UniProtKB - C9JZR2 (C9JZR2_HUMAN)
Protein
Submitted name:
Catenin delta-1
Gene
CTNND1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- cadherin binding Source: InterPro
GO - Biological processi
- cell-cell adhesion Source: InterPro
Keywordsi
Biological process | Cell adhesionARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Catenin delta-1Imported |
Gene namesi | Name:CTNND1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:2515, CTNND1 |
VEuPathDBi | HostDB:ENSG00000198561.13 |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: HPA
Other locations
- cell junction Source: UniProtKB-KW
Keywords - Cellular componenti
Cell junctionARBA annotationPTM / Processingi
Proteomic databases
EPDi | C9JZR2 |
MaxQBi | C9JZR2 |
PeptideAtlasi | C9JZR2 |
PRIDEi | C9JZR2 |
ProteomicsDBi | 12430 |
PTM databases
SwissPalmi | C9JZR2 |
Expressioni
Gene expression databases
Bgeei | ENSG00000198561, Expressed in ventricular zone and 244 other tissues |
ExpressionAtlasi | C9JZR2, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 408 – 445 | ARMPROSITE-ProRule annotationAdd BLAST | 38 | |
Repeati | 451 – 494 | ARMPROSITE-ProRule annotationAdd BLAST | 44 | |
Repeati | 710 – 747 | ARMPROSITE-ProRule annotationAdd BLAST | 38 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 855 – 938 | DisorderedSequence analysisAdd BLAST | 84 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 13 – 36 | Sequence analysisAdd BLAST | 24 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 855 – 872 | PolarSequence analysisAdd BLAST | 18 | |
Compositional biasi | 873 – 888 | PolyampholyteSequence analysisAdd BLAST | 16 | |
Compositional biasi | 889 – 910 | PolarSequence analysisAdd BLAST | 22 | |
Compositional biasi | 911 – 925 | PolyampholyteSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Belongs to the beta-catenin family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000156045 |
OMAi | GDQMSYP |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR000225, Armadillo IPR028439, Catenin_d1 IPR028435, Plakophilin/d_Catenin |
PANTHERi | PTHR10372, PTHR10372, 1 hit PTHR10372:SF6, PTHR10372:SF6, 1 hit |
Pfami | View protein in Pfam PF00514, Arm, 3 hits |
SMARTi | View protein in SMART SM00185, ARM, 7 hits |
SUPFAMi | SSF48371, SSF48371, 1 hit |
PROSITEi | View protein in PROSITE PS50176, ARM_REPEAT, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
C9JZR2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDDSEVESTA SILASVKEQE AQFEKLTRAL EEERRHVSAQ LERVRVSPQD
60 70 80 90 100
ANPLMANGTL TRRHQNGRFV GDADLERQKF SDLKLNGPQD HSHLLYSTIP
110 120 130 140 150
RMQEPGQIVE TYTEEDPEGA MSVVSVETSD DGTTRRTETT VKKVVKTVTT
160 170 180 190 200
RTVQPVAMGP DGLPVDASSV SNNYIQTLGR DFRKNGNGGP GPYVGQAGTA
210 220 230 240 250
TLPRNFHYPP DGYSRHYEDG YPGGSDNYGS LSRVTRIEER YRPSMEGYRA
260 270 280 290 300
PSRQDVYGPQ PQVRVGGSSV DLHRFHPEPY GLEDDQRSMG YDDLDYGMMS
310 320 330 340 350
DYGTARRTGT PSDPRRRLRS YEDMIGEEVP SDQYYWAPLA QHERGSLASL
360 370 380 390 400
DSLRKGGPPP PNWRQPELPE VIAMLGFRLD AVKSNAAAYL QHLCYRNDKV
410 420 430 440 450
KTDVRKLKGI PVLVGLLDHP KKEVHLGACG ALKNISFGRD QDNKIAIKNC
460 470 480 490 500
