UniProtKB - C9JPI5 (C9JPI5_HUMAN)
Protein
Submitted name:
Protein polybromo-1
Gene
PBRM1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- chromatin remodeling Source: InterPro
Keywordsi
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Protein polybromo-1Imported |
Gene namesi | Name:PBRM1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:30064, PBRM1 |
VEuPathDBi | HostDB:ENSG00000163939.18 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleoplasm Source: HPA
- RSC-type complex Source: InterPro
PTM / Processingi
Proteomic databases
MaxQBi | C9JPI5 |
PeptideAtlasi | C9JPI5 |
PRIDEi | C9JPI5 |
ProteomicsDBi | 11115 |
Expressioni
Gene expression databases
Bgeei | ENSG00000163939, Expressed in forebrain and 247 other tissues |
ExpressionAtlasi | C9JPI5, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 64 – 134 | BromoInterPro annotationAdd BLAST | 71 | |
Domaini | 200 – 230 | BromoInterPro annotationAdd BLAST | 31 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 39 | DisorderedSequence analysisAdd BLAST | 39 | |
Regioni | 155 – 177 | DisorderedSequence analysisAdd BLAST | 23 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 21 | PolarSequence analysisAdd BLAST | 21 |
Keywords - Domaini
BromodomainPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00390000003017 |
HOGENOMi | CLU_032428_1_0_1 |
Family and domain databases
Gene3Di | 1.20.920.10, 2 hits |
InterProi | View protein in InterPro IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR037382, Rsc/polybromo |
PANTHERi | PTHR16062, PTHR16062, 1 hit |
Pfami | View protein in Pfam PF00439, Bromodomain, 2 hits |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00297, BROMO, 1 hit |
SUPFAMi | SSF47370, SSF47370, 2 hits |
PROSITEi | View protein in PROSITE PS00633, BROMODOMAIN_1, 1 hit PS50014, BROMODOMAIN_2, 2 hits |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
C9JPI5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSKRRRATS PSSSVSGDFD DGHHSVSTPG PSRKRRRLSN LPTVDPIAVC
60 70 80 90 100
HELYNTIRDY KDEQGRLLCE LFIRAPKRRN QPDYYEVVSQ PIDLMKIQQK
110 120 130 140 150
LKMEEYDDVN LLTADFQLLF NNAKSYYKPD SPEYKAACKL WDLYLRTRNE
160 170 180 190 200
FVQKGEADDE DDDEDGQDNQ GTVTEGSSPA YLKEILEQLL EAIVVATNPS
210 220 230
GRLISELFQK LPSKVQYPDY YAIIKEPIDL
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ86U86 | PB1_HUMAN | Protein polybromo-1 | PBRM1 BAF180, PB1 | 1,689 | Annotation score: | ||
E7EVG2 | E7EVG2_HUMAN | Protein polybromo-1 | PBRM1 | 1,460 | Annotation score: | ||
H0Y5B5 | H0Y5B5_HUMAN | Protein polybromo-1 | PBRM1 | 1,085 | Annotation score: | ||
C9J053 | C9J053_HUMAN | Protein polybromo-1 | PBRM1 | 118 | Annotation score: | ||
C9JQF1 | C9JQF1_HUMAN | Protein polybromo-1 | PBRM1 | 152 | Annotation score: | ||
C9JCJ2 | C9JCJ2_HUMAN | Protein polybromo-1 | PBRM1 | 87 | Annotation score: | ||
C9J409 | C9J409_HUMAN | Protein polybromo-1 | PBRM1 | 43 | Annotation score: | ||
C9J9L6 | C9J9L6_HUMAN | Protein polybromo-1 | PBRM1 | 26 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 230 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC104446 Genomic DNA No translation available. AC112215 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000431678; ENSP00000409939; ENSG00000163939 |
UCSCi | uc062knz.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC104446 Genomic DNA No translation available. AC112215 Genomic DNA No translation available. |
3D structure databases
SMRi | C9JPI5 |
ModBasei | Search... |
Proteomic databases
MaxQBi | C9JPI5 |
PeptideAtlasi | C9JPI5 |
PRIDEi | C9JPI5 |
ProteomicsDBi | 11115 |
Protocols and materials databases
Antibodypediai | 2905, 165 antibodies |
Genome annotation databases
Ensembli | ENST00000431678; ENSP00000409939; ENSG00000163939 |
UCSCi | uc062knz.1, human |
Organism-specific databases
HGNCi | HGNC:30064, PBRM1 |
OpenTargetsi | ENSG00000163939 |
VEuPathDBi | HostDB:ENSG00000163939.18 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000003017 |
HOGENOMi | CLU_032428_1_0_1 |
Miscellaneous databases
ChiTaRSi | PBRM1, human |
Gene expression databases
Bgeei | ENSG00000163939, Expressed in forebrain and 247 other tissues |
ExpressionAtlasi | C9JPI5, baseline and differential |
Family and domain databases
Gene3Di | 1.20.920.10, 2 hits |
InterProi | View protein in InterPro IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR037382, Rsc/polybromo |
PANTHERi | PTHR16062, PTHR16062, 1 hit |
Pfami | View protein in Pfam PF00439, Bromodomain, 2 hits |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00297, BROMO, 1 hit |
SUPFAMi | SSF47370, SSF47370, 2 hits |
PROSITEi | View protein in PROSITE PS00633, BROMODOMAIN_1, 1 hit PS50014, BROMODOMAIN_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9JPI5_HUMAN | |
Accessioni | C9JPI5Primary (citable) accession number: C9JPI5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | April 7, 2021 | |
This is version 77 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |