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Protein
Submitted name:

Dynactin subunit 1

Gene

DCTN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dynactin subunit 1Imported
Gene namesi
Name:DCTN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000204843.12
HGNCiHGNC:2711 DCTN1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204843

PTM / Processingi

Proteomic databases

PeptideAtlasiC9JTE5
PRIDEiC9JTE5

Expressioni

Gene expression databases

BgeeiENSG00000204843 Expressed in 223 organ(s), highest expression level in frontal cortex
ExpressionAtlasiC9JTE5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JTE5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 73CAP-GlyInterPro annotationAdd BLAST43

Phylogenomic databases

eggNOGiKOG0971 Eukaryota
COG5244 LUCA
GeneTreeiENSGT00760000119173

Family and domain databases

Gene3Di2.30.30.190, 1 hit
InterProiView protein in InterPro
IPR036859 CAP-Gly_dom_sf
IPR000938 CAP-Gly_domain
IPR027663 DCTN1
PANTHERiPTHR18916:SF40 PTHR18916:SF40, 1 hit
PfamiView protein in Pfam
PF01302 CAP_GLY, 1 hit
SMARTiView protein in SMART
SM01052 CAP_GLY, 1 hit
SUPFAMiSSF74924 SSF74924, 1 hit
PROSITEiView protein in PROSITE
PS00845 CAP_GLY_1, 1 hit
PS50245 CAP_GLY_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

C9JTE5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAEASARPL RVGSRVEVIG KGHRGTVAYV GATLFATGKW VGVILDEAKG
60 70
KNDGTVQGRK YFTCDEGHGI FVRQSQ
Length:76
Mass (Da):8,123
Last modified:November 3, 2009 - v1
Checksum:iFD0496A2F5D35775
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q14203DCTN1_HUMAN
Dynactin subunit 1
DCTN1
1,278Annotation score:
E7EX90E7EX90_HUMAN
Dynactin subunit 1
DCTN1
1,256Annotation score:
Q6AWB1Q6AWB1_HUMAN
Dynactin subunit 1
DCTN1 DKFZp686E0752
890Annotation score:
C9JKG6C9JKG6_HUMAN
Dynactin subunit 1
DCTN1
135Annotation score:
C9JJD0C9JJD0_HUMAN
Dynactin subunit 1
DCTN1
121Annotation score:
E9PCY0E9PCY0_HUMAN
Dynactin subunit 1
DCTN1
186Annotation score:
C9JJN7C9JJN7_HUMAN
Dynactin subunit 1
DCTN1
87Annotation score:
C9J1B7C9J1B7_HUMAN
Dynactin subunit 1
DCTN1
64Annotation score:
C9JZA4C9JZA4_HUMAN
Dynactin subunit 1
DCTN1
76Annotation score:
C9JUI8C9JUI8_HUMAN
Dynactin subunit 1
DCTN1
13Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei76Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005041 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000421392; ENSP00000409363; ENSG00000204843

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005041 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JTE5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9JTE5
PRIDEiC9JTE5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000421392; ENSP00000409363; ENSG00000204843

Organism-specific databases

EuPathDBiHostDB:ENSG00000204843.12
HGNCiHGNC:2711 DCTN1
OpenTargetsiENSG00000204843
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0971 Eukaryota
COG5244 LUCA
GeneTreeiENSGT00760000119173

Miscellaneous databases

ChiTaRSiDCTN1 human

Gene expression databases

BgeeiENSG00000204843 Expressed in 223 organ(s), highest expression level in frontal cortex
ExpressionAtlasiC9JTE5 baseline and differential

Family and domain databases

Gene3Di2.30.30.190, 1 hit
InterProiView protein in InterPro
IPR036859 CAP-Gly_dom_sf
IPR000938 CAP-Gly_domain
IPR027663 DCTN1
PANTHERiPTHR18916:SF40 PTHR18916:SF40, 1 hit
PfamiView protein in Pfam
PF01302 CAP_GLY, 1 hit
SMARTiView protein in SMART
SM01052 CAP_GLY, 1 hit
SUPFAMiSSF74924 SSF74924, 1 hit
PROSITEiView protein in PROSITE
PS00845 CAP_GLY_1, 1 hit
PS50245 CAP_GLY_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JTE5_HUMAN
AccessioniPrimary (citable) accession number: C9JTE5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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