Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Serpin B8

Gene

SERPINB8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Serpin B8Imported
Gene namesi
Name:SERPINB8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000166401.13
HGNCiHGNC:8952 SERPINB8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166401

PTM / Processingi

Proteomic databases

MaxQBiC9JVA8
PeptideAtlasiC9JVA8
PRIDEiC9JVA8

Expressioni

Gene expression databases

BgeeiENSG00000166401 Expressed in 114 organ(s), highest expression level in skin of leg
ExpressionAtlasiC9JVA8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JVA8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 164SERPINInterPro annotationAdd BLAST152

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118789
HOGENOMiHOG000238519

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

C9JVA8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDLCEANGT FAISLFKILG EEDNSRNVFF SPMSISSALA MVFMGAKGST
60 70 80 90 100
AAQMSQALCL YKDGDIHRGF QSLLSEVNRT GTQYLLRTAN RLFGEKTCDF
110 120 130 140 150
LPDFKEYCQK FYQAELEELS FAEDTEECRK HINDWVAEKT EGKISEVLDA
160
GTVDPLTKLV LVNA
Length:164
Mass (Da):18,333
Last modified:November 3, 2009 - v1
Checksum:iBAA6617B937F48A2
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P50452SPB8_HUMAN
Serpin B8
SERPINB8 PI8
374Annotation score:
C9JTJ8C9JTJ8_HUMAN
Serpin B8
SERPINB8
124Annotation score:
H7BXK7H7BXK7_HUMAN
Serpin B8
SERPINB8
189Annotation score:
A0A1B0GU38A0A1B0GU38_HUMAN
Serpin B8
SERPINB8
259Annotation score:
A0A087WTX6A0A087WTX6_HUMAN
Serpin B8
SERPINB8
43Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei164Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009802 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000441827; ENSP00000393456; ENSG00000166401
UCSCiuc060pwr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009802 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JVA8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9JVA8
PeptideAtlasiC9JVA8
PRIDEiC9JVA8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000441827; ENSP00000393456; ENSG00000166401
UCSCiuc060pwr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000166401.13
HGNCiHGNC:8952 SERPINB8
OpenTargetsiENSG00000166401
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118789
HOGENOMiHOG000238519

Gene expression databases

BgeeiENSG00000166401 Expressed in 114 organ(s), highest expression level in skin of leg
ExpressionAtlasiC9JVA8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JVA8_HUMAN
AccessioniPrimary (citable) accession number: C9JVA8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again