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Protein
Submitted name:

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

Gene

GNB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiC9JZN1

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2Imported
Gene namesi
Name:GNB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000172354.9
HGNCiHGNC:4398 GNB2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172354

PTM / Processingi

Proteomic databases

MaxQBiC9JZN1
PeptideAtlasiC9JZN1
PRIDEiC9JZN1

Expressioni

Gene expression databases

BgeeiENSG00000172354 Expressed in 224 organ(s), highest expression level in blood
ExpressionAtlasiC9JZN1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JZN1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 152WD_REPEATS_REGIONInterPro annotationAdd BLAST102
Repeati51 – 92WDPROSITE-ProRule annotationAdd BLAST42

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 24Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, WD repeatPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0286 Eukaryota
ENOG410XQUX LUCA
GeneTreeiENSGT00760000119239
HOGENOMiHOG000176356

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR19850 PTHR19850, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 2 hits
PRINTSiPR00319 GPROTEINB
SMARTiView protein in SMART
SM00320 WD40, 2 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 1 hit
PS50294 WD_REPEATS_REGION, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

C9JZN1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSELEQLRQE AEQLRNQIRD ARKACGDSTL TQITAGLDPV GRIQMRTRRT
60 70 80 90 100
LRGHLAKIYA MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV
110 120 130 140 150
MTCAYAPSGN FVACGGLDNI CSIYSLKTRE GNVRVSRELP GHTGYLSCCR

FL
Length:152
Mass (Da):17,033
Last modified:November 3, 2009 - v1
Checksum:i2B9E6B4952BC1877
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P62879GBB2_HUMAN
Guanine nucleotide-binding protein ...
GNB2
340Annotation score:
C9JXA5C9JXA5_HUMAN
Guanine nucleotide-binding protein ...
GNB2
251Annotation score:
C9JIS1C9JIS1_HUMAN
Guanine nucleotide-binding protein ...
GNB2
232Annotation score:
E7EP32E7EP32_HUMAN
Guanine nucleotide-binding protein ...
GNB2
296Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei152Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009488 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000412215; ENSP00000413219; ENSG00000172354
UCSCiuc064ghb.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009488 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JZN1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9JZN1
PeptideAtlasiC9JZN1
PRIDEiC9JZN1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000412215; ENSP00000413219; ENSG00000172354
UCSCiuc064ghb.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000172354.9
HGNCiHGNC:4398 GNB2
OpenTargetsiENSG00000172354
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0286 Eukaryota
ENOG410XQUX LUCA
GeneTreeiENSGT00760000119239
HOGENOMiHOG000176356

Enzyme and pathway databases

SignaLinkiC9JZN1

Miscellaneous databases

ChiTaRSiGNB2 human

Gene expression databases

BgeeiENSG00000172354 Expressed in 224 organ(s), highest expression level in blood
ExpressionAtlasiC9JZN1 baseline and differential

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR19850 PTHR19850, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 2 hits
PRINTSiPR00319 GPROTEINB
SMARTiView protein in SMART
SM00320 WD40, 2 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 1 hit
PS50294 WD_REPEATS_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JZN1_HUMAN
AccessioniPrimary (citable) accession number: C9JZN1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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