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Entry version 50 (05 Jun 2019)
Sequence version 1 (24 Nov 2009)
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Protein

Sodium channel protein PaFPC1

Gene
N/A
Organism
Periplaneta americana (American cockroach) (Blatta americana)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the voltage-dependent sodium ion permeability of excitable membranes.UniRule annotation1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel, Sodium channel, Voltage-gated channel
Biological processIon transport, Sodium transport, Transport
LigandSodium

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.1.10.20 the voltage-gated ion channel (vic) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium channel protein PaFPC11 Publication
Short name:
PaFPC11 Publication
Alternative name(s):
NavPaS1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPeriplaneta americana (American cockroach) (Blatta americana)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6978 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraPolyneopteraDictyopteraBlattodeaBlattoideaBlattidaeBlattinaePeriplaneta

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 140CytoplasmicCombined sources1 PublicationAdd BLAST140
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei141 – 159Helical; Name=S1 of repeat ICombined sources1 PublicationAdd BLAST19
Topological domaini160 – 165ExtracellularCombined sources1 Publication6
Transmembranei166 – 186Helical; Name=S2 of repeat ICombined sources1 PublicationAdd BLAST21
Topological domaini187 – 200CytoplasmicCombined sources1 PublicationAdd BLAST14
Transmembranei201 – 218Helical; Name=S3 of repeat ICombined sources1 PublicationAdd BLAST18
Topological domaini219 – 224ExtracellularCombined sources1 Publication6
Transmembranei225 – 241Helical; Name=S4 of repeat ICombined sources1 PublicationAdd BLAST17
Topological domaini242 – 260CytoplasmicCombined sources1 PublicationAdd BLAST19
Transmembranei261 – 280Helical; Name=S5 of repeat ICombined sources1 PublicationAdd BLAST20
Topological domaini281 – 360ExtracellularCombined sources1 PublicationAdd BLAST80
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a region that is buried within a membrane, but does not cross it.<p><a href='/help/intramem' target='_top'>More...</a></p>Intramembranei361 – 385Pore-formingCombined sources1 PublicationAdd BLAST25
Topological domaini386 – 392ExtracellularCombined sources1 Publication7
Transmembranei393 – 413Helical; Name=S6 of repeat ICombined sources1 PublicationAdd BLAST21
Topological domaini414 – 519CytoplasmicCombined sources1 PublicationAdd BLAST106
Transmembranei520 – 538Helical; Name=S1 of repeat IICombined sources1 PublicationAdd BLAST19
Topological domaini539 – 549ExtracellularCombined sources1 PublicationAdd BLAST11
Transmembranei550 – 569Helical; Name=S2 of repeat IICombined sources1 PublicationAdd BLAST20
Topological domaini570 – 583CytoplasmicCombined sources1 PublicationAdd BLAST14
Transmembranei584 – 603Helical; Name=S3 of repeat IICombined sources1 PublicationAdd BLAST20
Topological domaini604 – 605ExtracellularCombined sources1 Publication2
Transmembranei606 – 623Helical; Name=S4 of repeat IICombined sources1 PublicationAdd BLAST18
Topological domaini624 – 639CytoplasmicCombined sources1 PublicationAdd BLAST16
Transmembranei640 – 658Helical; Name=S5 of repeat IICombined sources1 PublicationAdd BLAST19
Topological domaini659 – 686ExtracellularCombined sources1 PublicationAdd BLAST28
Intramembranei687 – 707Pore-formingCombined sources1 PublicationAdd BLAST21
Topological domaini708 – 719ExtracellularCombined sources1 PublicationAdd BLAST12
Transmembranei720 – 740Helical; Name=S6 of repeat IICombined sources1 PublicationAdd BLAST21
Topological domaini741 – 857CytoplasmicCombined sources1 PublicationAdd BLAST117
Transmembranei858 – 875Helical; Name=S1 of repeat IIICombined sources1 PublicationAdd BLAST18
Topological domaini876 – 888ExtracellularCombined sources1 PublicationAdd BLAST13
Transmembranei889 – 907Helical; Name=S2 of repeat IIICombined sources1 PublicationAdd BLAST19
Topological domaini908 – 921CytoplasmicCombined sources1 PublicationAdd BLAST14
Transmembranei922 – 940Helical; Name=S3 of repeat IIICombined sources1 PublicationAdd BLAST19
Topological domaini941 – 945ExtracellularCombined sources1 Publication5
Transmembranei946 – 964Helical; Name=S4 of repeat IIICombined sources1 PublicationAdd BLAST19
Topological domaini965 – 981CytoplasmicCombined sources1 PublicationAdd BLAST17
Transmembranei982 – 1001Helical; Name=S5 of repeat IIICombined sources1 PublicationAdd BLAST20
Topological domaini1002 – 1047ExtracellularCombined sources1 PublicationAdd BLAST46
Intramembranei1048 – 1069Pore-formingCombined sources1 PublicationAdd BLAST22
Topological domaini1070 – 1086ExtracellularCombined sources1 PublicationAdd BLAST17
Transmembranei1087 – 1108Helical; Name=S6 of repeat IIICombined sources1 PublicationAdd BLAST22
Topological domaini1109 – 1171CytoplasmicCombined sources1 PublicationAdd BLAST63
Transmembranei1172 – 1189Helical; Name=S1 of repeat IVCombined sources1 PublicationAdd BLAST18
Topological domaini1190 – 1200ExtracellularCombined sources1 PublicationAdd BLAST11
Transmembranei1201 – 1219Helical; Name=S2 of repeat IVCombined sources1 PublicationAdd BLAST19
Topological domaini1220 – 1231CytoplasmicCombined sources1 PublicationAdd BLAST12
Transmembranei1232 – 1249Helical; Name=S3 of repeat IVCombined sources1 PublicationAdd BLAST18
Topological domaini1250 – 1262ExtracellularCombined sources1 PublicationAdd BLAST13
Transmembranei1263 – 1279Helical; Name=S4 of repeat IVCombined sources1 PublicationAdd BLAST17
Topological domaini1280 – 1298CytoplasmicCombined sources1 PublicationAdd BLAST19
Transmembranei1299 – 1316Helical; Name=S5 of repeat IVCombined sources1 PublicationAdd BLAST18
Topological domaini1317 – 1338ExtracellularCombined sources1 PublicationAdd BLAST22
Intramembranei1339 – 1361Pore-formingCombined sources1 PublicationAdd BLAST23
Topological domaini1362 – 1387ExtracellularCombined sources1 PublicationAdd BLAST26
Transmembranei1388 – 1410Helical; Name=S6 of repeat IVCombined sources1 PublicationAdd BLAST23
Topological domaini1411 – 1553CytoplasmicCombined sources1 PublicationAdd BLAST143

