UniProtKB - C9JU00 (C9JU00_HUMAN)
Protein
Submitted name:
Fibrinogen gamma chain
Gene
FGG
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- signaling receptor binding Source: InterPro
GO - Biological processi
- platelet activation Source: InterPro
- protein polymerization Source: InterPro
Keywordsi
Biological process | Blood coagulationARBA annotation, Hemostasis |
Ligand | CalciumARBA annotation, Metal-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Fibrinogen gamma chainImported |
Gene namesi | Name:FGGImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:3694, FGG |
VEuPathDBi | HostDB:ENSG00000171557.16 |
Subcellular locationi
Extracellular region or secreted
- Secreted ARBA annotation
Extracellular region or secreted
- fibrinogen complex Source: InterPro
Keywords - Cellular componenti
SecretedARBA annotationPTM / Processingi
Keywords - PTMi
Disulfide bondARBA annotation, GlycoproteinARBA annotationProteomic databases
MaxQBi | C9JU00 |
PeptideAtlasi | C9JU00 |
PRIDEi | C9JU00 |
ProteomicsDBi | 11663 |
Expressioni
Gene expression databases
Bgeei | ENSG00000171557, Expressed in liver and 118 other tissues |
ExpressionAtlasi | C9JU00, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 67 – 123 | Fibrinogen C-terminalInterPro annotationAdd BLAST | 57 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 37 – 57 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000158467 |
HOGENOMi | CLU_2066734_0_0_1 |
Family and domain databases
Gene3Di | 3.90.215.10, 1 hit |
InterProi | View protein in InterPro IPR036056, Fibrinogen-like_C IPR014716, Fibrinogen_a/b/g_C_1 IPR002181, Fibrinogen_a/b/g_C_dom IPR012290, Fibrinogen_a/b/g_coil_dom IPR037581, Fibrinogen_gamma |
PANTHERi | PTHR19143:SF338, PTHR19143:SF338, 1 hit |
Pfami | View protein in Pfam PF08702, Fib_alpha, 1 hit PF00147, Fibrinogen_C, 1 hit |
SMARTi | View protein in SMART SM01212, Fib_alpha, 1 hit |
SUPFAMi | SSF56496, SSF56496, 1 hit |
PROSITEi | View protein in PROSITE PS51406, FIBRINOGEN_C_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
C9JU00-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIDAATLKSR KMLEEIMKYE ASILTHDSSI RYLQEIYNSN NQKIVNLKEK
60 70 80 90 100
VAQLEAQCQE PCKDTVQIHD ITGKDCQDIA NKGAKQSGLY FIKPLKANQQ
110 120
FLVYCEIDGS GNGWTVFQKR LDG
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP02679 | FIBG_HUMAN | Fibrinogen gamma chain | FGG PRO2061 | 453 | Annotation score: | ||
C9JC84 | C9JC84_HUMAN | Fibrinogen gamma chain | FGG | 461 | Annotation score: | ||
C9JEU5 | C9JEU5_HUMAN | Fibrinogen gamma chain | FGG | 445 | Annotation score: | ||
C9JPQ9 | C9JPQ9_HUMAN | Fibrinogen gamma chain | FGG | 119 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 123 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC107385 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000443553; ENSP00000407562; ENSG00000171557 |
UCSCi | uc063ajz.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC107385 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | C9JU00 |
PeptideAtlasi | C9JU00 |
PRIDEi | C9JU00 |
ProteomicsDBi | 11663 |
Protocols and materials databases
Antibodypediai | 16774, 636 antibodies |
Genome annotation databases
Ensembli | ENST00000443553; ENSP00000407562; ENSG00000171557 |
UCSCi | uc063ajz.1, human |
Organism-specific databases
HGNCi | HGNC:3694, FGG |
OpenTargetsi | ENSG00000171557 |
VEuPathDBi | HostDB:ENSG00000171557.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158467 |
HOGENOMi | CLU_2066734_0_0_1 |
Miscellaneous databases
ChiTaRSi | FGG, human |
Gene expression databases
Bgeei | ENSG00000171557, Expressed in liver and 118 other tissues |
ExpressionAtlasi | C9JU00, baseline and differential |
Family and domain databases
Gene3Di | 3.90.215.10, 1 hit |
InterProi | View protein in InterPro IPR036056, Fibrinogen-like_C IPR014716, Fibrinogen_a/b/g_C_1 IPR002181, Fibrinogen_a/b/g_C_dom IPR012290, Fibrinogen_a/b/g_coil_dom IPR037581, Fibrinogen_gamma |
PANTHERi | PTHR19143:SF338, PTHR19143:SF338, 1 hit |
Pfami | View protein in Pfam PF08702, Fib_alpha, 1 hit PF00147, Fibrinogen_C, 1 hit |
SMARTi | View protein in SMART SM01212, Fib_alpha, 1 hit |
SUPFAMi | SSF56496, SSF56496, 1 hit |
PROSITEi | View protein in PROSITE PS51406, FIBRINOGEN_C_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9JU00_HUMAN | |
Accessioni | C9JU00Primary (citable) accession number: C9JU00 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | February 10, 2021 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |