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Protein
Submitted name:

Ras-responsive element-binding protein 1

Gene

RREB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Ras-responsive element-binding protein 1Imported
Gene namesi
Name:RREB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000124782.19
HGNCiHGNC:10449 RREB1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000124782

PTM / Processingi

Proteomic databases

MaxQBiC9JU34
PaxDbiC9JU34
PeptideAtlasiC9JU34
PRIDEiC9JU34

Expressioni

Gene expression databases

BgeeiENSG00000124782 Expressed in 230 organ(s), highest expression level in epithelium of mammary gland
ExpressionAtlasiC9JU34 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000369270

Structurei

3D structure databases

ProteinModelPortaliC9JU34
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 93C2H2-typeInterPro annotationAdd BLAST28
Domaini97 – 124C2H2-typeInterPro annotationAdd BLAST28
Domaini125 – 152C2H2-typeInterPro annotationAdd BLAST28
Domaini208 – 235C2H2-typeInterPro annotationAdd BLAST28
Domaini316 – 343C2H2-typeInterPro annotationAdd BLAST28
Domaini643 – 670C2H2-typeInterPro annotationAdd BLAST28
Domaini671 – 698C2H2-typeInterPro annotationAdd BLAST28
Domaini699 – 722C2H2-typeInterPro annotationAdd BLAST24
Domaini753 – 778C2H2-typeInterPro annotationAdd BLAST26

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00930000150976
HOGENOMiHOG000154195

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 10 hits
SUPFAMiSSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 9 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

C9JU34-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSSSPAGLE GSDLSSINTM MSAVMSVGKV TENGGSPQGI KSPSKPPGPN
60 70 80 90 100
RIGRRNQETK EEKSSYNCPL CEKICTTQHQ LTMHIRQHNT DTGGADHSCS
110 120 130 140 150
ICGKSLSSAS SLDRHMLVHS GERPYKCTVC GQSFTTNGNM HRHMKIHEKD
160 170 180 190 200
PNSATATAPP SPLKRRRLSS KRKLSHDAES EREDPAPAKK MVEDGQSGDL
210 220 230 240 250
EKKADEVFHC PVCFKEFVCK YGLETHMETH SDNPLRCDIC CVTFRTHRGL
260 270 280 290 300
LRHNALVHKQ LPRDAMGRPF IQNNPSIPAG FHDLGFTDFS CRKFPRISQA
310 320 330 340 350
WCETNLRRCI SEQHRFVCDT CDKAFPMLCS LALHKQTHVA ADQGQEKPQA
360 370 380 390 400
TPLPGDALDQ KGFLALLGLQ HTKDVRPAPA EEPLPDDNQA IQLQTLKCQL
410 420 430 440 450
PQDPGCTNLL SLSPFEAASL GGSLTVLPAT KDSIKHLSLQ PFQKGFIIQP
460 470 480 490 500
DSSIVVKPIS GESAIELADI QQILKMAASA PPQISLPPFS KAPAAPLQAI
510 520 530 540 550
FKHMPPLKPK PLVTPRTVVA TSTPPPLINA QQASPGCISP SLPPPPLKLL
560 570 580 590 600
KGSVEAASNA HLLQSKSGTQ PHAATRLSLQ QPRAELPGQP EMKTQLEQDS
610 620 630 640 650
IIEALLPLSM EAKIKQEITE GELKAFMTAP GGKKTPAMRK VLYPCRFCNQ
660 670 680 690 700
VFAFSGVLRA HVRSHLGISP YQCNICDYIA ADKAALIRHL RTHSGERPYI
710 720 730 740 750
CKICHYPFTV KANCERHLRK KHLKATRKDI EKNIEYVSSS AAELVDAFCA
760 770
PDTVCRLCGE DLKHYRALRI HMRTHCGR
Length:778
Mass (Da):85,481
Last modified:November 3, 2009 - v1
Checksum:i6D6EFD32B69CE384
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q92766RREB1_HUMAN
Ras-responsive element-binding prot...
RREB1 FINB
1,687Annotation score:
A0A087X055A0A087X055_HUMAN
Ras-responsive element-binding prot...
RREB1
755Annotation score:
C9JPJ6C9JPJ6_HUMAN
Ras-responsive element-binding prot...
RREB1
164Annotation score:
C9JE09C9JE09_HUMAN
Ras-responsive element-binding prot...
RREB1
136Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei778Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139095 Genomic DNA No translation available.
AL355336 Genomic DNA No translation available.
AL589644 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000483150; ENSP00000419511; ENSG00000124782
UCSCiuc063lqp.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139095 Genomic DNA No translation available.
AL355336 Genomic DNA No translation available.
AL589644 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JU34
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000369270

Proteomic databases

MaxQBiC9JU34
PaxDbiC9JU34
PeptideAtlasiC9JU34
PRIDEiC9JU34

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000483150; ENSP00000419511; ENSG00000124782
UCSCiuc063lqp.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000124782.19
HGNCiHGNC:10449 RREB1
OpenTargetsiENSG00000124782
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00930000150976
HOGENOMiHOG000154195

Miscellaneous databases

ChiTaRSiRREB1 human

Gene expression databases

BgeeiENSG00000124782 Expressed in 230 organ(s), highest expression level in epithelium of mammary gland
ExpressionAtlasiC9JU34 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 10 hits
SUPFAMiSSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 9 hits
ProtoNetiSearch...

Entry informationi

Entry nameiC9JU34_HUMAN
AccessioniPrimary (citable) accession number: C9JU34
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: November 7, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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