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004397621 – 1553Sodium channel protein PaFPC1Add BLAST1553

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi288 ↔ 337Combined sources1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi300N-linked (GlcNAc...) asparagineCombined sources1 Publication1
Glycosylationi308N-linked (GlcNAc...) asparagineCombined sources1 Publication1
Glycosylationi312N-linked (GlcNAc...) asparagineCombined sources1 Publication1
Glycosylationi330N-linked (GlcNAc...) asparagineCombined sources1 Publication1
Glycosylationi683N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi709 ↔ 717Combined sources1 Publication
Disulfide bondi1011 ↔ 1030Combined sources1 Publication
Glycosylationi1015N-linked (GlcNAc...) asparagineCombined sources1 Publication1
Glycosylationi1028N-linked (GlcNAc...) asparagine; atypicalCombined sources1 Publication1
Glycosylationi1034N-linked (GlcNAc...) asparagineCombined sources1 Publication1
Glycosylationi1301N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi1368 ↔ 1381Combined sources1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
D0E0C2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in adult nerve cord, muscle, gut and mushroom-shaped accessory glands.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
D0E0C2, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11553
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
D0E0C2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1133 – 1146Linker region that may regulate channel inactivation1 PublicationAdd BLAST14

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The sequence contains 4 internal repeats, each with 5 hydrophobic segments (S1, S2, S3, S5, S6) and one positively charged segment (S4). Segments S4 are probably the voltage-sensors and are characterized by a series of positively charged amino acids at every third position.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sodium channel (TC 1.A.1.10) family. [View classification]UniRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031649 GPHH_dom
IPR005821 Ion_trans_dom
IPR001696 Na_channel_asu
IPR027359 Volt_channel_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16905 GPHH, 1 hit
PF00520 Ion_trans, 4 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00170 NACHANNEL

