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Protein
Submitted name:

E3 ubiquitin-protein ligase Midline-1

Gene

MID1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
E3 ubiquitin-protein ligase Midline-1Imported
Gene namesi
Name:MID1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000101871.14
HGNCiHGNC:7095 MID1

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101871

PTM / Processingi

Proteomic databases

MaxQBiC9JZJ7
PeptideAtlasiC9JZJ7
PRIDEiC9JZJ7

Expressioni

Gene expression databases

BgeeiENSG00000101871 Expressed in 231 organ(s), highest expression level in hair follicle
ExpressionAtlasiC9JZJ7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JZJ7
SMRiC9JZJ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 60RING-typeInterPro annotationAdd BLAST51

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410ITFU Eukaryota
ENOG410Z43Q LUCA
GeneTreeiENSGT00760000118878
HOGENOMiHOG000170021

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR027727 MID1
IPR027370 Znf-RING_LisH
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR44073:SF3 PTHR44073:SF3, 1 hit
PfamiView protein in Pfam
PF13445 zf-RING_UBOX, 1 hit
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

C9JZJ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METLESELTC PICLELFEDP LLLPCAHSLC FNCAHRILVS HCATNESVES
60 70 80 90 100
ITAFQCPTCR HVITLSQRGL DGLKRNVTLQ NIIDRFQKAS VSGPNSPSET
110 120 130 140 150
RRERAFDANT MTSAEKVLCQ FCDQDPAQDA VKTCVTCEVS YCDECLKATH
160 170 180 190
PNKKPFTGHR LIEPIPDSHI RGLMCLEHED EKVNMYCVTD DQLICAL
Length:197
Mass (Da):22,062
Last modified:November 3, 2009 - v1
Checksum:iA4AD37F5ACC85578
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O15344TRI18_HUMAN
E3 ubiquitin-protein ligase Midline...
MID1 FXY, RNF59, TRIM18, XPRF
667Annotation score:
A0A087X255A0A087X255_HUMAN
E3 ubiquitin-protein ligase Midline...
MID1
540Annotation score:
A0A087X0X0A0A087X0X0_HUMAN
E3 ubiquitin-protein ligase Midline...
MID1
228Annotation score:
C9J453C9J453_HUMAN
E3 ubiquitin-protein ligase Midline...
MID1
483Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei197Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002349 Genomic DNA No translation available.
AC008008 Genomic DNA No translation available.
AC117406 Genomic DNA No translation available.
KC877957 Genomic DNA No translation available.
U96409 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000423614; ENSP00000387771; ENSG00000101871
UCSCiuc064xyr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002349 Genomic DNA No translation available.
AC008008 Genomic DNA No translation available.
AC117406 Genomic DNA No translation available.
KC877957 Genomic DNA No translation available.
U96409 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JZJ7
SMRiC9JZJ7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9JZJ7
PeptideAtlasiC9JZJ7
PRIDEiC9JZJ7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000423614; ENSP00000387771; ENSG00000101871
UCSCiuc064xyr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000101871.14
HGNCiHGNC:7095 MID1
OpenTargetsiENSG00000101871
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410ITFU Eukaryota
ENOG410Z43Q LUCA
GeneTreeiENSGT00760000118878
HOGENOMiHOG000170021

Miscellaneous databases

ChiTaRSiMID1 human

Gene expression databases

BgeeiENSG00000101871 Expressed in 231 organ(s), highest expression level in hair follicle
ExpressionAtlasiC9JZJ7 baseline and differential

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR027727 MID1
IPR027370 Znf-RING_LisH
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR44073:SF3 PTHR44073:SF3, 1 hit
PfamiView protein in Pfam
PF13445 zf-RING_UBOX, 1 hit
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JZJ7_HUMAN
AccessioniPrimary (citable) accession number: C9JZJ7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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