UniProtKB - C9JYS6 (C9JYS6_HUMAN)
Protein
Submitted name:
Epidermal growth factor receptor
Gene
EGFR
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Epidermal growth factor receptorImported |
Gene namesi | Name:EGFRImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:3236, EGFR |
VEuPathDBi | HostDB:ENSG00000146648.15 |
PTM / Processingi
Proteomic databases
MaxQBi | C9JYS6 |
PeptideAtlasi | C9JYS6 |
PRIDEi | C9JYS6 |
ProteomicsDBi | 12298 |
Expressioni
Gene expression databases
Bgeei | ENSG00000146648, Expressed in placenta and 242 other tissues |
ExpressionAtlasi | C9JYS6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 114 | Recep_L_domainInterPro annotationAdd BLAST | 111 |
Phylogenomic databases
GeneTreei | ENSGT00940000155450 |
HOGENOMi | CLU_128272_0_0_1 |
Family and domain databases
Gene3Di | 3.80.20.20, 1 hit |
InterProi | View protein in InterPro IPR000494, Rcpt_L-dom IPR036941, Rcpt_L-dom_sf |
Pfami | View protein in Pfam PF01030, Recep_L_domain, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
C9JYS6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFNNCEVVLG NLEITYVQRN YDLSFLKTIQ EVAGYVLIAL NTVERIPLEN
60 70 80 90 100
LQIIRGNMYY ENSYALAVLS NYDANKTGLK ELPMRNLQEI LHGAVRFSNN
110 120
PALCNVESIQ WRDIVSSDFL SNMSMDFQ
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP00533 | EGFR_HUMAN | Epidermal growth factor receptor | EGFR ERBB, ERBB1, HER1 | 1,210 | Annotation score: | ||
E9PFD7 | E9PFD7_HUMAN | Receptor protein-tyrosine kinase | EGFR | 1,165 | Annotation score: | ||
Q504U8 | Q504U8_HUMAN | Receptor protein-tyrosine kinase | EGFR | 1,091 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 128 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC006977 Genomic DNA No translation available. AC073324 Genomic DNA No translation available. KF458469 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000450046; ENSP00000413354; ENSG00000146648 |
UCSCi | uc064dsn.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC006977 Genomic DNA No translation available. AC073324 Genomic DNA No translation available. KF458469 Genomic DNA No translation available. |
3D structure databases
SMRi | C9JYS6 |
ModBasei | Search... |
Proteomic databases
MaxQBi | C9JYS6 |
PeptideAtlasi | C9JYS6 |
PRIDEi | C9JYS6 |
ProteomicsDBi | 12298 |
Protocols and materials databases
Antibodypediai | 718, 9511 antibodies |
Genome annotation databases
Ensembli | ENST00000450046; ENSP00000413354; ENSG00000146648 |
UCSCi | uc064dsn.1, human |
Organism-specific databases
HGNCi | HGNC:3236, EGFR |
OpenTargetsi | ENSG00000146648 |
VEuPathDBi | HostDB:ENSG00000146648.15 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155450 |
HOGENOMi | CLU_128272_0_0_1 |
Miscellaneous databases
ChiTaRSi | EGFR, human |
Gene expression databases
Bgeei | ENSG00000146648, Expressed in placenta and 242 other tissues |
ExpressionAtlasi | C9JYS6, baseline and differential |
Family and domain databases
Gene3Di | 3.80.20.20, 1 hit |
InterProi | View protein in InterPro IPR000494, Rcpt_L-dom IPR036941, Rcpt_L-dom_sf |
Pfami | View protein in Pfam PF01030, Recep_L_domain, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9JYS6_HUMAN | |
Accessioni | C9JYS6Primary (citable) accession number: C9JYS6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | April 7, 2021 | |
This is version 71 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |