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Protein

Putative adrenomedullin-5-like protein

Gene

ADM5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable non-functional remnant of adrenomedullin-5.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
Putative adrenomedullin-5-like protein
Gene namesi
Name:ADM5
Synonyms:C19orf76
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000224420.3
HGNCiHGNC:27293 ADM5
neXtProtiNX_C9JUS6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000224420
PharmGKBiPA165393101

Polymorphism and mutation databases

BioMutaiADM5

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000039255119 – 153Putative adrenomedullin-5-like proteinAdd BLAST135

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi39 ↔ 44By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiC9JUS6
PRIDEiC9JUS6
ProteomicsDBi11773

Expressioni

Gene expression databases

BgeeiENSG00000224420
GenevisibleiC9JUS6 HS

Structurei

3D structure databases

ProteinModelPortaliC9JUS6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adrenomedullin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JMZP Eukaryota
ENOG41116Z5 LUCA
GeneTreeiENSGT00730000112484
HOGENOMiHOG000170821
InParanoidiC9JUS6
OMAiAQCPARW
OrthoDBiEOG091G1284
PhylomeDBiC9JUS6

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C9JUS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIHILILLL LLAFSAQGDL DTAARRGQHQ VPQHRGHVCY LGVCRTHRLA
60 70 80 90 100
EIIYWIRCLH QGALGEGQPR APGPLQLWAP PVARGGSPAR FPGFRPAARG
110 120 130 140 150
LAQCPARWVT SGTARPLLGF SLPICMLELL LHISSPLTPA PETVFPSPSP

GCD
Length:153
Mass (Da):16,532
Last modified:November 3, 2009 - v1
Checksum:i2AC1CFBEB867B30D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011495 Genomic DNA No translation available.
CH471177 Genomic DNA Translation: EAW52522.1
BC032764 mRNA No translation available.
CCDSiCCDS46146.1
RefSeqiNP_001094810.1, NM_001101340.1
UniGeneiHs.311193
Hs.607562

Genome annotation databases

EnsembliENST00000420022; ENSP00000393631; ENSG00000224420
GeneIDi199800
KEGGihsa:199800
UCSCiuc002pph.3 human

Similar proteinsi

Entry informationi

Entry nameiADM5_HUMAN
AccessioniPrimary (citable) accession number: C9JUS6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: November 3, 2009
Last modified: June 20, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

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