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D0E0C2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADNSPLIRE ERQRLFRPYT RAMLTAPSAQ PAKENGKTEE NKDNSRDKGR
60 70 80 90 100
GANKDRDGSA HPDQALEQGS RLPARMRNIF PAELASTPLE DFDPFYKNKK
110 120 130 140 150
TFVVVTKAGD IFRFSGEKSL WMLDPFTPIR RVAISTMVQP IFSYFIMITI
160 170 180 190 200
LIHCIFMIMP ATQTTYILEL VFLSIYTIEV VVKVLARGFI LHPFAYLRDP
210 220 230 240 250
WNWLDFLVTL IGYITLVVDL GHLYALRAFR VLRSWRTVTI VPGWRTIVDA
260 270 280 290 300
LSLSITSLKD LVLLLLFSLF VFAVLGLQIY MGVLTQKCVK HFPADGSWGN
310 320 330 340 350
FTDERWFNYT SNSSHWYIPD DWIEYPLCGN SSGAGMCPPG YTCLQGYGGN
360 370 380 390 400
PNYGYTSFDT FGWAFLSVFR LVTLDYWEDL YQLALRSAGP WHILFFIIVV
410 420 430 440 450
FYGTFCFLNF ILAVVVMSYT HMVKRADEEK AAERELKKEK KAASVANNTA
460 470 480 490 500
NGQEQTTIEM NGDEAVVIDN NDQAARQQSD PETPAPSVTQ RLTDFLCVWD
510 520 530 540 550
CCVPWQKLQG AIGAVVLSPF FELFIAVIIV LNITFMALDH HDMNIEFERI
560 570 580 590 600
LRTGNYIFTS IYIVEAVLKI IALSPKFYFK DSWNVFDFII VVFAILELGL
610 620 630 640 650
EGVQGLSVFR SFRLLRVFRL AKFWPTLNNF MSVMTKSYGA FVNVMYVMFL
660 670 680 690 700
LLFIFAIIGM QLFGMNYIDN MERFPDGDLP RWNFTDFLHS FMIVFRALCG
710 720 730 740 750
EWIESMWDCM LVGDWSCIPF FVAVFFVGNL VILNLLIALL LNNYGSFCTS
760 770 780 790 800
PTSDEEDSKD EDALAQIVRI FKRFKPNLNA VKLSPMKPDS EDIVESQEIQ
810 820 830 840 850
GNNIADAEDV LAGEFPPDCC CNAFYKCFPS RPARDSSVQR MWSNIRRVCF
860 870 880 890 900
LLAKNKYFQK FVTAVLVITS VLLALEDIYL PQRPVLVNIT LYVDYVLTAF
910 920 930 940 950
FVIEMIIMLF AVGFKKYFTS KWYWLDFIVV VAYLLNFVLM CAGIEALQTL
960 970 980 990 1000
RLLRVFRLFR PLSKVNGMQV VTSTLVEAVP HIFNVILVGI FFWLVFAIMG
1010 1020 1030 1040 1050
VQLFAGKFYK CVDENSTVLS HEITMDRNDC LHENYTWENS PMNFDHVGNA
1060 1070 1080 1090 1100
YLSLLQVATF KGWLQIMNDA IDSREVHKQP IRETNIYMYL YFIFFIVFGS
1110 1120 1130 1140 1150
FFILKLFVCI LIDIFRQQRR KAEGLSATDS RTQLIYRRAV MRTMSAKPVK
1160 1170 1180 1190 1200
RIPKPTCHPQ SLMYDISVNR KFEYTMMILI ILNVAVMAID HYGQSMEFSE
1210 1220 1230 1240 1250
VLDYLNLIFI IIFFVECVIK VSGLRHHYFK DPWNIIDFLY VVLAIAGLML
1260 1270 1280 1290 1300
SDVIEKYFIS PTLLRILRIL RVGRLLRYFQ SARGMRLLLL ALRKALRTLF
1310 1320 1330 1340 1350
NVSFLLFVIM FVYAVFGMEF FMHIRDAGAI DDVYNFKTFG QSIILLFQLA
1360 1370 1380 1390 1400
TSAGWDGVYF AIANEEDCRA PDHELGYPGN CGSRALGIAY LVSYLIITCL
1410 1420 1430 1440 1450
VVINMYAAVI LDYVLEVYED SKEGLTDDDY DMFFEVWQQF DPEATQYIRY
1460 1470 1480 1490 1500
DQLSELLEAL QPPLQVQKPN KYKILSMNIP ICKDDHIFYK DVLEALVKDV
1510 1520 1530 1540 1550
FSRRGSPVEA GDVQAPNVDE AEYKPVSSTL QRQREEYCVR LIQNAWRKHK

QQN
Length:1,553
Mass (Da):179,116
Last modified:November 24, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i62CBCDA0A59D61D5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GQ132120 mRNA Translation: ACX44802.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ132120 mRNA Translation: ACX44802.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5X0Melectron microscopy3.80A1-1553[»]
6A90electron microscopy2.80A1-1553[»]
6A91electron microscopy3.20A1-1553[»]
6A95electron microscopy2.60A1-1553[»]
6NT3electron microscopy3.40A1-269[»]
A289-1155[»]
A1287-1505[»]
6NT4electron microscopy3.50A1-269[»]
A289-1155[»]
A1287-1505[»]
SMRiD0E0C2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiD0E0C2, 1 interactor

Protein family/group databases

TCDBi1.A.1.10.20 the voltage-gated ion channel (vic) superfamily

PTM databases

iPTMnetiD0E0C2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.20.120.350, 4 hits
InterProiView protein in InterPro
IPR031649 GPHH_dom
IPR005821 Ion_trans_dom
IPR001696 Na_channel_asu
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF16905 GPHH, 1 hit
PF00520 Ion_trans, 4 hits
PRINTSiPR00170 NACHANNEL

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCNA1_PERAM
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D0E0C2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2017
Last sequence update: November 24, 2009
Last modified: June 5, 2019
This is version 50 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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