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Protein
Submitted name:

E3 ubiquitin-protein ligase TRIM22

Gene

TRIM22

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
E3 ubiquitin-protein ligase TRIM22Imported
Gene namesi
Name:TRIM22Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000132274.15
HGNCiHGNC:16379 TRIM22

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132274

PTM / Processingi

Proteomic databases

MaxQBiC9JWC5
PeptideAtlasiC9JWC5
PRIDEiC9JWC5

Expressioni

Gene expression databases

BgeeiENSG00000132274 Expressed in 222 organ(s), highest expression level in blood
ExpressionAtlasiC9JWC5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JWC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 60RING-typeInterPro annotationAdd BLAST46
Domaini92 – 133B box-typeInterPro annotationAdd BLAST42

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118893
HOGENOMiHOG000234134

Family and domain databases

CDDicd00021 BBOX, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PfamiView protein in Pfam
PF00643 zf-B_box, 1 hit
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

C9JWC5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDFSVKVDIE KEVTCPICLE LLTEPLSLDC GHSFCQACIT AKIKESVIIS
60 70 80 90 100
RGESSCPVCQ TRFQPGNLRP NRHLANIVER VKEVKMSPQE GQKRDVCEHH
110 120 130 140 150
GKKLQIFCKE DGKVICWVCE LSQEHQGHQT FRINEVVKEC QNYIQIERQK
160 170 180 190 200
ILKGFNEMRV ILDNEEQREL QKLEEGEVNV LDNLAAATDQ LVQQRQDAST
210 220 230 240 250
LISDLQRRLR GSSVEMLQDV IDVMKRSESW TLKKPKSVSK KLKSVFRVPD
260 270 280 290 300
LSGMLQVLKE LTDVQYYWVD VMLNPGSATS NVAISVDQRQ VKTVRTCTFK

NSNPC
Length:305
Mass (Da):34,866
Last modified:November 3, 2009 - v1
Checksum:i8EAC2DBB4D9CC604
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8IYM9TRI22_HUMAN
E3 ubiquitin-protein ligase TRIM22
TRIM22 RNF94, STAF50
498Annotation score:
C9J060C9J060_HUMAN
E3 ubiquitin-protein ligase TRIM22
TRIM22
203Annotation score:
C9JIU5C9JIU5_HUMAN
E3 ubiquitin-protein ligase TRIM22
TRIM22
227Annotation score:
H7BZD3H7BZD3_HUMAN
E3 ubiquitin-protein ligase TRIM22
TRIM22
143Annotation score:
H7C2K0H7C2K0_HUMAN
E3 ubiquitin-protein ligase TRIM22
TRIM22
63Annotation score:
H7C262H7C262_HUMAN
E3 ubiquitin-protein ligase TRIM22
TRIM22
38Annotation score:
H7C376H7C376_HUMAN
E3 ubiquitin-protein ligase TRIM22
TRIM22
37Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei305Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109341 Genomic DNA No translation available.
AC131574 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000454828; ENSP00000393250; ENSG00000132274
UCSCiuc057yil.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109341 Genomic DNA No translation available.
AC131574 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JWC5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9JWC5
PeptideAtlasiC9JWC5
PRIDEiC9JWC5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000454828; ENSP00000393250; ENSG00000132274
UCSCiuc057yil.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000132274.15
HGNCiHGNC:16379 TRIM22
OpenTargetsiENSG00000132274
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118893
HOGENOMiHOG000234134

Gene expression databases

BgeeiENSG00000132274 Expressed in 222 organ(s), highest expression level in blood
ExpressionAtlasiC9JWC5 baseline and differential

Family and domain databases

CDDicd00021 BBOX, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PfamiView protein in Pfam
PF00643 zf-B_box, 1 hit
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JWC5_HUMAN
AccessioniPrimary (citable) accession number: C9JWC5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: October 10, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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