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UniProtKB - C9JQI7 (TM232_HUMAN)

Entry version 78 (10 Feb 2021)
Sequence version 2 (15 Jun 2010)
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Protein

Transmembrane protein 232

Gene

TMEM232

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		C9JQI7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 232
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM232
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:37270, TMEM232

neXtProt; the human protein knowledge platform

More...neXtProti		NX_C9JQI7

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000186952.14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Transmembranei353 – 373HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		642987

Open Targets

More...OpenTargetsi		ENSG00000186952

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA165660571

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		C9JQI7, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TMEM232

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003950351 – 657Transmembrane protein 232Add BLAST657

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		C9JQI7

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		C9JQI7

PeptideAtlas

More...PeptideAtlasi		C9JQI7

PRoteomics IDEntifications database

More...PRIDEi		C9JQI7

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		11246 [C9JQI7-1]
11247 [C9JQI7-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		C9JQI7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		C9JQI7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000186952, Expressed in testis and 136 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		C9JQI7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		C9JQI7, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000186952, Tissue enhanced (fallopian tube, pituitary gland, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		568408, 2 interactors

Protein interaction database and analysis system

More...IntActi		C9JQI7, 2 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000401477

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		C9JQI7, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QVVE, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000014003

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_015366_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		C9JQI7

Identification of Orthologs from Complete Genome Data

More...OMAi		QEVMKKR

Database of Orthologous Groups

More...OrthoDBi		679293at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		C9JQI7

TreeFam database of animal gene trees

More...TreeFami		TF336968

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR031747, TMEM232

The PANTHER Classification System

More...PANTHERi		PTHR28651, PTHR28651, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15877, TMEM232, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 2 (identifier: C9JQI7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNMPVNKSPM INTCGGISSP YHEELWKLNF QHLSGERGHK SRPTFSITKE 
        60         70         80         90        100
FILRFNQTQN SKEKEELLEL ARKIILRCKR KLGLKTLGSG RHVHLPAAWT 
       110        120        130        140        150
EVIYLAQCKG EIQDESLNML YASLDHASFD YDHLPALFFV AESVLYRLCC 
       160        170        180        190        200
DASLKTYLYS VEIKLAKIGY LVFLRLFIFF LHGHLESFKQ HLLRLQPYLY 
       210        220        230        240        250
ALSFSGASYH KYPNIFSNVQ FILKASEIIG KRELRSESIF RPVEDKKRYE 
       260        270        280        290        300
NTDSDMGGYE INHLLWHCVA AWSCVQNNSP QLNNVLEHLV FHKTQLQKKC 
       310        320        330        340        350
WLDSVLALLV LGEAAKLNMA CLKALMDVVR DFVSSIMSVQ NQEESCKVDD 
       360        370        380        390        400
FSWAWNVVYI YTVILAEICL YAATSDLRKT ALIGFCHCKS SQKNILYLDK 
       410        420        430        440        450
SVPPELKETS ILSLLEYFSS KMSENCDQVV WTGYYGLVYN LVKISWELQG 
       460        470        480        490        500
DEEQDGLRNM IWQTLQKTKD YEEDVRIQNA INIAQAELND PTDPFTRYST 
       510        520        530        540        550
NISSNVGEEV FSKYIGWRIA NTLSKLFFPP IEAHFLPLKK PSIKKDQTKY 
       560        570        580        590        600
PNKKLESVKK QVLHFTVREH PSVSEIPMFP YPDFFTKADK ELAKIIDHHW 
       610        620        630        640        650
QEELKIREKE DAICKAQELK DKKLAEKNHF QEVMKKREEK LHKQTKPYEL 

PYRKEVI
Length:657
Mass (Da):76,453
Last modified:June 15, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1E6D0910A3422E1E
GO
Isoform 1 (identifier: C9JQI7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     486-657: AELNDPTDPF...YELPYRKEVI → GTSFCIRNSHVSISRFLHQGR

Show »
Length:506
Mass (Da):58,417
Checksum:i164810E637D8D474
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6REY3D6REY3_HUMAN
Transmembrane protein 232
TMEM232
164Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RF96D6RF96_HUMAN
Transmembrane protein 232
TMEM232
119Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RC30D6RC30_HUMAN
Transmembrane protein 232
TMEM232
247Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RG73E5RG73_HUMAN
Transmembrane protein 232
TMEM232
59Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_039352486 – 657AELND…RKEVI → GTSFCIRNSHVSISRFLHQG R in isoform 1. CuratedAdd BLAST172

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK296542 mRNA Translation: BAG59166.1
AC008650 Genomic DNA No translation available.
AC010349 Genomic DNA No translation available.
AC012622 Genomic DNA No translation available.
AC114290 Genomic DNA No translation available.
CH471086 Genomic DNA Translation: EAW49042.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS47253.2 [C9JQI7-1]

NCBI Reference Sequences

More...RefSeqi		NP_001034852.3, NM_001039763.3 [C9JQI7-1]
XP_006714733.1, XM_006714670.3 [C9JQI7-1]
XP_011541854.1, XM_011543552.2 [C9JQI7-1]
XP_011541855.1, XM_011543553.2 [C9JQI7-1]
XP_011541866.1, XM_011543564.2 [C9JQI7-2]
XP_016865193.1, XM_017009704.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000455884; ENSP00000401477; ENSG00000186952 [C9JQI7-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		642987

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:642987

UCSC genome browser

More...UCSCi		uc011cvh.4, human [C9JQI7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296542 mRNA Translation: BAG59166.1
AC008650 Genomic DNA No translation available.
AC010349 Genomic DNA No translation available.
AC012622 Genomic DNA No translation available.
AC114290 Genomic DNA No translation available.
CH471086 Genomic DNA Translation: EAW49042.1
CCDSiCCDS47253.2 [C9JQI7-1]
RefSeqiNP_001034852.3, NM_001039763.3 [C9JQI7-1]
XP_006714733.1, XM_006714670.3 [C9JQI7-1]
XP_011541854.1, XM_011543552.2 [C9JQI7-1]
XP_011541855.1, XM_011543553.2 [C9JQI7-1]
XP_011541866.1, XM_011543564.2 [C9JQI7-2]
XP_016865193.1, XM_017009704.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi568408, 2 interactors
IntActiC9JQI7, 2 interactors
STRINGi9606.ENSP00000401477

PTM databases

iPTMnetiC9JQI7
PhosphoSitePlusiC9JQI7

Genetic variation databases

BioMutaiTMEM232

Proteomic databases

MassIVEiC9JQI7
PaxDbiC9JQI7
PeptideAtlasiC9JQI7
PRIDEiC9JQI7
ProteomicsDBi11246 [C9JQI7-1]
11247 [C9JQI7-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		57493, 16 antibodies

Genome annotation databases

EnsembliENST00000455884; ENSP00000401477; ENSG00000186952 [C9JQI7-1]
GeneIDi642987
KEGGihsa:642987
UCSCiuc011cvh.4, human [C9JQI7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		642987
DisGeNETi642987

GeneCards: human genes, protein and diseases

More...GeneCardsi		TMEM232
HGNCiHGNC:37270, TMEM232
HPAiENSG00000186952, Tissue enhanced (fallopian tube, pituitary gland, testis)
neXtProtiNX_C9JQI7
OpenTargetsiENSG00000186952
PharmGKBiPA165660571
VEuPathDBiHostDB:ENSG00000186952.14

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QVVE, Eukaryota
GeneTreeiENSGT00390000014003
HOGENOMiCLU_015366_1_0_1
InParanoidiC9JQI7
OMAiQEVMKKR
OrthoDBi679293at2759
PhylomeDBiC9JQI7
TreeFamiTF336968

Enzyme and pathway databases

PathwayCommonsiC9JQI7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		642987, 3 hits in 871 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TMEM232, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		642987
PharosiC9JQI7, Tdark

Protein Ontology

More...PROi		PR:C9JQI7
RNActiC9JQI7, protein

Gene expression databases

BgeeiENSG00000186952, Expressed in testis and 136 other tissues
ExpressionAtlasiC9JQI7, baseline and differential
GenevisibleiC9JQI7, HS

Family and domain databases

InterProiView protein in InterPro
IPR031747, TMEM232
PANTHERiPTHR28651, PTHR28651, 1 hit
PfamiView protein in Pfam
PF15877, TMEM232, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM232_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C9JQI7
Secondary accession number(s): B4DKF4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: February 10, 2021
This is version 78 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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