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Protein
Submitted name:

C-reactive protein

Gene

CRP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
C-reactive proteinImported
Gene namesi
Name:CRPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000132693.12
HGNCiHGNC:2367 CRP

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132693

PTM / Processingi

Proteomic databases

PeptideAtlasiC9JRE9
PRIDEiC9JRE9

Expressioni

Gene expression databases

BgeeiENSG00000132693 Expressed in 86 organ(s), highest expression level in right lobe of liver
ExpressionAtlasiC9JRE9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JRE9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410J9V0 Eukaryota
ENOG410YIJN LUCA
GeneTreeiENSGT00760000119128
HOGENOMiHOG000168947

Family and domain databases

InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR001759 Pentraxin-related
PfamiView protein in Pfam
PF00354 Pentaxin, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS51828 PTX_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

C9JRE9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40 
MWDFVLSPDE INTIYLGGPF SPNVLNWRAL KYEVQGEVFT KPQLWP
Length:46
Mass (Da):5,397
Last modified:November 3, 2009 - v1
Checksum:i27B074F61F04325B
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P02741CRP_HUMAN
C-reactive protein
CRP PTX1
224Annotation score:
Q5VVP7Q5VVP7_HUMAN
C-reactive protein
CRP
102Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445528 Genomic DNA No translation available.
UniGeneiHs.709456
Hs.76452

Genome annotation databases

EnsembliENST00000437342; ENSP00000402788; ENSG00000132693
UCSCiuc057mhb.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445528 Genomic DNA No translation available.
UniGeneiHs.709456
Hs.76452

3D structure databases

ProteinModelPortaliC9JRE9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9JRE9
PRIDEiC9JRE9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000437342; ENSP00000402788; ENSG00000132693
UCSCiuc057mhb.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000132693.12
HGNCiHGNC:2367 CRP
OpenTargetsiENSG00000132693
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J9V0 Eukaryota
ENOG410YIJN LUCA
GeneTreeiENSGT00760000119128
HOGENOMiHOG000168947

Miscellaneous databases

ChiTaRSiCRP human

Gene expression databases

BgeeiENSG00000132693 Expressed in 86 organ(s), highest expression level in right lobe of liver
ExpressionAtlasiC9JRE9 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR001759 Pentraxin-related
PfamiView protein in Pfam
PF00354 Pentaxin, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS51828 PTX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JRE9_HUMAN
AccessioniPrimary (citable) accession number: C9JRE9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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