – 2204FilaminPROSITE-ProRule annotationAdd BLAST95

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0518 Eukaryota
COG5069 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000173830

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000044235

KEGG Orthology (KO)

More...
KOi
K04437

Database of Orthologous Groups

More...
OrthoDBi
35998at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014 CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits
2.60.40.10, 17 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307 CH, 2 hits
PF00630 Filamin, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033 CH, 2 hits
SM00557 IG_FLMN, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576 SSF47576, 1 hit
SSF81296 SSF81296, 16 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50021 CH, 2 hits
PS50194 FILAMIN_REPEAT, 15 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All

D0IMZ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQPKRLDQE EEVVPAIRHD DAEWKIIQQN TFTRWVKNHL QKAGETIESL
60 70 80 90 100
ETDFSDGLKL IALAQVLSHK NVGKFNKKVA FRSQKLENVS LALNFFQNEE
110 120 130 140 150
NIKIINIDST HIVDHNKKLI LGLVWTLILH YSISMGWIQE KREDGDNKEE
160 170 180 190 200
TPKQKLLNWI RNRLPGMPIS NFTSDWNDGV ALGALVNSMA PGALEDWENW
210 220 230 240 250
SPNDALENTE KAMKSAQDLL KVAPLIAPAE MIHPEIDEMS VMTYLSQFPA
260 270 280 290 300
TKPIIMKPKV QATISNLDKI LQVNDPREFD LKLSRDGFKP KVSIRDEDGQ
310 320 330 340 350
DIHLSLKKVE DKENAYKVKF TPTKIGFIHV DVAANDVHTF ETQTIPEASV
360 370 380 390 400
ICQVVPIARL LDYNKTAKVG DDVKFAVVDA IEGPVEAIVV DPTGKEHRMV
410 420 430 440 450
ILDGTSPGEH SFEYKIPCIG LHSVNVFHKK LPLTGSPFPL RGKPKNSFKV
460 470 480 490 500
WGRGIAPEGI RKNDVVGVHV ESLDPEENIA NANISLEVLK PSDGSHLPVS
510 520 530 540 550
VGYNDESQSM DFEYSPKQAP DDLEVLVKVA GEVIESHKIH VAPESSSKIR
560 570 580 590 600
AFGAGLEGGI VNEPCVFDVE MNGESKDLSF AVEGPSKAEI GCQERPDGSA
610 620 630 640 650
ILSYTPTVAG VYKVGVLADG KHIQDSPFVL RVTEPIEGLK PSATRVTGID
660 670 680 690 700
ESKVYNVGEK IPFRVDTRLC GVDLVPKVEI LDPELNPISY GAREITPGLF
710 720 730 740 750
EYTLIPDAPI KHKIDVSVAG VSVPGAPFSV KVKEPTDASK LKIFGPGVDG
760 770 780 790 800
PVYSKEPTRF TIDATQAGPG AVEVALRDDQ GENVDLDVLD NQDGSFTVKY
810 820 830 840 850
TAQRPGAYQL NVVFAGEEIS PIEINVKPNV DVSGIRVEGL ENENLLIGSH
860 870 880 890 900
LRPTINIGKL EPKSKGLQLI DEVNGKRYNV PMKINPDGTY STDTPLMEVG
910 920 930 940 950
EHKLQLLFDE IPVKEAVVEV IKGTDVNKCK AYGPGLEQAV VGEKAVFELD
960 970 980 990 1000
LDGAGEGALS MEMRGPAKAE SRIQDRGNGK CSVEYVAKAP GDYEMAIKFG
1010 1020 1030 1040 1050
KDEQKEHVKG SPFKAVVDYK KDPSQITISG LDQPNYRLNQ PINFVIDTSK
1060 1070 1080 1090 1100
TKDLPVKATV PSDFAQLQPV VSRSPSNPRH HNVRFVPSGK PNVSIPIEII
1110 1120 1130 1140 1150
YDGLKIDEKL VKVLPEVEPQ LIKILHDKKK DSLTTTPITT NASHEGHVPF
1160 1170 1180 1190 1200
DVRDCGNVKK IESRVFGPDG KERLNHVRST EQNGIYDVSF PTDMAGEYCV
1210 1220 1230 1240 1250
VFYINGQEVA ARVPVMAEKI GRKEDVIKEE IVFHPEIAEH SPTVLTYNHP
1260 1270 1280 1290 1300
IDAKKKKAHP AIQVLAAKPD AVRLEHIQEL VDNGHRVADR IVFTATKLGT
1310 1320 1330 1340 1350
NTLDVFYGGE HVDHVEYEAI GKLEYERIQA ERAKVVVEKE DDVDKYEKQY
1360 1370 1380 1390 1400
KFNVRDLGYQ PKDLEAIVMP PTQKKEVAEI IDNLDGTILV KYTPKVHGSH
1410 1420 1430 1440 1450
ELSILQNGAQ LQGTPIKFYV DAYGDGWATV YGPGLQNAVV GEPATFTVCA
1460 1470 1480 1490 1500
KGSQAKELSV SIEGPAKSQI KIHDNKDGTC SAAWVPPVPG EYKVHVKLGG
1510 1520 1530 1540 1550
KAVKDSPFRV LVMGEGQKRS HLSVGSTSEV ALPITQQELK GISASIKSPG
1560 1570 1580 1590 1600
GIEEPCFVRL LDGGRLGVSF TPREAGEHLI TVKRDGKLVP KAPFKIKVDK
1610 1620 1630 1640 1650
TQVGDASKVE VSGSGKAKGI TLQANELLVD TSKAGYGGLS VSVQGPSKAE
1660 1670 1680 1690 1700
LTCKEVKSGL IKVLYTPTEP GVYAIAIKFA DHHVKDSPLT VQCTGKSAGR
1710 1720 1730 1740 1750
VIQTIQKDVE QHGICLPDQE SHLFLKLLNT SPMDITARLM DPKGHTDDIE
1760 1770 1780 1790 1800
MRDLGQQYYQ LKFTPKMEGI HTLSVMYKDA HVNGSPFQFT VGSFSEGGAH
1810 1820 1830 1840 1850
KVRAAGQGVV RGETGTFNAF NIYHREAGVG AVAVTIEGPS KATLEFKDHN
1860 1870 1880 1890 1900
DGNCHVDYKV ATPGEYVVAV KFNDQHIPDS PFKVYIAPAT GEVRKLELAQ
1910 1920 1930 1940 1950
FHGQGIPAGK AFTFTVLTHR AKGHLEAKVV TPNNEVDTID IVPIEDGESY
1960 1970 1980 1990 2000
AMRFVPKETG NHFIHVTLDG APMRESPFRL RVGGKDLCDP TAISASGDGL
2010 2020 2030 2040 2050
VKGTTGQKCE FVINTANAGA GILTVQMDGP SKATLDAYEL EKGYKVRYTP
2060 2070 2080 2090 2100
LAPGSYFASV KYNGIHAPGS PFKIPVEGKE LGGNGYNETS HVKIDAVAKT
2110 2120 2130 2140 2150
SKGTVAVVPE YQGDAAKVTA KGAGLNKFFP GRPAAFQIDT GLAGTNLLMV
2160 2170 2180 2190 2200
GVVTTKGPCE EVVVRHQGSG HYVCSYRIPD RVKGFVFIKY GDKEIPGSPF

AIEP
Length:2,204
Mass (Da):240,574
Last modified:December 15, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEFC73DD1E249EC71
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D0IMZ5D0IMZ5_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
2,255Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9TYW4Q9TYW4_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
1,084Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
U4PBJ9U4PBJ9_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
2,259Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0IMZ8D0IMZ8_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
2,206Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0IMZ6D0IMZ6_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
836Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
U4PBK4U4PBK4_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
2,123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
U4PB58U4PB58_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
2,123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
U4PM01U4PM01_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
2,257Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
U4PR92U4PR92_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
2,257Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
U4PM04U4PM04_CAEEL
FiLamiN (Actin binding protein) hom...
fln-1 CELE_Y66H1B.2, Y66H1B.2
2,121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD69681.1

NCBI Reference Sequences

More...
RefSeqi
NP_001255220.1, NM_001268291.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
Y66H1B.2f; Y66H1B.2f; WBGene00022048

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
176855

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_Y66H1B.2

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD69681.1
RefSeqiNP_001255220.1, NM_001268291.1

3D structure databases

SMRiD0IMZ7
ModBaseiSearch...

Proteomic databases

PeptideAtlasiD0IMZ7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY66H1B.2f; Y66H1B.2f; WBGene00022048
GeneIDi176855
KEGGicel:CELE_Y66H1B.2

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
176855
WormBaseiY66H1B.2f ; CE44255 ; WBGene00022048 ; fln-1

Phylogenomic databases

eggNOGiKOG0518 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00940000173830
HOGENOMiHOG000044235
KOiK04437
OrthoDBi35998at2759

Gene expression databases

BgeeiWBGene00022048 Expressed in 5 organ(s), highest expression level in multi-cellular organism
ExpressionAtlasiD0IMZ7 baseline and differential

Family and domain databases

CDDicd00014 CH, 2 hits
Gene3Di1.10.418.10, 2 hits
2.60.40.10, 17 hits
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PfamiView protein in Pfam
PF00307 CH, 2 hits
PF00630 Filamin, 8 hits
SMARTiView protein in SMART
SM00033 CH, 2 hits
SM00557 IG_FLMN, 15 hits
SUPFAMiSSF47576 SSF47576, 1 hit
SSF81296 SSF81296, 16 hits
PROSITEiView protein in PROSITE
PS50021 CH, 2 hits
PS50194 FILAMIN_REPEAT, 15 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD0IMZ7_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D0IMZ7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: May 8, 2019
This is version 74 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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