DGVPALVRLL RKARDMDLTE VITGTLWNLS SHDSIKMEIV DHALHALTDE
510 520 530 540 550
VIIPHSGWER EPNEDCKPRH IEWESVLTNT AGCLRNVSSE RSEARRKLRE
560 570 580 590 600
CDGLVDALIF IVQAEIGQKD SDSKLVENCV CLLRNLSYQV HREIPQAERY
610 620 630 640 650
QEAAPNVANN TGPHAASCFG AKKGKDEWFS RGKKPIEDPA NDTVDFPKRT
660 670 680 690 700
SPARGYELLF QPEVVRIYIS LLKESKTPAI LEASAGAIQN LCAGRWTYGR
710 720 730 740 750
YIRSALRQEK ALSAIADLLT NEHERVVKAA SGALRNLAVD ARNKELIGKH
760 770 780 790 800
AIPNLVKNLP GGQQNSSWNF SEDTVISILN TINEVIAENL EAAKKLRETQ
810 820 830 840 850
GIEKLVLINK SGNRSEKEVR AAALVLQTIW GYKELRKPLE KEGWKKSDFQ
860 870 880 890 900
VNLNNASRSQ SSHSYDDSTL PLIDRNQKSD KKPDREEIQM SNMGSNTKSL
910 920 930
DNNYSTPNER GDHNRTLDRS GDLGDMEPLK GTTPLMKI
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO60716 | CTND1_HUMAN | Catenin delta-1 | CTNND1 KIAA0384 | 968 | Annotation score: | ||
A0A669KB05 | A0A669KB05_HUMAN | Catenin delta-1 | CTNND1 | 915 | Annotation score: | ||
A0A669KB62 | A0A669KB62_HUMAN | Catenin delta-1 | CTNND1 | 888 | Annotation score: | ||
E9PKY0 | E9PKY0_HUMAN | Catenin delta-1 | CTNND1 | 126 | Annotation score: | ||
H0YC95 | H0YC95_HUMAN | Catenin delta-1 | CTNND1 | 123 | Annotation score: | ||
E9PKL1 | E9PKL1_HUMAN | Catenin delta-1 | CTNND1 | 128 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP001931 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000529919; ENSP00000434808; ENSG00000198561 |
UCSCi | uc001nlh.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP001931 Genomic DNA No translation available. |
3D structure databases
SMRi | C9JZR2 |
ModBasei | Search... |
PTM databases
SwissPalmi | C9JZR2 |
Proteomic databases
EPDi | C9JZR2 |
MaxQBi | C9JZR2 |
PeptideAtlasi | C9JZR2 |
PRIDEi | C9JZR2 |
ProteomicsDBi | 12430 |
Protocols and materials databases
Antibodypediai | 2886, 1068 antibodies |
Genome annotation databases
Ensembli | ENST00000529919; ENSP00000434808; ENSG00000198561 |
UCSCi | uc001nlh.2, human |
Organism-specific databases
HGNCi | HGNC:2515, CTNND1 |
OpenTargetsi | ENSG00000198561 |
VEuPathDBi | HostDB:ENSG00000198561.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156045 |
OMAi | GDQMSYP |
Miscellaneous databases
ChiTaRSi | CTNND1, human |
Gene expression databases
Bgeei | ENSG00000198561, Expressed in ventricular zone and 244 other tissues |
ExpressionAtlasi | C9JZR2, baseline and differential |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR000225, Armadillo IPR028439, Catenin_d1 IPR028435, Plakophilin/d_Catenin |
PANTHERi | PTHR10372, PTHR10372, 1 hit PTHR10372:SF6, PTHR10372:SF6, 1 hit |
Pfami | View protein in Pfam PF00514, Arm, 3 hits |
SMARTi | View protein in SMART SM00185, ARM, 7 hits |
SUPFAMi | SSF48371, SSF48371, 1 hit |
PROSITEi | View protein in PROSITE PS50176, ARM_REPEAT, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9JZR2_HUMAN | |
Accessioni | C9JZR2Primary (citable) accession number: C9JZR2 Secondary accession number(s): E9PN49 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | June 28, 2011 | |
Last modified: | April 7, 2021 | |
This is version 98 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |