UniProtKB - C9JQ02 (C9JQ02_HUMAN)
Protein
Submitted name:
Exportin-1
Gene
XPO1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- Ran GTPase binding Source: InterPro
GO - Biological processi
- intracellular protein transport Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Exportin-1Imported |
Gene namesi | Name:XPO1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000082898.16 |
HGNCi | HGNC:12825, XPO1 |
Subcellular locationi
Expressioni
Gene expression databases
Bgeei | ENSG00000082898, Expressed in female gonad and 252 other tissues |
ExpressionAtlasi | C9JQ02, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 46 – 95 | Importin N-terminalInterPro annotationAdd BLAST | 50 |
Phylogenomic databases
GeneTreei | ENSGT00940000153408 |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR001494, Importin-beta_N |
Pfami | View protein in Pfam PF03810, IBN_N, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
PROSITEi | View protein in PROSITE PS50166, IMPORTIN_B_NT, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
C9JQ02-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPAIMTMLAD HAARQLLDFS QKLDINLLDN VVNCLYHGEG AQQRMAQEVL
60 70 80 90
THLKEHPDAW TRVDTILEFS QNMNTKYYGL QILENVIKTR WKILP
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO14980 | XPO1_HUMAN | Exportin-1 | XPO1 CRM1 | 1,071 | Annotation score: | ||
C9J673 | C9J673_HUMAN | Exportin-1 | XPO1 | 132 | Annotation score: | ||
C9JKM9 | C9JKM9_HUMAN | Exportin-1 | XPO1 | 179 | Annotation score: | ||
H7BZC5 | H7BZC5_HUMAN | Exportin-1 | XPO1 | 72 | Annotation score: | ||
C9IZS4 | C9IZS4_HUMAN | Exportin-1 | XPO1 | 94 | Annotation score: | ||
C9JV99 | C9JV99_HUMAN | Exportin-1 | XPO1 | 100 | Annotation score: | ||
C9IYM2 | C9IYM2_HUMAN | Exportin-1 | XPO1 | 62 | Annotation score: | ||
C9JF49 | C9JF49_HUMAN | Exportin-1 | XPO1 | 59 | Annotation score: | ||
F8WF71 | F8WF71_HUMAN | Exportin-1 | XPO1 | 82 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 95 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016727 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000422552; ENSP00000408190; ENSG00000082898 |
UCSCi | uc061joq.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016727 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | C9JQ02 |
PeptideAtlasi | C9JQ02 |
ProteomicsDBi | 11180 |
Protocols and materials databases
Antibodypediai | 4124, 345 antibodies |
Genome annotation databases
Ensembli | ENST00000422552; ENSP00000408190; ENSG00000082898 |
UCSCi | uc061joq.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000082898.16 |
HGNCi | HGNC:12825, XPO1 |
OpenTargetsi | ENSG00000082898 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000153408 |
Miscellaneous databases
ChiTaRSi | XPO1, human |
Gene expression databases
Bgeei | ENSG00000082898, Expressed in female gonad and 252 other tissues |
ExpressionAtlasi | C9JQ02, baseline and differential |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR001494, Importin-beta_N |
Pfami | View protein in Pfam PF03810, IBN_N, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
PROSITEi | View protein in PROSITE PS50166, IMPORTIN_B_NT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9JQ02_HUMAN | |
Accessioni | C9JQ02Primary (citable) accession number: C9JQ02 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | October 7, 2020 | |
This is version 68 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |