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Protein
Submitted name:

Grancalcin

Gene

GCA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
GrancalcinImported
Gene namesi
Name:GCAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000115271.10
HGNCiHGNC:15990 GCA

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000115271

PTM / Processingi

Proteomic databases

PeptideAtlasiC9JWQ8
PRIDEiC9JWQ8

Expressioni

Gene expression databases

BgeeiENSG00000115271 Expressed in 220 organ(s), highest expression level in bone marrow
ExpressionAtlasiC9JWQ8 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini90 – 145EF-handInterPro annotationAdd BLAST56

Phylogenomic databases

eggNOGiKOG0037 Eukaryota
ENOG410YKQK LUCA
GeneTreeiENSGT00620000087734
HOGENOMiHOG000231982

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13833 EF-hand_8, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

C9JWQ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWRRQEEVLP KINLTSCGFP NTNLFPWEFG GGFEKFGNFS IQVPGMQMGQ
60 70 80 90 100
PVPETGPAIL LDGYSGPAYS DTYSSAGDSV YTYFSAVAGQ DGEVDAEELQ
110 120 130 140
RCLTQSGING TYSPFSLETC RIMIAMLDRD HTGKMGFNAF KELWAA
Length:146
Mass (Da):16,061
Last modified:October 5, 2016 - v8
Checksum:i6F14223A87E31D41
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P28676GRAN_HUMAN
Grancalcin
GCA GCL
217Annotation score:
H7BXD5H7BXD5_HUMAN
Grancalcin
GCA
198Annotation score:
H7C2Z6H7C2Z6_HUMAN
Grancalcin
GCA
146Annotation score:
C9JIZ3C9JIZ3_HUMAN
Grancalcin
GCA
132Annotation score:
C9JV47C9JV47_HUMAN
Grancalcin
GCA
87Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei146Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010876 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000446271; ENSP00000393218; ENSG00000115271
UCSCiuc061paz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010876 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9JWQ8
PRIDEiC9JWQ8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000446271; ENSP00000393218; ENSG00000115271
UCSCiuc061paz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000115271.10
HGNCiHGNC:15990 GCA
OpenTargetsiENSG00000115271
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0037 Eukaryota
ENOG410YKQK LUCA
GeneTreeiENSGT00620000087734
HOGENOMiHOG000231982

Miscellaneous databases

ChiTaRSiGCA human

Gene expression databases

BgeeiENSG00000115271 Expressed in 220 organ(s), highest expression level in bone marrow
ExpressionAtlasiC9JWQ8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13833 EF-hand_8, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JWQ8_HUMAN
AccessioniPrimary (citable) accession number: C9JWQ8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 63 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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