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Protein
Submitted name:

Kinesin light chain 4

Gene

KLC4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin light chain 4Imported
Gene namesi
Name:KLC4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000137171.14
HGNCiHGNC:21624 KLC4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000137171

PTM / Processingi

Proteomic databases

MaxQBiC9JZE5
PeptideAtlasiC9JZE5
PRIDEiC9JZE5

Expressioni

Gene expression databases

BgeeiENSG00000137171 Expressed in 190 organ(s), highest expression level in right lobe of liver
ExpressionAtlasiC9JZE5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JZE5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili8 – 63Sequence analysisAdd BLAST56

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1840 Eukaryota
COG0457 LUCA
GeneTreeiENSGT00390000006393
HOGENOMiHOG000261663

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR002151 Kinesin_light
IPR011990 TPR-like_helical_dom_sf
PRINTSiPR00381 KINESINLIGHT

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

C9JZE5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLALASHLST VESEKQKLRA QVRRLCQENQ WLRDELAGTQ QRLQRSEQAV
60 70 80 90 100
AQLEEEKKHL EFLGQLRQYD EDGHTSEEKE GDATKDSLDD LFPNEEEEDP
110 120 130 140 150
SNGLSRGQGA TAAQQGGYEI PARLRTLHNL VIQYAAQGRY EVAVPLCKQA
160
LEDLERTSGR GH
Length:162
Mass (Da):18,312
Last modified:November 3, 2009 - v1
Checksum:i52ADB50A37ECFE4D
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NSK0KLC4_HUMAN
Kinesin light chain 4
KLC4 KNSL8
619Annotation score:
C9J8T5C9J8T5_HUMAN
Kinesin light chain 4
KLC4
271Annotation score:
H7C4M1H7C4M1_HUMAN
Kinesin light chain 4
KLC4
159Annotation score:
C9JQU1C9JQU1_HUMAN
Kinesin light chain 4
KLC4
84Annotation score:
C9JXT5C9JXT5_HUMAN
Kinesin light chain 4
KLC4
82Annotation score:
C9K0D5C9K0D5_HUMAN
Kinesin light chain 4
KLC4
91Annotation score:
F8WCA4F8WCA4_HUMAN
Kinesin light chain 4
KLC4
45Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei162Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136304 Genomic DNA No translation available.
AL355385 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000479632; ENSP00000419784; ENSG00000137171
UCSCiuc063opd.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136304 Genomic DNA No translation available.
AL355385 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JZE5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9JZE5
PeptideAtlasiC9JZE5
PRIDEiC9JZE5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000479632; ENSP00000419784; ENSG00000137171
UCSCiuc063opd.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000137171.14
HGNCiHGNC:21624 KLC4
OpenTargetsiENSG00000137171
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1840 Eukaryota
COG0457 LUCA
GeneTreeiENSGT00390000006393
HOGENOMiHOG000261663

Miscellaneous databases

ChiTaRSiKLC4 human

Gene expression databases

BgeeiENSG00000137171 Expressed in 190 organ(s), highest expression level in right lobe of liver
ExpressionAtlasiC9JZE5 baseline and differential

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR002151 Kinesin_light
IPR011990 TPR-like_helical_dom_sf
PRINTSiPR00381 KINESINLIGHT
ProtoNetiSearch...

Entry informationi

Entry nameiC9JZE5_HUMAN
AccessioniPrimary (citable) accession number: C9JZE5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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