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Protein
Submitted name:

Transforming protein RhoA

Gene

RHOA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Transforming protein RhoAImported
Gene namesi
Name:RHOAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000067560.10
HGNCiHGNC:667 RHOA

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000067560

PTM / Processingi

Proteomic databases

MaxQBiC9JX21
PeptideAtlasiC9JX21
PRIDEiC9JX21

PTM databases

iPTMnetiC9JX21

Expressioni

Gene expression databases

BgeeiENSG00000067560 Expressed in 243 organ(s), highest expression level in metanephric glomerulus
ExpressionAtlasiC9JX21 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JX21
SMRiC9JX21
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0393 Eukaryota
COG1100 LUCA
GeneTreeiENSGT00760000119020
HOGENOMiHOG000233974

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51420 RHO, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.iShow all

C9JX21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG
60 70 80 90 100
KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT
110 120 130 140 150
PEVKHFCPNV PIILVGNKKD LRNDEHTRRE LAKMKQEPHC VARLECCGTI
160 170 180
LAQLQPPPPR FKRFPCLSLL SSWGYRRPLP HPGAGET
Length:187
Mass (Da):21,164
Last modified:November 3, 2009 - v1
Checksum:iFC5FBC55C61CFE2A
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P61586RHOA_HUMAN
Transforming protein RhoA
RHOA ARH12, ARHA, RHO12
193Annotation score:
C9JNR4C9JNR4_HUMAN
Transforming protein RhoA
RHOA
129Annotation score:
C9JRM1C9JRM1_HUMAN
Transforming protein RhoA
RHOA
90Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104452 Genomic DNA No translation available.
AC121247 Genomic DNA No translation available.
AC137114 Genomic DNA No translation available.
RefSeqiNP_001300872.1, NM_001313943.1
UniGeneiHs.247077

Genome annotation databases

EnsembliENST00000422781; ENSP00000413587; ENSG00000067560
GeneIDi387
UCSCiuc062jtb.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JX21_HUMAN
AccessioniPrimary (citable) accession number: C9JX21
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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