UniProtKB - C9JZ61 (C9JZ61_HUMAN)
Protein
Submitted name:
Ankyrin repeat domain-containing protein 53
Gene
ANKRD53
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Ankyrin repeat domain-containing protein 53Imported |
Gene namesi | ORF Names:hCG_1646835Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000144031.11 |
HGNCi | HGNC:25691, ANKRD53 |
Expressioni
Gene expression databases
Bgeei | ENSG00000144031, Expressed in quadriceps femoris and 148 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 72 – 229 | ANK_REP_REGIONInterPro annotationAdd BLAST | 158 | |
Repeati | 139 – 175 | ANKPROSITE-ProRule annotationAdd BLAST | 37 | |
Repeati | 176 – 208 | ANKPROSITE-ProRule annotationAdd BLAST | 33 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 65 | DisorderedSequence analysisAdd BLAST | 65 | |
Regioni | 289 – 326 | DisorderedSequence analysisAdd BLAST | 38 | |
Regioni | 349 – 368 | DisorderedSequence analysisAdd BLAST | 20 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 30 – 65 | PolarSequence analysisAdd BLAST | 36 | |
Compositional biasi | 291 – 309 | PolarSequence analysisAdd BLAST | 19 |
Keywords - Domaini
ANK repeatPROSITE-ProRule annotationARBA annotation, RepeatARBA annotationPhylogenomic databases
GeneTreei | ENSGT00390000005650 |
HOGENOMi | CLU_038440_0_0_1 |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR042335, ANKRD53 IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf |
PANTHERi | PTHR24160, PTHR24160, 1 hit |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 3 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
C9JZ61-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASAGSTARR AGSGSWHSER GEGRGARPQP TPSGSMQQAN KVSLKATWTD
60 70 80 90 100
AESKQPSPSK ESDQTAIDQT AIGSYYQLFA AAVGNVEWLR FCLNQSLREI
110 120 130 140 150
PTDDKGFTAI HFAAQWGKLA CLQVLVEEYK FPVDLLTNNS QTPLHLVIHR
160 170 180 190 200
DNTTVALPCI YYLLEKGADL NAQTCNGSTP LHLAARDGLL DCVKVLVQSG
210 220 230 240 250
ANVHAQDAMG YKPIDFCKIW NHRACARFLK DAMWKKDKKD FAREMTKMKM
260 270 280 290 300
FKSQLTLMEH NYLIEYQKEH KILREAAIRK WLHGKLHPGH SLVSNTKQAR
310 320 330 340 350
ATALSKTPEQ RESQRSRSFH PSVDARLQCI PQPTEMPKPI YRKPTVKRPT
360 370 380 390 400
MWNVSNNPAR PPTTQISHSQ GIRLGVHPDP TPEHDFSSFL EVRPDGHGGA
410 420 430 440 450
RLHTVDGHWV APVPRLPFEV LLRMLYPRVW PYRMKVPQGF YPISMREVPR
460 470 480 490
KRHLGDNTFW TDTLAMNLRD TFDEAFLAAV RSHQGLPTLP SPQTNP
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8N9V6 | ANR53_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD53 | 530 | Annotation score: | ||
C9JQK2 | C9JQK2_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD53 | 254 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007040 Genomic DNA No translation available. CH471053 Genomic DNA Translation: EAW99789.1 |
RefSeqi | XP_005264626.1, XM_005264569.4 |
Genome annotation databases
Ensembli | ENST00000457410; ENSP00000407004; ENSG00000144031 |
UCSCi | uc061kkm.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007040 Genomic DNA No translation available. CH471053 Genomic DNA Translation: EAW99789.1 |
RefSeqi | XP_005264626.1, XM_005264569.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PRIDEi | C9JZ61 |
ProteomicsDBi | 12354 |
Protocols and materials databases
Antibodypediai | 53588, 158 antibodies |
Genome annotation databases
Ensembli | ENST00000457410; ENSP00000407004; ENSG00000144031 |
UCSCi | uc061kkm.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000144031.11 |
HGNCi | HGNC:25691, ANKRD53 |
OpenTargetsi | ENSG00000144031 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000005650 |
HOGENOMi | CLU_038440_0_0_1 |
Miscellaneous databases
BioGRID-ORCSi | 79998, 8 hits in 836 CRISPR screens |
ChiTaRSi | ANKRD53, human |
GenomeRNAii | 79998 |
Gene expression databases
Bgeei | ENSG00000144031, Expressed in quadriceps femoris and 148 other tissues |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR042335, ANKRD53 IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf |
PANTHERi | PTHR24160, PTHR24160, 1 hit |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 3 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9JZ61_HUMAN | |
Accessioni | C9JZ61Primary (citable) accession number: C9JZ61 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | December 2, 2020 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |