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Protein
Submitted name:

Voltage-dependent calcium channel subunit alpha-2/delta-2

Gene

CACNA2D2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent calcium channel subunit alpha-2/delta-2Imported
Gene namesi
Name:CACNA2D2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000007402.11
HGNCiHGNC:1400 CACNA2D2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000007402

PTM / Processingi

Proteomic databases

MaxQBiC9JVC9
PRIDEiC9JVC9

Expressioni

Gene expression databases

BgeeiENSG00000007402
ExpressionAtlasiC9JVC9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JVC9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini291 – 469VWFAInterPro annotationAdd BLAST179

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili123 – 147Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2353 Eukaryota
ENOG410XPDX LUCA
GeneTreeiENSGT00530000062904
HOGENOMiHOG000004860
OMAiFLNLAWW
OrthoDBiEOG091G00UY
PhylomeDBiC9JVC9

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR013680 VDCC_a2/dsu
IPR013608 VWA_N
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF08473 VGCC_alpha2, 1 hit
PF00092 VWA, 1 hit
PF08399 VWA_N, 1 hit
SMARTiView protein in SMART
SM00327 VWA, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50234 VWFA, 1 hit

Sequencei

Sequence statusi: Complete.

C9JVC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVPARTCGA SRPGPARTAR PWPGCGPHPG PGTRRPTSGP PRPLWLLLPL
60 70 80 90 100
LPLLAAPGAS AYSFPQQHTM QHWARRLEQE VDGVMRIFGG VQQLREIYKD
110 120 130 140 150
NRNLFEVQEN EPQKLVEKVA GDIESLLDRK VQALKRLADA AENFQKAHRW
160 170 180 190 200
QDNIKEEDIV YYDAKADAEL DDPESEDVER GSKASTLRLD FIEDPNFKNK
210 220 230 240 250
VNYSYAAVQI PTDIYKGSTV ILNELNWTEA LENVFMENRR QDPTLLWQVF
260 270 280 290 300
GSATGVTRYY PATPWRAPKK IDLYDVRRRP WYIQGASSPK DMVIIVDVSG
310 320 330 340 350
SVSGLTLKLM KTSVCEMLDT LSDDDYVNVA SFNEKAQPVS CFTHLVQANV
360 370 380 390 400
RNKKVFKEAV QGMVAKGTTG YKAGFEYAFD QLQNSNITRA NCNKMIMMFT
410 420 430 440 450
DGGEDRVQDV FEKYNWPNRT VRVFTFSVGQ HNYDVTPLQW MACANKGYYF
460 470 480 490 500
EIPSIGAIRI NTQEYLDVLG RPMVLAGKEA KQVQWTNVYE DALGLGLVVT
510 520 530 540 550
GTLPVFNLTQ DGPGEKKNQL ILGVMGIDVA LNDIKRLTPN YTLGANGYVF
560 570 580 590 600
AIDLNGYVLL HPNLKPQTTN FREPVTLDFL DAELEDENKE EIRRSMIDGN
610 620 630 640 650
KGHKQIRTLV KSLDERYIDE VTRNYTWVPI RSTNYSLGLV LPPYSTFYLQ
660 670 680 690 700
ANLSDQILQV KLPISKLKDF EFLLPSSFES EGHVFIAPRE YCKDLNASDN
710 720 730 740 750
NTEFLKNFIE LMEKVTPDSK QCNNFLLHNL ILDTGITQQL VERVWRDQDL
760 770 780 790 800
NTYSLLAVFA ATDGGITRVF PNKAAEDWTE NPEPFNASFY RRSLDNHGYV
810 820 830 840 850
FKPPHQDALL RPLELENDTV GILVSTAVEL SLGRRTLRPA VVGVKLDLEA
860 870 880 890 900
WAEKFKVLAS NRTHQDQPQK QCGPNSHCEM DCEVNNEDLL CVLIDDGGFL
910 920 930 940 950
VLSNQNHQWD QVGRFFSEVD ANLMLALYNN SFYTRKESYD YQAACAPQPP
960 970 980 990 1000
GNLGAAPRGV FVPTVADFLN LAWWTSAAAW SLFQQLLYGL IYHSWFQADP
1010 1020 1030 1040 1050
AEAEGSPETR ESSCVMKQTQ YYFGSVNASY NAIIDCGNCS RLFHAQRLTN
1060 1070 1080 1090 1100
TNLLFVVAEK PLCSQCEAGR LLQKETHCPA DGPEQCELVQ RPRYRRGPHI
1110 1120 1130 1140 1150
CFDYNATEDT SDCGRGASFP PSLGVLVSLQ LLLLLGLPPR PQPQVLVHAS

RRL
Length:1,153
Mass (Da):130,130
Last modified:November 3, 2009 - v1
Checksum:i584DCE45863EC645
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL450422 Genomic DNA No translation available.
KF457634 Genomic DNA No translation available.
Z75742 Genomic DNA No translation available.
Z75743 Genomic DNA No translation available.
Z84492 Genomic DNA No translation available.
Z84494 Genomic DNA No translation available.
Z84495 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000423994; ENSP00000407393; ENSG00000007402
UCSCiuc062kfh.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JVC9_HUMAN
AccessioniPrimary (citable) accession number: C9JVC9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 23, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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