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Protein
Submitted name:

Insulin-like growth factor-binding protein 2

Gene

IGFBP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor-binding protein 2Imported
Gene namesi
Name:IGFBP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000115457.9
HGNCiHGNC:5471 IGFBP2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000115457

PTM / Processingi

Proteomic databases

EPDiC9JW52
MaxQBiC9JW52
PeptideAtlasiC9JW52
PRIDEiC9JW52

Expressioni

Gene expression databases

BgeeiENSG00000115457 Expressed in 195 organ(s), highest expression level in decidua
ExpressionAtlasiC9JW52 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliC9JW52
SMRiC9JW52
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IHUR Eukaryota
ENOG4111GWQ LUCA
GeneTreeiENSGT00550000074457

Family and domain databases

InterProiView protein in InterPro
IPR009168 IGFBP1-6
PANTHERiPTHR11551 PTHR11551, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

C9JW52-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK
60 70
KLRPPPARTP CQQELDQVLE RISTMRLP
Length:78
Mass (Da):8,685
Last modified:November 3, 2009 - v1
Checksum:i86810BB95DC92451
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P18065IBP2_HUMAN
Insulin-like growth factor-binding ...
IGFBP2 BP2, IBP2
325Annotation score:
C9JMY1C9JMY1_HUMAN
Insulin-like growth factor-binding ...
IGFBP2
181Annotation score:
H7C1H0H7C1H0_HUMAN
Insulin-like growth factor-binding ...
IGFBP2
98Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei78Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007563 Genomic DNA No translation available.
AC073321 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000434997; ENSP00000401698; ENSG00000115457
UCSCiuc061sgc.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007563 Genomic DNA No translation available.
AC073321 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JW52
SMRiC9JW52
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiC9JW52
MaxQBiC9JW52
PeptideAtlasiC9JW52
PRIDEiC9JW52

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000434997; ENSP00000401698; ENSG00000115457
UCSCiuc061sgc.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000115457.9
HGNCiHGNC:5471 IGFBP2
OpenTargetsiENSG00000115457
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IHUR Eukaryota
ENOG4111GWQ LUCA
GeneTreeiENSGT00550000074457

Miscellaneous databases

ChiTaRSiIGFBP2 human

Gene expression databases

BgeeiENSG00000115457 Expressed in 195 organ(s), highest expression level in decidua
ExpressionAtlasiC9JW52 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR009168 IGFBP1-6
PANTHERiPTHR11551 PTHR11551, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JW52_HUMAN
AccessioniPrimary (citable) accession number: C9JW52
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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