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Protein
Submitted name:

COP9 signalosome complex subunit 6

Gene

COPS6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
COP9 signalosome complex subunit 6Imported
Gene namesi
Name:COPS6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000168090.9
HGNCiHGNC:21749 COPS6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168090

PTM / Processingi

Proteomic databases

PeptideAtlasiC9JQK5

Expressioni

Gene expression databases

BgeeiENSG00000168090 Expressed in 231 organ(s), highest expression level in testis
ExpressionAtlasiC9JQK5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JQK5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3050 Eukaryota
COG1310 LUCA
GeneTreeiENSGT00530000063075

Family and domain databases

InterProiView protein in InterPro
IPR033859 MPN_CSN6
PANTHERiPTHR10540:SF8 PTHR10540:SF8, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

C9JQK5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40 
MACGVTGSVS VALHPLVILN ISDHWIRMRS QEGRPVQVIG A
Length:41
Mass (Da):4,399
Last modified:October 5, 2016 - v8
Checksum:i15C6A10CFAE0567C
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q7L5N1CSN6_HUMAN
COP9 signalosome complex subunit 6
COPS6 CSN6, HVIP
327Annotation score:
E7EM64E7EM64_HUMAN
COP9 signalosome complex subunit 6
COPS6
326Annotation score:
H7C3T0H7C3T0_HUMAN
COP9 signalosome complex subunit 6
COPS6
123Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei41Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073842 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000419210; ENSP00000388865; ENSG00000168090
UCSCiuc064fyr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073842 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JQK5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9JQK5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000419210; ENSP00000388865; ENSG00000168090
UCSCiuc064fyr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000168090.9
HGNCiHGNC:21749 COPS6
OpenTargetsiENSG00000168090
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3050 Eukaryota
COG1310 LUCA
GeneTreeiENSGT00530000063075

Miscellaneous databases

ChiTaRSiCOPS6 human

Gene expression databases

BgeeiENSG00000168090 Expressed in 231 organ(s), highest expression level in testis
ExpressionAtlasiC9JQK5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR033859 MPN_CSN6
PANTHERiPTHR10540:SF8 PTHR10540:SF8, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JQK5_HUMAN
AccessioniPrimary (citable) accession number: C9JQK5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 60 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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