Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Nucleoporin-like protein 2

Gene

NUPL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1 – 25C3H1-typePROSITE-ProRule annotationAdd BLAST25

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleoporin-like protein 2Imported
Gene namesi
Name:NUPL2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000136243.16
HGNCiHGNC:17010 NUPL2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000136243

PTM / Processingi

Proteomic databases

EPDiC9JYA1
MaxQBiC9JYA1
PeptideAtlasiC9JYA1
PRIDEiC9JYA1

Expressioni

Gene expression databases

BgeeiENSG00000136243 Expressed in 217 organ(s), highest expression level in kidney
ExpressionAtlasiC9JYA1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JYA1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 25C3H1-typeInterPro annotationAdd BLAST25

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili175 – 195Sequence analysisAdd BLAST21

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1 – 25C3H1-typePROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000000118
HOGENOMiHOG000113895
OMAiDMEIWES
OrthoDBiEOG091G0WSZ
PhylomeDBiC9JYA1

Family and domain databases

InterProiView protein in InterPro
IPR000571 Znf_CCCH
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 1 hit
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

C9JYA1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAICQFFLQG RCRFGDRCWN EHPGARGAGG GRQQPQQQPS GNNRRGWNTT
60 70 80 90 100
SQRYSNVIQP SSFSKSTPWG GSRDQEKPYF SSFDSGASTN RKEGFGLSEN
110 120 130 140 150
PFASLSPDEQ KDEKKLLEGI VKDMEVWESS GQWMFSVYSP VKKKPNISGF
160 170 180 190 200
TDISPEELRL EYHNFLTSNN LQSYLNSVQR LINQWRNRVN ELKSLNISTK
210 220 230 240 250
VALKCLWKIY THLSPKIYGP DCGKFIIFLS DVKDGVNQAA PAFGFGSSQA
260 270 280 290 300
ATFMSPGFPV NNSSSDNAQN FSFKTNSGFA AASSGSPAGF GSSPAFGAAA
310 320 330 340 350
STSSGISTSA PAFGFGKPEV TSAASFSFKS PAASSFGSPG FSGLPASLAT
360 370 380 390 400
GPVRAPVAPA FGGGSSVAGF GSPGSHSHTA FSKPSSDTFG NSSISTSLSA
410 420 430
SSSIIATDNV LFTPRDKLTV EELEQFQSKK FTLGK
Length:435
Mass (Da):46,400
Last modified:November 3, 2009 - v1
Checksum:i1B98C46AB76EE5A9
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O15504NUPL2_HUMAN
Nucleoporin-like protein 2
NUPL2 CG1
423Annotation score:
B4DT96B4DT96_HUMAN
Nucleoporin-like protein 2
NUPL2
155Annotation score:
F8WC66F8WC66_HUMAN
Nucleoporin-like protein 2
NUPL2
44Annotation score:
A0A087WZL5A0A087WZL5_HUMAN
Nucleoporin-like protein 2
NUPL2
83Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei435Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005082 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000413919; ENSP00000401475; ENSG00000136243
UCSCiuc064bzf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005082 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JYA1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiC9JYA1
MaxQBiC9JYA1
PeptideAtlasiC9JYA1
PRIDEiC9JYA1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413919; ENSP00000401475; ENSG00000136243
UCSCiuc064bzf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000136243.16
HGNCiHGNC:17010 NUPL2
OpenTargetsiENSG00000136243
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000000118
HOGENOMiHOG000113895
OMAiDMEIWES
OrthoDBiEOG091G0WSZ
PhylomeDBiC9JYA1

Miscellaneous databases

ChiTaRSiNUPL2 human

Gene expression databases

BgeeiENSG00000136243 Expressed in 217 organ(s), highest expression level in kidney
ExpressionAtlasiC9JYA1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000571 Znf_CCCH
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 1 hit
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JYA1_HUMAN
AccessioniPrimary (citable) accession number: C9JYA1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: November 7, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again